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cyaA from Vibrio cholerae O1 biovar El Tor str. N16961

Victor ID 2394
Gene Name cyaA from Vibrio cholerae O1 biovar El Tor str. N16961
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2612962
NCBI Protein GI 15640154
Locus Tag VC0122
Protein Accession NP_229781.1
Other Database IDs UniProtKB-ID: Q9KVL9_VIBCH
UniRef100: UniRef100_A5F4J0
UniRef90: UniRef90_A5F4J0
UniRef50: UniRef50_Q59685
UniParc: UPI00000C2BE0
EMBL: AE003852
EMBL-CDS: AAF93300.1
RefSeq_NT: NC_002505.1
GenomeReviews: AE003852_GR
KEGG: vch:VC0122
TIGR: VC_0122
HOGENOM: HBG678054
OMA: LWQLYKG
ProtClustDB: PRK09450
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 116052
Gene Ending Position 118583
Gene Strand (Orientation) +
Protein Name adenylate cyclase
DNA Sequence 
>gi|15640032:116052-118583 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
CTTGCAGGCTTATACTCAGACCTTAATCCATAGACTTGATAAGCTAAACCGGCAACGTATTGAGCGTGCG
CTGGCTCTTATGGATTTGCAAAGTCAACGTGTTTTCCACCTCATTCCCGCACTATTTCAATTTAATCATC
CTCTGATCCCCGGTTATTTTTCTGCTGATACGCCTTTCGGTATCCATCTGTTTGAAGCCAATCCTATCCA
GCAGCAATTCATCGATGATGCTCAGTTGACGCTCGGCGAGCCGTTAACGCCAGCTGACAATCCGGCGATT
TTAGGCTTGTATACGATGGGCAGTACCTCATCGATCGGTCAAAGCACATCGAGCGATCTGGATATTTGGG
TCTGTGTCTCTGCTCAAATGAGTTGTGAGGCGCGCGACAACCTCTCCAGTAAATGTCTGCTCATTACCGA
TTGGGCGAAAAGTCAGGGTGTTGAAGCCAATTTCTTCATCATGAATGAAGAGCGTTTTCGCCATAACCAT
TCCGAAGCGTTAAGCGGTGAAAACTGTGGTTCATCACAGCACTTATTATTATTGGATGAGTTTTATCGCT
CTGCGGTGCGCTTAGCGGGCAAGCGACTGCTGTGGCAAATCGTGCCACCAGAAATGGAAGAGTGCTACGA
CGAATATGTTCACGAGCTCTGTTCAAATGGGTATTTGAACTGCAATGAATGGATCGATTTTGGCAAGTTA
AACCGCATTCCGGCTGAAGAGTACTTTGGCGCGAACTTGTGGCAACTGTATAAGAGCATTGACTCGCCTT
ATAAATCGGTACTGAAAGCCATTTTGCTTGAAGCCTATTCGTGGGAGTACCCGCACACTCAACTGTTGAG
TATCGACAGCAAACGCCGTTTCTTTGCCGATGAACCGGATCTGTACGGCATGGACTCTTACTATCAGATG
TTAGAGAAAGTGACGCGCTATTTGGTGCGAATTGGTGATAGCACGCGCCTTGATTTAGTGCGCCGCTGTT
TCTATCTCAAAACCCATGAGAAGTTGTCGCGTGAGCCGGGCGTCGGCTCGATGCCTTGGCGTCGTGAAGC
GTTACGGGAACTGACCAGCGAATGGCAATGGAGCGCAGATTTGATTGCCGAGCTCGATAACCGTCGTCAC
TGGAAAGTCGAGCAAGTGAAGGTCGTGCACCACGCACTGCTTGATGCCTTGATGCTCAGCTATCGTAACC
TGATCCAGTTTGCGCGTCGTAATGACATCACCTCGGCCATTAGCCCACAAGATATCTCGATTTTGGCGCG
TAAACTGTACGCGGCGTTTGAAGTGCTGCCGGGGAAAGTCACACTGCTCAACCCACAAATTTCCCCAGAC
CTGCATGAGCCCGATTTAAGTTTTATTGAGGTTTGTGCTGGACGCACCAATAAGCCCGGTTGGTATCTCT
