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VC2290

Victor ID 2408
Gene Name VC2290
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2613212
NCBI Protein GI 15642288
Locus Tag VC2290
Genbank Accession AE003852
Protein Accession NP_231921
Other Database IDs UniProtKB-ID: NQRF_VIBCH
UniRef100: UniRef100_A5F5Y4
UniRef90: UniRef90_A5F5Y4
UniRef50: UniRef50_Q4FPV2
UniParc: UPI0000130470
EMBL: AF117331
EMBL: AE003852
EMBL-CDS: AAD29967.1
EMBL-CDS: AAF95434.1
RefSeq_NT: NC_002505.1
GenomeReviews: AE003852_GR
KEGG: vch:VC2290
TIGR: VC_2290
HOGENOM: HBG680293
OMA: VQLECPP
ProtClustDB: PRK05464
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 2444922
Gene Ending Position 2446148
Gene Strand (Orientation) -
Protein Name Na(+)-translocating NADH-quinone reductase subunit F
Protein pI 4.73
Protein Weight 42585.28
Protein Length 408
Protein Note uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm
DNA Sequence 
>gi|15640032:2444922-2446148 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
ATTAACCACCGAAGTCATCCAGTAGGATGTTTTCCTCTTCTACACCTAGGTTTTTCAGCATGTTGATCAC
TGCCGCGTTCATCATCGGAGGTCCACACATGTAGTATTCACAATCTTCCGGAGCTTCGTGATCCTTCAGA
TAGTTTTCATACAGTACGTTATGGATGAAACCGGTGTAGCCTGTCCAGTTATCTTCTGGTTGAGGATCTG
ACAGAGCACAGTGCCATACGAAGTTGTCATTCTCAGCCGCTAGGCCATCGAAATCTTCCACGTAGAACAT
TTCACGCTTAGAACGCGCACCGTACCAATAAGACATCTTACGCTTAGACTTCAGACGCTTCAGTTGGTCA
AAGATATGCGAACGCATTGGCGCCATACCCGCACCACCACCGATAAATACCATCTCTGCATCCGTGTCTT
TCGCGAAGAACTCACCGAACGGACCAGAAATCGTACATTTATCACCGGCTTTCAGTGACCAGATGTAAGA
AGACATTTGGCCTGGTGGCACATTTGGATTATTTGGCGGCGGAGTCGCGATACGCACGTTCAGCATGATG
ATGCCAAACTCTTCAGGGTAGTTCGCCATTGAGTATGCACGGATGATTGGCTCATCCACTTTAGACTCAT
AACGGAACAGATTGAATTTGTCCCAGTCACCACGGTATTTCTCAGGTACATCAAAATCGGCGTACTTAAC
ATGGTGCGCAGGCGCTTCAATCTGAATGTAACCACCCGCACGGAATGGTACTGATTCACCATCAGGAATC
GCAAGCTTCAGCTCTTTGATGAAAGTGGCTTTGTTATCGTTAGAGATAACCGTACATTCCCACTTCTTCA
CGCCAAAGATCTCTTCTGGCAGTTCCAGATCCATATCTGCTTTTACAGCAACCTGACACGCCAAACGCTC
ACCTTCACGGGCTTCGCCTTTGCTGATGTGATCCAGTTCTGTCGGCAGAATATCACCGCCACCTGATTTG
ATTTTTACACGGCATTGGCCACATGAACCACCACCACCACAAGCTGAAGATACGAATACACCAGCGCCTG
CCAGTGCAGTCAGCAACTTACCACCCGGTTGGGTTACGATCGCTTTTTCAGGATCGCCATTAATAGAAAT
TGTAATGTCACCTGTTGGTACTAGCTTGGATTTGGCGAACAGAATCACCAGAACCAAAGCCAGTATAATC
AGGGTAAACATCACTACACCAAAAATAATAGTAGACA
Protein Sequence 
>gi|15642288|ref|NP_231921.1| Na(+)-translocating NADH-quinone reductase subunit F [Vibrio cholerae O1 biovar El Tor str. N16961]
MSTIIFGVVMFTLIILALVLVILFAKSKLVPTGDITISINGDPEKAIVTQPGGKLLTALAGAGVFVSSAC
GGGGSCGQCRVKIKSGGGDILPTELDHISKGEAREGERLACQVAVKADMDLELPEEIFGVKKWECTVISN
DNKATFIKELKLAIPDGESVPFRAGGYIQIEAPAHHVKYADFDVPEKYRGDWDKFNLFRYESKVDEPIIR
AYSMANYPEEFGIIMLNVRIATPPPNNPNVPPGQMSSYIWSLKAGDKCTISGPFGEFFAKDTDAEMVFIG
GGAGMAPMRSHIFDQLKRLKSKRKMSYWYGARSKREMFYVEDFDGLAAENDNFVWHCALSDPQPEDNWTG
YTGFIHNVLYENYLKDHEAPEDCEYYMCGPPMMNAAVINMLKNLGVEEENILLDDFGG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC2290 mutant is attenuated in mice (Merrell et al., 2002).
COG COG2871C, under C: Energy production and conversion
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].