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ilvD from Vibrio cholerae M66-2

Victor ID 3841
Gene Name ilvD from Vibrio cholerae M66-2
Sequence Strain (Species/Organism) Vibrio cholerae M66-2
NCBI Gene ID 7771326
NCBI Protein GI 227080265
Locus Tag VCM66_0028
Protein Accession YP_002808816.1
Other Database IDs UniProtKB-ID: ILVD_VIBCM
UniRef100: UniRef100_A5F497
UniRef90: UniRef90_A5F497
UniRef50: UniRef50_Q5F8G6
UniParc: UPI000012D594
EMBL: CP001233
EMBL-CDS: ACP04365.1
RefSeq_NT: NC_012578.1
GenomeReviews: CP001233_GR
KEGG: vcm:VCM66_0028
OMA: KVPCLSK
ProtClustDB: PRK12448
Taxonomy ID 579112
Chromosome No I
Gene Starting Position 24791
Gene Ending Position 26632
Gene Strand (Orientation) -
Protein Name dihydroxy-acid dehydratase
DNA Sequence 
>gi|227080237:24791-26632 Vibrio cholerae M66-2 chromosome I, complete genome
CTTAGCCCTCAAGTTTGGACTTATCGCGCACTGCACCTTTGTCGGCGCTGGTTGCCATGCTGGCATAAGC
TTTCAGCGCCAAAGAAACGGTACGCTGGCGATCCACTGGTTTCCAGCCGAGTTTATCTTGTTCAGCGCGG
CGAGCTGCTAGCTCAGATTCGCTGACTTCGAGCGTGATCGAACGGTTGGGAATATCAATCGCGATGCTAT
CGCCACTGCGTACCAAGCCGATCGTACCGCCATTCGCCGCTTCCGGAGAGGCGTGACCAATCGACAAGCC
GGACGTACCACCGGAGAAGCGGCCATCGGTCAGTAGCGCGCACTGTTTACCCAGTCCCATCGATTTGAGG
TAGGTGGTTGGGTAGAGCATCTCTTGCATGCCCGGACCGCCTTTTGGCCCTTCATAACGAATAACCACGA
CGTCACCGGCTTTGACTTGGCCGCCAAGAATGCCGTTGACCGCGTCTTCCTGACTTTCATACACCACAGC
AGGACCACGGAATTTGAGGATACTTTCATCCACGCCAGCAGTTTTTACGATGCAGCCGTCAATCGCCAAG
TTGCCTTTGAGTACGGCAAGGCCACCATCTTGACTGAATGCGTGCGCTTTATCGCGAATACACCCCTCTT
GGCGATCGTCATCGAGCGTATCCCAACGGCAATCTTGTGAGAAAGCTTGAGTGGTGCGAATGCCAGCAGG
GCCTGCGCGGAACATAGTATGTACCGCTGGATCTTGGGTTTGTTTCACGTCGTATTGCGCCAGCTGCTCT
TGCAGCGAGATGCCTAGTACGGTGCGGGTTTGATCCTTGAGTAGACCTGCACGTTGTAGCTCACCCAAAA
TGCCCATTACACCGCCCGCGCGGTGTACATCTTCCATATGGTATTTCTGAGTGGAAGGCGCGACTTTACA
TAAGTGTGGCACTTGGCGAGACATGCGATCGATATCGGTCATATCAAATTCCACTTCGCCTTCCTGCGCA
GCGGCCAACAGGTGTAACACCGTGTTGGTGGAGCCGCCCATCGCAATATCCAGCGCAATGGCGTTTTCAA
ACGCTGCTTTGTTGGCAATGTTGCGTGGCAAAACTGAGGCATCATCTTGCTCGTAGTAACGTTTAGTCAG
CTCAACAATCCGTTGCCCAGCAGTCAAAAACAGCTGTTTGCGATCGGCATGCGTGGCGAGCAGTGAGCCG
TTACCCGGCTGAGAGAGACCCAGCGCTTCGGTCAAGCAGTTCATTGAGTTGGCGGTAAACATCCCCGAGC
AAGAGCCACAAGTAGGACAGGCCGAGCGTTCAATCTGCTCACTTTGGGCATCCGATACTTTGGGGTCAGC
GCCTTGCATCATGGCATCGACCAAGTCGAGCTTGATGATTTGGTCAGAAAGCTTGGTTTTTCCCGCTTCC
ATCGGGCCGCCAGAGACGAAAATCGCCGGAATATTAAGGCGCATCGCCGCCATCAGCATTCCTGGAGTGA
TTTTGTCACAGTTGGAGATACACACCATGGCATCGGCGCAGTGCGCATTGACCATGTATTCGACGGAATC
GGCGATCAGTTCACGCGATGGCAGCGAGTAGAGCATGCCGCCGTGGCCCATGGCGATGCCGTCATCGACC
GCAATGGTGTTGAATTCTTTGGCAATGCCGCCCGCGGCTTCAATTTCGCGTGCGACCAGTTGGCCGAGAT
CTTTTAAATGCACATGGCCGGGAACAAATTGGGTGAAGGAGTTGACCACCGCAATGATCGGTTTACCAAA
ATCTTCCTCTTTGACGCCGGTGGCGCGCCATAATGCGCGCGCACCCGCCATGTTACGTCCGTGTGTGGTG
GTGGCGGAACGGTACTTAGGCA
Protein Sequence 
>gi|227080265|ref|YP_002808816.1| dihydroxy-acid dehydratase [Vibrio cholerae M66-2] MPKYRSATTTHGRNMAGARALWRATGVKEEDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIEAAGGIAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRLNIPAIFVSGGPMEAGKTKLSDQIIKLDLVDAMMQGADPKVSDAQSEQIERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLTAGQRIVELTKRYYEQDDASVLPRNIANKAAFENAIALDIAMGGSTNTVLHLLAAAQEGEVEFDMTDIDRMSRQVPHLCKVAPSTQKYHMEDVHRAGGVMGILGELQRAGLLKDQTRTVLGISLQEQLAQYDVKQTQDPAVHTMFRAGPAGIRTTQAFSQDCRWDTLDDDRQEGCIRDKAHAFSQDGGLAVLKGNLAIDGCIVKTAGVDESILKFRGPAVVYESQEDAVNGILGGQVKAGDVVVIRYEGPKGGPGMQEMLYPTTYLKSMGLGKQCALLTDGRFSGGTSGLSIGHASPEAANGGTIGLVRSGDSIAIDIPNRSITLEVSESELAARRAEQDKLGWKPVDRQRTVSLALKAYASMATSADKGAVRDKSKLEG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ilvD mutant is attenuated in mice (Merrell et al., 2002).
COG COG0129EG, under E: Amino acid transport and metabolism; G: Carbohydrate transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].