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tcpT from Vibrio cholerae O395

Victor ID 2341
Gene Name tcpT from Vibrio cholerae O395
Sequence Strain (Species/Organism) Vibrio cholerae O395
NCBI Gene ID 5135974
NCBI Protein GI 147673300
Locus Tag VC0395_A0360
Protein Accession YP_001216316.1
Taxonomy ID 345073
Chromosome No 2
Gene Starting Position 386894
Gene Ending Position 388405
Gene Strand (Orientation) +
Protein Name toxin co-regulated pilus biosynthesis protein T
DNA Sequence 
>gi|147673035:386894-388405 Vibrio cholerae O395 chromosome 2, complete sequence
GATGTCAATTGATATAAAGTATTTAAGTCGTATTGATATAGATCGTGAGGAGTTTTTCTTTAAAGACTCG
AGATTAATGTGTAAGAAATTCGATGAAGAGCGTGAGGTATTAACTCTTCTCGAATTCGATACAAAATTTC
GGGTCAATCTTCTGAAGAAAGATAAAGTTTATAAGTATTTCTTAGTTTCAGATGCAAATCATAAATTATT
AATAGCGAATCTTGTTACCGAGCAGCAAGCTAAAGACTTAAGTTTTATAGAAAAAGATATAATGAAAATT
GCATCATCTGCTACAGCTTATGGTGCAAGTGACATCCACTTCATCCGAGAGGATAGGATTTGTAAAATAA
AATTCCGTGTGAATGGCACAATGATCGACTATAGAGAAATATTAAGTTCAGAAGCCGATTCGCTAATGTT
TGTTCTATACAATGTGATGGCAACAACGAAAGAAACGACGTGGAACCGAAAACTACCTCAAGATGCAAAT
ATTATTCTTGTGATCAACGAAAAGGCATATCGCTTTCGTTACGCACATATGCCTTTATTTGGTGAGGGAG
GGAAAAACTATCATGCGGTAGTTCGTATTATCTATCCTTCAAATAATTTTGTTTGTACAAACTATCAAGA
TATTGGGTATAACGAGGCTGATACCGATGCGATTGCAAGAATTCTAAATACATCTTATGGATTGTTCATT
GTTTCCGGAACAACAGGTTCTGGTAAATCAACATCTTTGAAAAAGTATATAGAATTACTTTTCTTTAATA
AATATAAGGGAAAAGGATGTTTTGTCACCGTTGAAGATCCTGTCGAGTATTTAATTTCTGGAGCACAGCA
AAGCTCAATTGTTGCCGATAATGATGATAAAACAAAGAACCCATTTGCTGATGCGGTACGTTCAGCGATG
CGTCGAGATCCGGACGTTATTATGATCGGTGAAATTCGTGATAAACCTACCGTTGAGGCTCTATCAAGTG
CTGTAGAAAGTGGCCACTATTGTCTTACGACCATCCATGCAGGTTCTGTTGTTTCTGTTTTACAAAGACT
TTCAGGATTAGGGATGAAGGCTGACAAAATAGCATCACCTGGATTTCTGGCTGGTATTACAAGTCAGAAA
TTAATTCCCGAACTTTGCCCAAGTTGTAAAGTTTCCTTTGTTGATGAACGTTATCAGCGTGCTGTATTTA
GCGCGAATGAAAATGGCTGTGAGGCATGTAATCATTCTGGGTTTAAAGGAAGGCTGCTTTTATTAGAAAC
ATTAGTCCCAACAGTTGAAGATTTAGAGCTAGTGGCGAGTGAAAACTGGGTTTCCCTTTATCGTAAATAT
CGGGAGCGACGCTTTATAAAAACTGGAAAAAAAGGTCTTGGTGAAGGCTTCAGCATTAAAGATAAAGCTT
ATTACAATGTTTTAAAAGGTAAAGTGTGTCACGAATATTTTATGCTGCATTTCGGTCAGTTAGATCATGA
GGATGAAAATATAATATATGAAAATTATCTCCAAGAAGTATA
Protein Sequence 
>gi|147673300|ref|YP_001216316.1| toxin co-regulated pilus biosynthesis protein T [Vibrio cholerae O395] MSIDIKYLSRIDIDREEFFFKDSRLMCKKFDEEREVLTLLEFDTKFRVNLLKKDKVYKYFLVSDANHKLLIANLVTEQQAKDLSFIEKDIMKIASSATAYGASDIHFIREDRICKIKFRVNGTMIDYREILSSEADSLMFVLYNVMATTKETTWNRKLPQDANIILVINEKAYRFRYAHMPLFGEGGKNYHAVVRIIYPSNNFVCTNYQDIGYNEADTDAIARILNTSYGLFIVSGTTGSGKSTSLKKYIELLFFNKYKGKGCFVTVEDPVEYLISGAQQSSIVADNDDKTKNPFADAVRSAMRRDPDVIMIGEIRDKPTVEALSSAVESGHYCLTTIHAGSVVSVLQRLSGLGMKADKIASPGFLAGITSQKLIPELCPSCKVSFVDERYQRAVFSANENGCEACNHSGFKGRLLLLETLVPTVEDLELVASENWVSLYRKYRERRFIKTGKKGLGEGFSIKDKAYYNVLKGKVCHEYFMLHFGQLDHEDENIIYENYLQEV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: tcpT mutant is attenuated in mice (Chiang and Mekalanos, 1998).
COG COG2804NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Chiang and Mekalanos, 1998: Chiang SL, Mekalanos JJ. Use of signature-tagged transposon mutagenesis to identify Vibrio cholerae genes critical for colonization. Molecular microbiology. 1998; 27(4); 797-805. [PubMed: 9515705].