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VC0835

Victor ID 2443
Gene Name VC0835
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2614502
NCBI Protein GI 15640852
Locus Tag VC0835
Genbank Accession AE003852
Protein Accession NP_230483
Other Database IDs UniProtKB-ID: TCPT_VIBCH
UniRef100: UniRef100_P29480
UniRef90: UniRef90_P29480
UniRef50: UniRef50_P29480
UniParc: UPI0000000A91
EMBL: X64098
EMBL: AE003852
EMBL-CDS: CAA45462.1
EMBL-CDS: AAF93998.1
RefSeq_NT: NC_002505.1
GenomeReviews: AE003852_GR
KEGG: vch:VC0835
TIGR: VC_0835
HOGENOM: HBG739733
OMA: MENDDES
ProtClustDB: CLSK793812
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 896154
Gene Ending Position 897665
Gene Strand (Orientation) +
Protein Name toxin co-regulated pilus biosynthesis protein T
Protein pI 7.23
Protein Weight 53902.39
Protein Length 503
Protein Note similar to SP:P29480 PID:48415; identified by sequence similarity; putative
DNA Sequence 
>gi|15640032:896154-897665 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
GATGTCAATTGATATAAAGTATTTAAGTCGTATTGATATAGATCGTGAGGAGTTTTTCTTTAAAGACTCG
AGATTAATGTGTAAGAAATTCGATGAAGAGCGTGAGGTATTAACTCTTCTCGAATTCGATACAAAATTTC
GGGTCAATCTTCTGAAGAAAGATAAAGTTTATAAGTATTTCTTAGTTTCAGATGCAAATCATAAATTATT
AATAGCGAATCTTGTTACCGAGCAGCAAGCTAAAGACTTAAGTTTTATAGAAAAAGATATAATGAAAATT
GCATCATCTGCTACAGCTTATGGTGCAAGTGACATCCACTTCATCCGAGAGGATAGGATTTGTAAAATAA
AATTCCGTGTGAATGGCACAATGATCGACTATAGAGAAATATTAAGTTCAGAAGCCGATGCGCTAATGTT
TGTTCTATACAATGTGATGGCAACAACGAAAGAAACGACGTGGAACCGAAAACTACCTCAAGATGCAAAT
ATTATTCTTGTGATCAACGAAAAGGCATATCGCTTTCGTTACGCACATATGCCTTTATTTGGTGAGGGAG
GGAAAAACTATCATGCGGTAGTTCGTATTATCTATCCTTCAAATAATTTTGTTTGTACAAACTATCAAGA
TATTGGGTATAACGAGGCTGATACCGATGCGATTGCAAGAATTCTAAATACATCTTATGGATTGTTCATT
GTTTCCGGAACAACAGGTTCTGGTAAATCAACATCTTTGAAAAAGTATATAGAATTACTTTTCTTTAATA
AATATAAGGGAAAAGGATGTTTTGTCACCGTTGAAGATCCTGTCGAGTATTTAATTTCTGGAGCACAGCA
AAGCTCAATTGTTGCCGATAATGATGATAAAACAAAGAACCCATTTGCTGATGCGGTACGTTCAGCGATG
CGTCGAGATCCGGACGTTATTATGATCGGTGAAATTCGTGATAAACCTACCGTTGAGGCTCTATCAAGTG
CTGTAGAAAGTGGCCACTATTGTCTTACGACCATCCATGCAGGTTCTGTTGTTTCTGTTTTACAAAGACT
TTCAGGATTAGGGATGAAGGCTGACAAAATAGCATCACCTGGATTTCTGGCTGGTATTACAAGTCAGAAA
TTAATTCCCGAACTTTGCCCAAGTTGTAAAGTTTCCTTTGTTGATGAACGTTATCAGCGTGCTGTATTTA
GCGCGAATGAAAATGGCTGTGAGGCATGTAATCATTCTGGGTTTAAAGGAAGGCTGCTTTTATTAGAAAC
ATTAGTCCCAACAGTTGAAGATTTAGAGCTAGTGGCGAGTGAAAACTGGGTTTCCCTTTATCGTAAATAT
CGGGAGCGACGCTTTATAAAAACTGGAAAAAAAGGTCTTGGTGAAGGCTTCAGCATTAAAGATAAAGCTT
ATTACAATGTTTTAAAAGGTAAAGTGTGTCACGAATATTTTATGCTGCATTTCGGTCAGTTAGATCATGA
GGATGAAAATATAATATATGAAAATTATCTCCAAGAAGTATA
Protein Sequence 
>gi|15640852|ref|NP_230483.1| toxin co-regulated pilus biosynthesis protein T [Vibrio cholerae O1 biovar El Tor str. N16961]
MSIDIKYLSRIDIDREEFFFKDSRLMCKKFDEEREVLTLLEFDTKFRVNLLKKDKVYKYFLVSDANHKLL
IANLVTEQQAKDLSFIEKDIMKIASSATAYGASDIHFIREDRICKIKFRVNGTMIDYREILSSEADALMF
VLYNVMATTKETTWNRKLPQDANIILVINEKAYRFRYAHMPLFGEGGKNYHAVVRIIYPSNNFVCTNYQD
IGYNEADTDAIARILNTSYGLFIVSGTTGSGKSTSLKKYIELLFFNKYKGKGCFVTVEDPVEYLISGAQQ
SSIVADNDDKTKNPFADAVRSAMRRDPDVIMIGEIRDKPTVEALSSAVESGHYCLTTIHAGSVVSVLQRL
SGLGMKADKIASPGFLAGITSQKLIPELCPSCKVSFVDERYQRAVFSANENGCEACNHSGFKGRLLLLET
LVPTVEDLELVASENWVSLYRKYRERRFIKTGKKGLGEGFSIKDKAYYNVLKGKVCHEYFMLHFGQLDHE
DENIIYENYLQEV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC0835 mutant is attenuated in mice (Merrell et al., 2002).
COG COG2804NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].