| Victors ID |
Gene Name |
Sequence Strain (Species/Organism) |
NCBI Gene ID |
NCBI Nucleotide GI |
NCBI Protein GI |
Locus Tag |
Genbank Accession |
Protein Accession |
Protein Name |
Molecule Role |
Molecule Role Annotation |
PMID |
|
|
pykF from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5135110
|
|
147674848
|
VC0395_A0037 |
|
YP_001216011.1 |
pyruvate kinase |
Virulence factor |
MUTATION: pykF mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
fbp from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5135123
|
|
147674062
|
VC0395_A2122 |
|
YP_001218038.1 |
fructose-1,6-bisphosphatase |
Virulence factor |
MUTATION: fbp mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
cyaA from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5135225
|
|
147673490
|
VC0395_A2397 |
|
YP_001218297.1 |
adenylate cyclase |
Virulence factor |
MUTATION: cyaA mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
fur from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5135247
|
|
147674743
|
VC0395_A1690 |
|
YP_001217629.1 |
ferric uptake regulator |
Virulence factor |
MUTATION: fur mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
mukB from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5135251
|
|
147674404
|
VC0395_A1317 |
|
YP_001217261.1 |
cell division protein MukB |
Virulence factor |
MUTATION: mukB mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
ace from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5135279
|
|
147675552
|
VC0395_A1062 |
|
YP_001217008.1 |
accessory cholera enterotoxin |
Virulence factor |
TOXIN: Ace increases short-circuit current in Ussing chambers and causes fluid secretion in ligated rabbit ileal loops [Ref6682:Trucksis et al., 1993]. |
8389476
|
|
|
frdC from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5135353
|
|
147674812
|
VC0395_A2232 |
|
YP_001218148.1 |
fumarate reductase subunit C |
Virulence factor |
MUTATION: frdC mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
rfbB from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5135444
|
|
147673913
|
VC0395_A2622 |
|
YP_001218501.1 |
phosphomannomutase |
Virulence factor |
MUTATION: rfbB mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
ubiC from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5135591
|
|
147674053
|
VC0395_A2420 |
|
YP_001218320.1 |
chorismate--pyruvate lyase |
Virulence factor |
MUTATION: ubiC mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
tolBfrom Vibrio cholerae O395 |
Vibrio cholerae O395 |
5135619
|
|
147674437
|
VC0395_A1429 |
|
YP_001217372.1 |
translocation protein TolB |
Virulence factor |
MUTATION: tolB mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
acpS from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5135659
|
|
147675265
|
VC0395_A2035 |
|
YP_001217959.1 |
4'-phosphopantetheinyl transferase |
Virulence factor |
MUTATION: acpS mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
ccmF from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5135811
|
|
147674378
|
VC0395_A1640 |
|
YP_001217579.1 |
cytochrome c-type biogenesis protein CcmF |
Virulence factor |
MUTATIOn: ccmF mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
tcpT from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5135974
|
|
147673300
|
VC0395_A0360 |
|
YP_001216316.1 |
toxin co-regulated pilus biosynthesis protein T |
Virulence factor |
MUTATION: tcpT mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
toxR |
Vibrio cholerae O395 |
5136021
|
|
147674563
|
VC0395_A0505 |
|
YP_001216456.1 |
cholera toxin transcriptional activator |
Virulence factor |
MUTATION: toxR mutant is attenuated in mice [Ref6684:Taylor et al., 1987]. |
2883655
|
|
|
ctxA from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136023
|
|
147673805
|
VC0395_A1060 |
|
YP_001217006.1 |
cholera enterotoxin, A subunit |
Virulence factor |
TOXIN: Fluid accumulated in the rabbit intestinal loop model after 16 hours of incubation with cholera toxin, which is encoded by the genes ctxA and ctxB [Ref6685:Peterson and Ochoa, 1989]. |
2549637
|
|
|
carB from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136051
|
|
147673654
|
VC0395_A1967 |
|
YP_001217891.1 |
carbamoyl phosphate synthase large subunit |
Virulence factor |
MUTATION: carB mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
zot from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136175
|
|
147674144
|
VC0395_A1061 |
|
YP_001217007.1 |
zona occludens toxin |
Virulence factor |
TOXIN: The zot toxin increases the permeability of the small intestinal mucosa by affecting the structure of the intercellular tight junction, or zonula occludens [Ref6686:Fasano et al., 1991]. |
2052603
|
|
|
gshB from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136329
|
|
147673886
|
VC0395_A0020 |
|
YP_001215994.1 |
glutathione synthetase |
Virulence factor |
MUTATION: gshB mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
nqrE from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136378
|
|
147674521
|
VC0395_A1880 |
|
YP_001217804.1 |
Na(+)-translocating NADH-quinone reductase subunit E |
Virulence factor |
MUTATION: nqrE mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
fabG from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136416
|
|
147675453
|
VC0395_A1607 |
|
YP_001217548.1 |
3-ketoacyl-(acyl-carrier-protein) reductase |
Virulence factor |
MUTATION: fabG mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
tcpN/toxT |
Vibrio cholerae O395 |
5136424
|
|
147673596
|
VC0395_A0363 |
|
YP_001216319.1 |
TCP pilus virulence regulatory protein |
Virulence factor |
MUTATION: toxT mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
purD from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136447
|
|
147673352
|
VC0395_A2652 |
|
YP_001218530.1 |
phosphoribosylamine--glycine ligase |
Virulence factor |
MUTATION: purD mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
rpoS from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136575
|
|
147674644
|
VC0395_A0062 |
|
YP_001216035.1 |
RNA polymerase sigma factor RpoS |
Virulence factor |
MUTATION: rpoS mutants had defective colonization ability of mice intestines compared to the wild type [Ref6687:Merrell et al., 2000]. |
11083783
|
|
|
trpG from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136631
|
|
147673994
|
VC0395_A0795 |
|
YP_001216745.1 |
anthranilate synthase component II |
Virulence factor |
MUTATION: trpG mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
purF from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136658