ACAAGCAGCCGCTGCAGGCGCAGCGCTTGATTGGTCAGCCGTATCTTGAGCACAACGAATACTTGAGTAA
ATTGGTGGCTTGGGCCTTTTTTAATGGCCTGATCACTGAGTCGACTCGTTTGCATGCGGTGGTGCGTGAA
GCGCAGCTGGACATCGACAAGTTCTACCAAATGGTCAGCGATCTGCGTAATACCTTTTCGCTGCGTAAGC
GTCGCCCTACTATGCAAGCGCTGGCCAATCCTTGTGAGATTAGCCAGCTTGCCATGTTCATCAATTTTGA
ACACGACCCAACCAGTGAATTGAGTGGGAAAGCGCTGAAAGTCGACCTGAAAAATATCGATATTTTTAGT
TTTGGTGCTGAGCAGAAATGCTTAGTCGGCAGTGTCGATTTGGTGTATCGCAACTCGTGGCAAGAAGTGC
GTACCCTGCATTTTGAAGGCCAGACGGCCATGCTTGATGCGTTGAAAACCGTGCTTGGAAAAATGCATCA
GGATGCGCTGCCGCCAGAATCGGTGGATGTGTTCTGCTACAGCAAAAACTTGCGCGGCGTGATGCGTAAC
TTGGTTTATCAACTGTTGGCTGAGTGTATCGATTTGCGCCTCAAGCCGATGGAGCAAGAGAAACGTCGTC
GTTTCAAAGCGCTGCGCATGGGCGATCAGATGTATGGTTTGTTCTTTGAACGTCGTGGTGTTTCGGTTCA
GAAGTTGGAGAACTCGGTTGATTTCTATCGCAGCATCTCAACCAATAAGCTCAAGGGCTCGCCTTTACTG
ATGCTCGATCGCGATCAAGATTACCCATTGCCAGCGGTGGTGGATAGTTTTGCCAGTGAAGGTTTGGTGC
AGTTCTTCTTTGAAGATACCGAGAAAGGTTTCAACATCTATGTGCTTGATGAGGCCAACCGCGTTGAAGT
CTATCACCAGTTTAATGGCGAAAAAGACGAAATGATTGCCAGCGTCAACAGCTTCTACACCTCGATGTTG
GATGACAGCAATAAACTCGGCGCGAAAAGCATCAATTTTAACTTGCCGCAGTATTACCAAATCATCCACC
CTGAAGAGGGAGAAACGTACGTGGTGCCGTACCGTAACGACAGCGCTGTGTATTCCAAGCCTTCGCAAGT
GGTCAATGCCTA
Protein Sequence 
>gi|15640154|ref|NP_229781.1| adenylate cyclase [Vibrio cholerae O1 biovar El Tor str. N16961] MQAYTQTLIHRLDKLNRQRIERALALMDLQSQRVFHLIPALFQFNHPLIPGYFSADTPFGIHLFEANPIQQQFIDDAQLTLGEPLTPADNPAILGLYTMGSTSSIGQSTSSDLDIWVCVSAQMSCEARDNLSSKCLLITDWAKSQGVEANFFIMNEERFRHNHSEALSGENCGSSQHLLLLDEFYRSAVRLAGKRLLWQIVPPEMEECYDEYVHELCSNGYLNCNEWIDFGKLNRIPAEEYFGANLWQLYKSIDSPYKSVLKAILLEAYSWEYPHTQLLSIDSKRRFFADEPDLYGMDSYYQMLEKVTRYLVRIGDSTRLDLVRRCFYLKTHEKLSREPGVGSMPWRREALRELTSEWQWSADLIAELDNRRHWKVEQVKVVHHALLDALMLSYRNLIQFARRNDITSAISPQDISILARKLYAAFEVLPGKVTLLNPQISPDLHEPDLSFIEVCAGRTNKPGWYLYKQPLQAQRLIGQPYLEHNEYLSKLVAWAFFNGLITESTRLHAVVREAQLDIDKFYQMVSDLRNTFSLRKRRPTMQALANPCEISQLAMFINFEHDPTSELSGKALKVDLKNIDIFSFGAEQKCLVGSVDLVYRNSWQEVRTLHFEGQTAMLDALKTVLGKMHQDALPPESVDVFCYSKNLRGVMRNLVYQLLAECIDLRLKPMEQEKRRRFKALRMGDQMYGLFFERRGVSVQKLENSVDFYRSISTNKLKGSPLLMLDRDQDYPLPAVVDSFASEGLVQFFFEDTEKGFNIYVLDEANRVEVYHQFNGEKDEMIASVNSFYTSMLDDSNKLGAKSINFNLPQYYQIIHPEEGETYVVPYRNDSAVYSKPSQVVNA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cyaA mutant is attenuated in mice (Merrell et al., 2002).
COG COG3072F, under F: Nucleotide transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].