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VC0125

Victor ID 2466
Gene Name VC0125
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2615366
NCBI Protein GI 15640156
Locus Tag VC0125
Genbank Accession AE003852
Protein Accession NP_229783
Other Database IDs UniProtKB-ID: DCDA_VIBCH
UniRef100: UniRef100_Q9KVL7
UniRef90: UniRef90_Q9KVL7
UniRef50: UniRef50_Q9KVL7
UniParc: UPI0000128F78
EMBL: AE003852
EMBL-CDS: AAF93302.1
RefSeq_NT: NC_002505.1
PDB: 3N2B
GenomeReviews: AE003852_GR
KEGG: vch:VC0125
TIGR: VC_0125
HOGENOM: HBG672375
OMA: HLICFAV
ProtClustDB: CLSK873868
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 119228
Gene Ending Position 120481
Gene Strand (Orientation) +
Protein Name diaminopimelate decarboxylase
Protein pI 5.61
Protein Weight 43101.46
Protein Length 417
Protein Note similar to SP:P19572; identified by sequence similarity; putative
DNA Sequence 
>gi|15640032:119228-120481 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
TTTGGATTACTTCAATTATCAGGAAGATGGTCAGTTGTGGGCTGAGCAAGTTCCACTCGCCGATTTGGCA
AACCAGTACGGTACACCGCTTTATGTTTACTCAAGAGCGACACTTGAGCGCCATTGGCACGCGTTTGATA
AATCAGTCGGTGATTATCCTCACCTAATTTGTTATGCGGTGAAAGCCAACTCTAACTTAGGGGTATTGAA
TACTTTAGCTCGTTTGGGTTCAGGTTTTGATATCGTCTCCGTTGGCGAATTAGAGCGTGTATTGGCCGCC
GGTGGTGACCCAAGCAAGGTGGTATTCTCTGGTGTGGGTAAAACCGAAGCTGAGATGAAGCGCGCCCTGC
AATTGAAGATCAAATGCTTTAACGTGGAATCGGAGCCTGAGCTGCAGCGCCTGAATAAAGTGGCTGGCGA
GCTTGGTGTTAAAGCGCCGATTTCACTGCGCATCAATCCTGATGTGGATGCCAAAACTCACCCTTACATT
TCAACGGGTCTACGTGATAACAAATTTGGTATCACCTTTGACCGCGCAGCGCAGGTATATCGCTTAGCGC
ACAGCTTACCCAACCTCGATGTACATGGTATTGACTGCCATATCGGCTCACAGCTAACCGCTCTCGCACC
GTTTATTGATGCGACTGACCGTTTACTGGCACTGATTGATTCGCTGAAAGCGGAAGGCATTCATATCCGC
CACTTGGATGTCGGCGGTGGTTTAGGGGTGGTTTATCGTGATGAACTGCCTCCGCAGCCTTCGGAATACG
CCAAAGCATTGCTGGACCGCCTAGAGCGCCACCGCGATTTAGAGCTGATTTTTGAACCGGGACGCGCGAT
TGCGGCTAACGCGGGAGTATTGGTGACTAAGGTGGAGTTTCTCAAACACACTGAGCACAAAAACTTCGCG
ATCATTGATGCGGCGATGAACGATTTGATCCGCCCGGCGCTATACCAAGCGTGGCAAGACATCATTCCAC
TGCGTCCGCGCCAAGGCGAAGCCCAAACTTATGATTTGGTTGGCCCGGTGTGTGAAACCAGTGATTTCCT
AGGGAAAGATCGCGACTTAGTGTTGCAAGAGGGGGATTTACTGGCGGTGCGCTCTTCTGGTGCGTATGGG
TTTACCATGTCGTCGAATTACAATACCCGTCCGCGAGTGGCTGAAGTCATGGTTGATGGCAATAAAACCT
ATTTGGTGCGTCAGCGTGAAGAGCTTAGCAGCTTGTGGGCGTTAGAATCGGTATTACCGGAGTA
Protein Sequence 
>gi|15640156|ref|NP_229783.1| diaminopimelate decarboxylase [Vibrio cholerae O1 biovar El Tor str. N16961]
MDYFNYQEDGQLWAEQVPLADLANQYGTPLYVYSRATLERHWHAFDKSVGDYPHLICYAVKANSNLGVLN
TLARLGSGFDIVSVGELERVLAAGGDPSKVVFSGVGKTEAEMKRALQLKIKCFNVESEPELQRLNKVAGE
LGVKAPISLRINPDVDAKTHPYISTGLRDNKFGITFDRAAQVYRLAHSLPNLDVHGIDCHIGSQLTALAP
FIDATDRLLALIDSLKAEGIHIRHLDVGGGLGVVYRDELPPQPSEYAKALLDRLERHRDLELIFEPGRAI
AANAGVLVTKVEFLKHTEHKNFAIIDAAMNDLIRPALYQAWQDIIPLRPRQGEAQTYDLVGPVCETSDFL
GKDRDLVLQEGDLLAVRSSGAYGFTMSSNYNTRPRVAEVMVDGNKTYLVRQREELSSLWALESVLPE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC0125 mutant is attenuated in mice (Merrell et al., 2002).
COG COG0019E, under E: Amino acid transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].