|
|
147673131
|
VC0395_A0525 |
|
YP_001216476.1 |
amidophosphoribosyltransferase |
Virulence factor |
MUTATION: purF mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
purL from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136680
|
|
147673351
|
VC0395_A0395 |
|
YP_001216350.1 |
phosphoribosylformylglycinamidine synthase |
Virulence factor |
MUTATION: purL mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
rpoE from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136709
|
|
147675349
|
VC0395_A2045 |
|
YP_001217969.1 |
RNA polymerase sigma factor RpoE |
Virulence factor |
MUTATION: rpoE mutant is attenuated in mice [Ref6688:Kovacikova and Skorupski, 2002]. |
12228259
|
|
|
relA |
Vibrio cholerae O395 |
5136723
|
|
147673921
|
VC0395_A2029 |
|
YP_001217953.1 |
GTP pyrophosphokinase |
Virulence factor |
MUTATION: relA mutant is attenuated in mice [Ref6689:Haralalka et al., 2003]. |
12896985
|
|
|
lysA from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136731
|
|
147674363
|
VC0395_A2394 |
|
YP_001218294.1 |
diaminopimelate decarboxylase |
Virulence factor |
MUTATION: lysA mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
aceF from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136758
|
|
147674758
|
VC0395_A1989 |
|
YP_001217913.1 |
dihydrolipoamide acetyltransferase |
Virulence factor |
MUTATION: aceF mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
tcpA from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136800
|
|
147673187
|
VC0395_A0353 |
|
YP_001216309.1 |
toxin co-regulated pilin |
Virulence factor |
MUTATION: tcpA mutant has defect in colonization of infant mice [Ref6690:Thelin and Taylor, 1996]. |
8698524
|
|
|
acfC from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136801
|
|
147673127
|
VC0395_A0366 |
|
YP_001216322.1 |
accessory colonization factor AcfC |
Virulence factor |
MUTATION: acfC mutant had a defect in colonization of mice, and had a ten-fold increase in the 50% lethal dose in mice [Ref6691:Peterson and Mekalanos, 1988]. |
2902009
|
|
|
rfbL from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136823
|
|
147673559
|
VC0395_A2629 |
|
YP_001218508.1 |
rfbL protein |
Virulence factor |
MUTATION: rfbL mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
nqrF from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136909
|
|
147675137
|
VC0395_A1879 |
|
YP_001217803.1 |
Na(+)-translocating NADH-quinone reductase subunit F |
Virulence factor |
MUTATION: nqrF mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
galM from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5136975
|
|
147675555
|
VC0395_A1196 |
|
YP_001217142.1 |
aldose 1-epimerase |
Virulence factor |
MUTATION: galM mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
recO from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5137028
|
|
147673381
|
VC0395_A2037 |
|
YP_001217961.1 |
DNA repair protein RecO |
Virulence factor |
MUTATION: recO mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
ilvD from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5137059
|
|
147675499
|
VC0395_A2491 |
|
YP_001218384.1 |
dihydroxy-acid dehydratase |
Virulence factor |
MUTATION: ilvD mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
deoC from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5137095
|
|
147674428
|
VC0395_A1929 |
|
YP_001217853.1 |
deoxyribose-phosphate aldolase |
Virulence factor |
MUTATION: deoC mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
acfB from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5137124
|
|
147673778
|
VC0395_A0365 |
|
YP_001216321.1 |
accessory colonization factor AcfB |
Virulence factor |
MUTATION: acfB mutant had a defect in colonization of mice, and had a ten-fold increase in the 50% lethal dose in mice [Ref6691:Peterson and Mekalanos, 1988]. |
2902009
|
|
|
purK from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5137360
|
|
147674298
|
VC0395_A2468 |
|
YP_001218361.1 |
phosphoribosylaminoimidazole carboxylase ATPase subunit |
Virulence factor |
MUTATION: purK mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
pta from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5137512
|
|
147675254
|
VC0395_A0615 |
|
YP_001216565.1 |
phosphate acetyltransferase |
Virulence factor |
MUTATION: pta mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
acfA from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5137546
|
|
147674631
|
VC0395_A0368 |
|
YP_001216324.1 |
accessory colonization factor AcfA |
Virulence factor |
MUTATION: acfA mutant had a defect in colonization of mice, and had a ten-fold increase in the 50% lethal dose in mice [Ref6691:Peterson and Mekalanos, 1988]. |
2902009
|
|
|
galK from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5137652
|
|
147673567
|
VC0395_A1197 |
|
YP_001217143.1 |
galactokinase |
Virulence factor |
MUTATION: galK mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
carA from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5137723
|
|
147675544
|
VC0395_A1968 |
|
YP_001217892.1 |
carbamoyl phosphate synthase small subunit |
Virulence factor |
MUTATION: carA mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
sspA from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5137829
|
|
147675668
|
VC0395_A0108 |
|
YP_001216073.1 |
stringent starvation protein A |
Virulence factor |
MUTATION: sspA mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
bioB from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5137832
|
|
147673516
|
VC0395_A0630 |
|
YP_001216580.1 |
biotin synthase |
Virulence factor |
MUTATION: bioB mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
irgA |
Vibrio cholerae O395 |
5137888
|
|
147674899
|
VC0395_A0028 |
|
YP_001216002.1 |
enterobactin receptor |
Virulence factor |
MUTATION: irgA mutant is attenuated in mice [Ref6692:Goldberg et al., 1990]. |
2152889
|
|
|
tcpE from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5137918
|
|
147675450
|
VC0395_A0361 |
|
YP_001216317.1 |
toxin co-regulated pilus biosynthesis protein E |
Virulence factor |
MUTATION: tcpE mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
zwf from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5133978
|
|
147671692
|
VC0395_0341 |
|
YP_001215182.1 |
glucose-6-phosphate 1-dehydrogenase |
Virulence factor |
MUTATION: zwf mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
ydbK from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5133989
|
|
147672240
|
VC0395_0463 |
|
YP_001215304.1 |
pyruvate-flavoredoxin oxidoreductase |
Virulence factor |
MUTATION: ydbK mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
ace from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5134229
|
|
147672404
|
VC0395_0510 |
|
YP_001215349.1 |
accessory cholera enterotoxin |
Virulence factor |
TOXIN: Ace increases short-circuit current in Ussing chambers and causes fluid secretion in ligated rabbit ileal loops [Ref6682:Trucksis et al., 1993]. |
8389476
|
|
|
zot from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5134487
|
|
147672022
|
VC0395_0511 |
|
YP_001215350.1 |
zona occludens toxin |
Virulence factor |
TOXIN: The zot toxin increases the permeability of the small intestinal mucosa by affecting the structure of the intercellular tight junction, or zonula occludens [Ref6686:Fasano et al., 1991]. |
2052603
|
|
|
phaC from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5134754
|
|
147671535
|
VC0395_0628 |
|
YP_001215467.1 |
polyhydroxyalkanoic acid synthase |
Virulence factor |
MUTATION: phaC mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
ctxA from Vibrio cholerae O395 |
Vibrio cholerae O395 |
5134988
|
|
147672109
|
VC0395_0512 |
|
YP_001215351.1 |
cholera enterotoxin, A subunit |
Virulence factor |
TOXIN: Fluid accumulated in the rabbit intestinal loop model after 16 hours of incubation with cholera toxin, which is encoded by the genes ctxA and ctxB [Ref6685:Peterson and Ochoa, 1989]. |
2549637
|
|
|
VCA0688 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612154
|
|
15601445
|
VCA0688 |
AE003853 |
NP_233076 |
polyhydroxyalkanoic acid synthase |
Virulence factor |
MUTATION: VCA0688 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VCA0910 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612226
|
|
15601664
|
VCA0910 |
AE003853 |
NP_233295 |
tonB1 protein |
Virulence factor |
MUTATION: VCA0910 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VCA0006 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612229
|
|
15600777
|
VCA0006 |
AE003853 |
NP_232407 |
hypothetical protein |
Virulence factor |
MUTATION: VCA0006 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VCA0903 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612274
|
|
15601657
|
VCA0903 |
AE003853 |
NP_233288 |
hypothetical protein |
Virulence factor |
MUTATION: VCA0903 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VCA0896 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612623
|
|
15601650
|
VCA0896 |
AE003853 |
NP_233281 |
glucose-6-phosphate 1-dehydrogenase |
Virulence factor |
MUTATION: VCA0896 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VCA0600 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612672
|
|
15601358
|
VCA0600 |
AE003853 |
NP_232989 |
repressor protein PhnR, putative |
Virulence factor |
MUTATION: VCA0600 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VCA0578 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612692
|
|
15601337
|
VCA0578 |
AE003853 |
NP_232968 |
hypothetical protein |
Virulence factor |
MUTATION: VCA0578 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VCA0530 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612700
|
|
15601290
|
VCA0530 |
AE003853 |
NP_232921 |
pyruvate-flavoredoxin oxidoreductase |
Virulence factor |
MUTATION: VCA0530 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VCA0583 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612870
|
|
15601342
|
VCA0583 |
AE003853 |
NP_232973 |
hypothetical protein |
Virulence factor |
MUTATION: VCA0583 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VCA0930 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612901
|
|
15601684
|
VCA0930 |
AE003853 |
NP_233315 |
hypothetical protein |
Virulence factor |
MUTATION: VCA0930 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0028 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612960
|
|
15640060
|
VC0028 |
AE003852 |
NP_229687 |
dihydroxy-acid dehydratase |
Virulence factor |
MUTATION: VC0028 mutant was attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
cyaA from Vibrio cholerae O1 biovar El Tor str. N16961 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612962
|
|
15640154
|
VC0122 |
|
NP_229781.1 |
adenylate cyclase |
Virulence factor |
MUTATION: cyaA mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC2426 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612968
|
|
15642423
|
VC2426 |
HB973679 |
NP_232056 |
leader peptidase PilD |
Virulence factor |
MUTATION: VC2426 (pilD/vcpD) mutant is attenuated in mice [Ref6693:Marsh and Taylor, 1998]. |
9781884
|
|
|
VC2433 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612975
|
|
15642430
|
VC2433 |
AE003852 |
NP_232063 |
cyclic 3',5'-adenosine monophosphate phosphodiesterase |
Virulence factor |
MUTATION: VC2433 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
tolC |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612978
|
|
15642433
|
VC2436 |
|
NP_232066.1 |
outer membrane channel protein |
Virulence factor |
MUTATION: tolC mutant is deficient in intestinal colonization of mice [Ref6694:Bina and Mekalanos, 2001]. |
11402016
|
|
|
VC2437 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612979
|
|
0
|
VC2437 |
|
- |
- |
Virulence factor |
MUTATION: VC2437 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC2453 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612995
|
|
15642449
|
VC2453 |
AE003852 |
NP_232082 |
hybrid sensory histidine kinase BarA |
Virulence factor |
MUTATION: barA mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC2455 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612997
|
|
15642451
|
VC2455 |
AE003852 |
NP_232084 |
hypothetical protein |
Virulence factor |
MUTATION: VC2455 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
acpS from Vibrio cholerae O1 biovar El Tor str. N16961 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2612999
|
|
15642453
|
VC2457 |
|
NP_232086.1 |
4'-phosphopantetheinyl transferase |
Virulence factor |
MUTATION: acpS mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
recO from Vibrio cholerae O1 biovar El Tor str. N16961 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613001
|
|
15642455
|
VC2459 |
|
NP_232088.1 |
DNA repair protein RecO |
Virulence factor |
MUTATION: recO mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
carB from Vibrio cholerae O1 biovar El Tor str. N16961 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613058
|
|
15642386
|
VC2389 |
|
NP_232019.1 |
carbamoyl phosphate synthase large subunit |
Virulence factor |
MUTATION: carB mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC2390 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613059
|
|
15642387
|
VC2390 |
AE003852 |
NP_232020 |
carbamoyl phosphate synthase small subunit |
Virulence factor |
MUTATION: VC2390 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
aceF from Vibrio cholerae O1 biovar El Tor str. N16961 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613082
|
|
15642410
|
VC2413 |
|
NP_232043.1 |
dihydrolipoamide acetyltransferase |
Virulence factor |
MUTATION: aceF mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC2295 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613091
|
|
15642293
|
VC2295 |
AE003852 |
NP_231926 |
Na(+)-translocating NADH-quinone reductase subunit A |
Virulence factor |
MUTATION: VC2295 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC2320 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613116
|
|
15642318
|
VC2320 |
AE003852 |
NP_231951 |
exodeoxyribonuclease V, 135 kDa subunit |
Virulence factor |
MUTATION: VC2320 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC2290 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613212
|
|
15642288
|
VC2290 |
AE003852 |
NP_231921 |
Na(+)-translocating NADH-quinone reductase subunit F |
Virulence factor |
MUTATION: VC2290 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC2291 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613213
|
|
15642289
|
VC2291 |
AE003852 |
NP_231922 |
Na(+)-translocating NADH-quinone reductase subunit E |
Virulence factor |
MUTATION: VC2291 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC2206 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613246
|
|
15642205
|
VC2206 |
AE003852 |
NP_231837 |
hypothetical protein |
Virulence factor |
MUTATION: VC2206 (flgP) mutant is defective in intestinal colonization of mice [Ref6695:Morris et al., 2008]. |
17981980
|
|
|
fur from Vibrio cholerae O1 biovar El Tor str. N16961 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613362
|
|
15642106
|
VC2106 |
|
NP_231738.1 |
ferric uptake regulator |
Virulence factor |
MUTATION: fur mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
fabG from Vibrio cholerae O1 biovar El Tor str. N16961 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613400
|
|
15642023
|
VC2021 |
|
NP_231655.1 |
3-ketoacyl-(acyl-carrier-protein) reductase |
Virulence factor |
MUTATION: fabG mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC2030 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613409
|
|
15642032
|
VC2030 |
AE003852 |
NP_231664 |
ribonuclease E |
Virulence factor |
MUTATION: VC2030 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC2042 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613423
|
|
15642044
|
VC2042 |
AE003852 |
NP_231676 |
histone deacetylase/AcuC/AphA family protein |
Virulence factor |
MUTATION: aphA mutant is attenuated in mice [Ref6696:Kovacikova and Skorupski, 2001]. |
11489126
|
|
|
VC2052 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613432
|
|
15642052
|
VC2052 |
AE003852 |
NP_231684 |
cytochrome c-type biogenesis protein CcmF |
Virulence factor |
MUTATION: VC2052 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC2067 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613447
|
|
15642067
|
VC2067 |
AE003852 |
NP_231699 |
MinD-related protein |
Virulence factor |
MUTATION: VC2067 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
tolB from Vibrio cholerae O1 biovar El Tor str. N16961 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613590
|
|
15641838
|
VC1836 |
|
NP_231470.1 |
translocation protein TolB |
Virulence factor |
MUTATION: tolB mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC1887 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613641
|
|
15641889
|
VC1887 |
AE003852 |
NP_231521 |
hypothetical protein |
Virulence factor |
MUTATION: VC1887 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC1771 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613651
|
|
15641774
|
VC1771 |
AE003852 |
NP_231406 |
hypothetical protein |
Virulence factor |
MUTATION: VC1771 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
mukB from Vibrio cholerae O1 biovar El Tor str. N16961 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613719
|
|
15641718
|
VC1714 |
|
NP_231350.1 |
cell division protein MukB |
Virulence factor |
MUTATION: mukB mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC1715 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613720
|
|
15641719
|
VC1715 |
AE003852 |
NP_231351 |
condesin subunit E |
Virulence factor |
MUTATION: VC1715 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC1716 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613721
|
|
15641720
|
VC1716 |
AE003852 |
NP_231352 |
condesin subunit F |
Virulence factor |
MUTATION: VC1716 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC1639 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613770
|
|
15641644
|
VC1639 |
AE003852 |
NP_231276 |
sensor histidine kinase |
Virulence factor |
MUTATION: VC1639 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC1675 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613806
|
|
15641679
|
VC1675 |
AE003852 |
NP_231311 |
multidrug resistance protein, putative |
Virulence factor |
MUTATION: VC1675 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
galM from Vibrio cholerae O1 biovar El Tor str. N16961 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613848
|
|
15641602
|
VC1594 |
|
NP_231234.1 |
aldose 1-epimerase |
Virulence factor |
MUTATION: galM mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC1595 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2613849
|
|
15641603
|
VC1595 |
AE003852 |
NP_231235 |
galactokinase |
Virulence factor |
MUTATION: VC1595 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0257 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614180
|
|
15640286
|
VC0257 |
AE003853 |
NP_229913 |
transposase OrfAB, subunit B |
Virulence factor |
MUTATION: VC0257 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0965 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614218
|
|
15640981
|
VC0965 |
AE003852 |
NP_230612 |
phosphoenolpyruvate-protein phosphotransferase |
Virulence factor |
MUTATION: VC0965 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC1004 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614257
|
|
15641019
|
VC1004 |
AE003852 |
NP_230650 |
amidophosphoribosyltransferase |
Virulence factor |
MUTATION: VC1004 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC1012 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614265
|
|
15641027
|
VC1012 |
AE003852 |
NP_230658 |
electron transport complex RsxE subunit |
Virulence factor |
MUTATION: VC1012 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0251 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614274
|
|
15640281
|
VC0251 |
AE003852 |
NP_229908 |
acyl protein synthase/acyl-CoA reductase RfbN |
Virulence factor |
MUTATION: VC0251 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0249 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614277
|
|
15640279
|
VC0249 |
AE003852 |
NP_229906 |
rfbL protein |
Virulence factor |
MUTATION: rfbL mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0250 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614278
|
|
15640280
|
VC0250 |
AE003852 |
NP_229907 |
iron-containing alcohol dehydrogenase family protein RfbM |
Virulence factor |
MUTATION: VC0250 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC1021 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614291
|
|
15641034
|
VC1021 |
AE003852 |
NP_230666 |
LuxO repressor protein |
Virulence factor |
MUTATION: luxO mutant is defective in colonization of infant mouse intestine [Ref6697:Zhu et al., 2002]. |
11854465
|
|
|
VC1075 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614345
|
|
15641088
|
VC1075 |
AE003852 |
NP_230720 |
hypothetical protein |
Virulence factor |
MUTATION: VC1075 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC1098 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614368
|
|
15641111
|
VC1098 |
AE003852 |
NP_230743 |
acetate kinase |
Virulence factor |
MUTATION: VC1098 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0051 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614419
|
|
15640083
|
VC0051 |
AE003852 |
NP_229710 |
phosphoribosylaminoimidazole carboxylase ATPase subunit |
Virulence factor |
MUTATION: VC0051 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0032 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614466
|
|
15640064
|
VC0032 |
AE003852 |
NP_229691 |
ComM-related protein |
Virulence factor |
MUTATION: VC0032 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0036 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614481
|
|
15640068
|
VC0036 |
AE003852 |
NP_229695 |
FixG-related protein |
Virulence factor |
MUTATION: VC0036 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0826 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614493
|
|
15640843
|
VC0826 |
AE003852 |
NP_230474 |
toxin co-regulated pilus biosynthesis protein P |
Virulence factor |
MUTATION: tcpP mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0828 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614495
|
|
15640845
|
VC0828 |
AE003852 |
NP_230476 |
toxin co-regulated pilin |
Virulence factor |
MUTATION: VC0828 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0831 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614498
|
|
15640848
|
VC0831 |
AE003852 |
NP_230479 |
toxin co-regulated pilus biosynthesis outer membrane protein C |
Virulence factor |
MUTATION: VC0831 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0835 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614502
|
|
15640852
|
VC0835 |
AE003852 |
NP_230483 |
toxin co-regulated pilus biosynthesis protein T |
Virulence factor |
MUTATION: VC0835 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0836 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614503
|
|
15640853
|
VC0836 |
AE003852 |
NP_230484 |
toxin co-regulated pilus biosynthesis protein E |
Virulence factor |
MUTATION: tcpE mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0837 |
Vibrio |
2614504
|
|
15640854
|
VC0837 |
|
NP_230485.1 |
toxin co-regulated pilus biosynthesis protein F |
Virulence factor |
MUTATION: tcpF mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0869 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614536
|
|
15640885
|
VC0869 |
AE003852 |
NP_230516 |
phosphoribosylformylglycinamidine synthase |
Virulence factor |
MUTATION: VC0869 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0247 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614565
|
|
15640277
|
VC0247 |
AE003852 |
NP_229904 |
lipopolysaccharide/O-antigen transport protein |
Virulence factor |
MUTATION: VC0247 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0244 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614566
|
|
15640274
|
VC0244 |
AE003852 |
NP_229901 |
perosamine synthase |
Virulence factor |
MUTATION: VC0244 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC1162 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614595
|
|
15641175
|
VC1162 |
AE003852 |
NP_230807 |
hypothetical protein |
Virulence factor |
MUTATION: VC1162 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC1173 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614606
|
|
15641186
|
VC1173 |
AE003852 |
NP_230818 |
anthranilate synthase component II |
Virulence factor |
MUTATION: VC1173 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0192 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614701
|
|
15640222
|
VC0192 |
AE003852 |
NP_229849 |
AraC/XylS family transcriptional regulator |
Virulence factor |
MUTATION: VC0192 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0212 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614702
|
|
15640242
|
VC0212 |
HB970497 |
NP_229869 |
lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase |
Virulence factor |
MUTATION: VC0212 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0242 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614705
|
|
15640272
|
VC0242 |
AE003852 |
NP_229899 |
phosphomannomutase |
Virulence factor |
MUTATION: VC0242 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0243 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614706
|
|
15640273
|
VC0243 |
AE003852 |
NP_229900 |
GDP-mannose 4,6-dehydratase |
Virulence factor |
MUTATION: VC0243 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0239 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614707
|
|
15640269
|
VC0239 |
AE003852 |
NP_229896 |
hypothetical protein |
Virulence factor |
MUTATION: VC0239 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC1380 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614834
|
|
15641392
|
VC1380 |
AE003852 |
NP_231024 |
hypothetical protein |
Virulence factor |
MUTATION: VC1380 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0238 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614849
|
|
15640268
|
VC0238 |
AE003852 |
NP_229895 |
hexapaptide repeat-containing transferase |
Virulence factor |
MUTATION: VC0238 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0260 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2614878
|
|
15640289
|
VC0260 |
AE003852 |
NP_229916 |
mannosyl-transferase |
Virulence factor |
MUTATION: VC0260 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
hfq |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615060
|
|
15640374
|
VC0347 |
|
NP_230001.1 |
RNA-binding protein Hfq |
Virulence factor |
MUTATION: hfq mutant fails to colonize the suckling mouse intestine [Ref6698:Ding et al., 2004]. |
15225327
|
|
|
VC0459 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615121
|
|
15640486
|
VC0459 |
AE003852 |
NP_230113 |
hypothetical protein |
Virulence factor |
MUTATION: VC0459 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0468 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615130
|
|
15640495
|
VC0468 |
AE003852 |
NP_230122 |
glutathione synthetase |
Virulence factor |
MUTATION: VC0468 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC2506 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615170
|
|
15642502
|
VC2506 |
AE003852 |
NP_232135 |
ATP-dependent helicase HepA |
Virulence factor |
MUTATION: VC2506 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
sspA from Vibrio cholerae O1 biovar El Tor str. N16961 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615253
|
|
15640598
|
VC0576 |
|
NP_230227.1 |
stringent starvation protein A |
Virulence factor |
MUTATION: sspA mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0259 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615261
|
|
15640288
|
VC0259 |
AE003852 |
NP_229915 |
lipopolysaccharide biosynthesis protein RfbV |
Virulence factor |
MUTATION: VC0259 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0485 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615279
|
|
15640512
|
VC0485 |
AE003852 |
NP_230139 |
pyruvate kinase |
Virulence factor |
MUTATION: VC0485 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0125 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615366
|
|
15640156
|
VC0125 |
AE003852 |
NP_229783 |
diaminopimelate decarboxylase |
Virulence factor |
MUTATION: VC0125 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0596 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615384
|
|
15640617
|
VC0596 |
AE003852 |
NP_230246 |
dnaK suppressor protein |
Virulence factor |
MUTATION: VC0596 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
glmM |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615427
|
|
15640659
|
VC0639 |
AE003852 |
NP_230288 |
phosphoglucosamine mutase |
Virulence factor |
MUTATION: VC0639 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0647 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615437
|
|
15640667
|
VC0647 |
AE003852 |
NP_230296 |
polynucleotide phosphorylase/polyadenylase |
Virulence factor |
MUTATION: VC0647 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC2544 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615561
|
|
15642539
|
VC2544 |
AE003852 |
NP_232172 |
fructose-1,6-bisphosphatase |
Virulence factor |
MUTATION: VC2544 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC2647 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615664
|
|
15642642
|
VC2647 |
AE003852 |
NP_232275 |
hypothetical protein |
Virulence factor |
MUTATION: VC2347 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC2658 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615675
|
|
15642653
|
VC2658 |
AE003852 |
NP_232286 |
fumarate reductase subunit C |
Virulence factor |
MUTATION: VC2658 mutant is attenuated in mice |
|
|
|
VC2660 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615677
|
|
15642655
|
VC2660 |
AE003852 |
NP_232288 |
elongation factor P |
Virulence factor |
MUTATION: VC2660 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0724 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615733
|
|
15640743
|
VC0724 |
AE003852 |
NP_230373 |
phosphate ABC transporter, permease protein |
Virulence factor |
MUTATION: VC0724 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0727 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615736
|
|
15640746
|
VC0727 |
AE003852 |
NP_230376 |
transcriptional regulator PhoU |
Virulence factor |
MUTATION: phoU mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0523 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615814
|
|
15640545
|
VC0523 |
AE003852 |
NP_230174 |
putative glycerol-3-phosphate acyltransferase PlsY |
Virulence factor |
MUTATION: VC0523 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0095 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615822
|
|
15640127
|
VC0095 |
AE003852 |
NP_229754 |
chorismate--pyruvate lyase |
Virulence factor |
MUTATION: VC0095 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
VC0132 |
Vibrio cholerae O1 biovar El Tor str. N16961 |
2615825
|
|
15640163
|
VC0132 |
AE003852 |
NP_229790 |
hypothetical protein |
Virulence factor |
MUTATION: VC0132 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
ilvD from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7771326
|
|
227080265
|
VCM66_0028 |
|
YP_002808816.1 |
dihydroxy-acid dehydratase |
Virulence factor |
MUTATION: ilvD mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
purK from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7771349
|
|
227080288
|
VCM66_0051 |
|
YP_002808839.1 |
phosphoribosylaminoimidazole carboxylase, ATPase subunit |
Virulence factor |
MUTATION: purK mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
ubiC from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7771392
|
|
227080331
|
VCM66_0095 |
|
YP_002808882.1 |
chorismate-pyruvate lyase |
Virulence factor |
MUTATION: ubiC mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
cyaA from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7771419
|
|
227080358
|
VCM66_0122 |
|
YP_002808909.1 |
adenylate cyclase |
Virulence factor |
MUTATION: cyaA mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
lysA from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7771422
|
|
227080361
|
VCM66_0125 |
|
YP_002808912.1 |
diaminopimelate decarboxylase |
Virulence factor |
MUTATION: lysA mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
rfbB from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7771522
|
|
227080461
|
VCM66_0230 |
|
YP_002809012.1 |
phosphomannomutase |
Virulence factor |
MUTATION: rfbB mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
rfbL from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7771529
|
|
227080468
|
VCM66_0237 |
|
YP_002809019.1 |
rfbL protein |
Virulence factor |
MUTATION: rfbL mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
purD from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7771550
|
|
227080489
|
VCM66_0260 |
|
YP_002809040.1 |
phosphoribosylamine-glycine ligase |
Virulence factor |
MUTATION: purD mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
gshB from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7771739
|
|
227080678
|
VCM66_0453 |
|
YP_002809229.1 |
glutathione synthetase |
Virulence factor |
MUTATION: gshB mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
pykF from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7771756
|
|
227080695
|
VCM66_0470 |
|
YP_002809246.1 |
pyruvate kinase I |
Virulence factor |
MUTATION: pykF mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
rpoS from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7771778
|
|
227080717
|
VCM66_0492 |
|
YP_002809268.1 |
RNA polymerase sigma factor RpoS |
Virulence factor |
MUTATION: rpoS mutants are defective in colonization of mouse intestines compared to the wild type [Ref6687:Merrell et al., 2000]. |
11083783
|
|
|
sspA from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7771820
|
|
227080759
|
VCM66_0534 |
|
YP_002809310.1 |
stringent starvation protein A |
Virulence factor |
MUTATION: sspA mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
tcpA from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7772066
|
|
227081005
|
VCM66_0785 |
|
YP_002809556.1 |
toxin co-regulated pilin |
Virulence factor |
MUTATION: tcpA mutant is defective at colonizing infant mice [Ref6690:Thelin and Taylor, 1996]. |
8698524
|
|
|
tcpT from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7772073
|
|
227081012
|
VCM66_0792 |
|
YP_002809563.1 |
toxin co-regulated pilus biosynthesis protein T |
Virulence factor |
MUTATION: tcpT mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
tcpE from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7772074
|
|
227081013
|
VCM66_0793 |
|
YP_002809564.1 |
toxin co-regulated pilus biosynthesis protein E |
Virulence factor |
MUTATION: tcpE mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
acfB from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7772078
|
|
227081017
|
VCM66_0797 |
|
YP_002809568.1 |
accessory colonization factor AcfB |
Virulence factor |
MUTATION: acfB mutant had a defect in colonization of mice, and had a ten-fold increase in the 50% lethal dose in mice [Ref6691:Peterson and Mekalanos, 1988]. |
2902009
|
|
|
acfC from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7772079
|
|
227081018
|
VCM66_0798 |
|
YP_002809569.1 |
accessory colonization factor AcfC |
Virulence factor |
MUTATION: acfC mutant had a defect in colonization of mice, and had a ten-fold increase in the 50% lethal dose in mice [Ref6691:Peterson and Mekalanos, 1988]. |
2902009
|
|
|
acfA from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7772082
|
|
227081021
|
VCM66_0801 |
|
YP_002809572.1 |
accessory colonization factor AcfA |
Virulence factor |
MUTATION: acfA mutant had a defect in colonization of mice, and had a ten-fold increase in the 50% lethal dose in mice [Ref6691:Peterson and Mekalanos, 1988]. |
2902009
|
|
|
purL from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7772106
|
|
227081045
|
VCM66_0826 |
|
YP_002809596.1 |
phosphoribosylformylglycinamidine synthase |
Virulence factor |
MUTATION: purL mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
glyA-1 |
Vibrio cholerae M66-2 |
7772176
|
|
227081115
|
VCM66_0897 |
|
YP_002809666.1 |
serine hydroxymethyltransferase |
Virulence factor |
MUTATION: glyA-1 mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
purF from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7772239
|
|
227081178
|
VCM66_0960 |
|
YP_002809729.1 |
amidophosphoribosyltransferase |
Virulence factor |
MUTATION: purF mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
pta from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7772331
|
|
227081270
|
VCM66_1053 |
|
YP_002809821.1 |
phosphate acetyltransferase |
Virulence factor |
MUTATION: pta mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
bioB from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7772346
|
|
227081285
|
VCM66_1068 |
|
YP_002809836.1 |
biotin synthase |
Virulence factor |
MUTATION: bioB mutant is attenuated in mice [Ref6683:Chiang and Mekalanos, 1998]. |
9515705
|
|
|
trpG from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7772406
|
|
227081345
|
VCM66_1128 |
|
YP_002809896.1 |
anthranilate synthase component II |
Virulence factor |
MUTATION: trpG mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
rtxA |
Vibrio cholerae M66-2 |
7772684
|
|
227081623
|
VCM66_1407 |
|
YP_002810174.1 |
RTX toxin RtxA |
Virulence factor |
TOXIN: RTX toxin encoded by the rtxA gene, causes depolymerization of actin stress fibers and covalent cross-linking of cellular actin into dimers, trimers and higher multimers [Ref6842:Fullner and Mekalanos, 2000]. |
11032799
|
|
|
galM from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7772808
|
|
227081747
|
VCM66_1534 |
|
YP_002810298.1 |
aldose 1-epimerase |
Virulence factor |
MUTATION: galM mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
galK from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7772809
|
|
227081748
|
VCM66_1535 |
|
YP_002810299.1 |
galactokinase |
Virulence factor |
MUTATION: galK mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
mukB from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7772924
|
|
227081863
|
VCM66_1654 |
|
YP_002810414.1 |
cell division protein MukB |
Virulence factor |
MUTATION: mukB mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
tolB from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7773026
|
|
227081965
|
VCM66_1759 |
|
YP_002810516.1 |
tolB protein |
Virulence factor |
MUTATION: tolB mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
fabG from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7773209
|
|
227082148
|
VCM66_1945 |
|
YP_002810699.1 |
3-oxoacyl-(acyl-carrier-protein) reductase |
Virulence factor |
MUTATION: fabG mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
ccmF from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7773240
|
|
227082179
|
VCM66_1976 |
|
YP_002810730.1 |
cytochrome c-type biogenesis protein CcmF |
Virulence factor |
MUTATION: ccmF mutant is attenuated in mice [Ref6681:Merrell et al., 2002].
|
11952899
|
|
|
sucA |
Vibrio cholerae M66-2 |
7773274
|
|
227082213
|
VCM66_2011 |
|
YP_002810764.1 |
2-oxoglutarate dehydrogenase, E1 component |
Virulence factor |
MUTATION: sucA mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
fur from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7773292
|
|
227082231
|
VCM66_2029 |
|
YP_002810782.1 |
ferric uptake regulation protein |
Virulence factor |
MUTATION: fur mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
nqrF from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7773475
|
|
227082414
|
VCM66_2213 |
|
YP_002810965.1 |
NADH:ubiquinone oxidoreductase, Na translocating, beta subunit |
Virulence factor |
MUTATION: nqrF mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
nqrE from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7773476
|
|
227082415
|
VCM66_2214 |
|
YP_002810966.1 |
NADH:ubiquinone oxidoreductase, Na translocating, hydrophobic membrane protein NqrE |
Virulence factor |
MUTATION: nqrE mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
deoC from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7773535
|
|
227082474
|
VCM66_2273 |
|
YP_002811025.1 |
deoxyribose-phosphate aldolase |
Virulence factor |
MUTATION: deoC mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
carB from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7773573
|
|
227082512
|
VCM66_2312 |
|
YP_002811063.1 |
carbamoyl-phosphate synthase, large subunit |
Virulence factor |
MUTATION: carB mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
carA from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7773574
|
|
227082513
|
VCM66_2313 |
|
YP_002811064.1 |
carbamoyl-phosphate synthase, small subunit |
Virulence factor |
MUTATION: carA mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
aceF from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7773595
|
|
227082534
|
VCM66_2336 |
|
YP_002811085.1 |
pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase |
Virulence factor |
MUTATION: aceF mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
acpS from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7773639
|
|
227082578
|
VCM66_2380 |
|
YP_002811129.1 |
holo-(acyl-carrier-protein) synthase |
Virulence factor |
MUTATION: acpS mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
recO from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7773641
|
|
227082580
|
VCM66_2382 |
|
YP_002811131.1 |
DNA repair protein RecO |
Virulence factor |
MUTATION: recO mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
rpoE from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7773649
|
|
227082588
|
VCM66_2390 |
|
YP_002811139.1 |
RNA polymerase sigma-E factor |
Virulence factor |
MUTATION: rpoE mutant is attenuated in mice [Ref6688:Kovacikova and Skorupski, 2002]. |
12228259
|
|
|
fbp from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7773723
|
|
227082662
|
VCM66_2465 |
|
YP_002811213.1 |
fructose-1,6-bisphosphatase |
Virulence factor |
MUTATION: fbp mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
frdC from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7773835
|
|
227082774
|
VCM66_2578 |
|
YP_002811325.1 |
fumarate reductase, 15 kDa hydrophobic protein |
Virulence factor |
MUTATION: frdC mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
phaC from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7780871
|
|
227812255
|
VCM66_A0646 |
|
YP_002812265.1 |
polyhydroxyalkanoic acid synthase |
Virulence factor |
MUTATION: phaC mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
zwf from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7781079
|
|
227812462
|
VCM66_A0856 |
|
YP_002812472.1 |
glucose-6-phosphate 1-dehydrogenase |
Virulence factor |
MUTATION: zwf mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
ydbK from Vibrio cholerae M66-2 |
Vibrio cholerae M66-2 |
7781770
|
|
227812099
|
VCM66_A0489 |
|
YP_002812109.1 |
pyruvate-flavoredoxin oxidoreductase |
Virulence factor |
MUTATION: ydbK mutant is attenuated in mice [Ref6681:Merrell et al., 2002]. |
11952899
|
|
|
ctxB |
Vibrio cholerae O139 |
|
|
310833320
|
|
|
|
cholera toxin B subunit |
Virulence factor |
MUTATION: ctxB mutants have abolished toxicity [Ref7007:Jobling and Holmes, 1991].
|
1943708
|
|
|
hemA |
Vibrio cholerae Bengal |
|
|
12656010
|
|
|
|
glutamyl-tRNA reductase |
Virulence factor |
MUTATION: A hemA mutant is highly attenuated in mice and rabbits [Ref7357:Ravichandran et al., 2006]. |
16102875
|
