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purK from Vibrio cholerae O395

Victor ID 2368
Gene Name purK from Vibrio cholerae O395
Sequence Strain (Species/Organism) Vibrio cholerae O395
NCBI Gene ID 5137360
NCBI Protein GI 147674298
Locus Tag VC0395_A2468
Protein Accession YP_001218361.1
Taxonomy ID 345073
Chromosome No 2
Gene Starting Position 2619870
Gene Ending Position 2621003
Gene Strand (Orientation) +
Protein Name phosphoribosylaminoimidazole carboxylase ATPase subunit
DNA Sequence 
>gi|147673035:2619870-2621003 Vibrio cholerae O395 chromosome 2, complete sequence
GATGCGTGTGTTGGTTCTCGGCGCTGGTCAGCTGGCGCGCATGATGTCGCTCGCCGGAGCACCGCTCAAT
ATTGAAACGATCGCTTTTGATGTGGGTAGCGAAAACATTGTGCACCCCTTAACGCAAACTGTGCTTGGGC
ATGGATTGGAGCAAGCGATTGAACAAGTCGATGTGATCACCGCTGAGTTTGAACACATTCCGCATCCGAT
CCTCGATCTCTGTGCACGCAGTGGCAAACTTTACCCAAGCGCTGAAGCTATCAAAGCTGGCGGCGATCGT
CGTTTAGAAAAAGCCTTGCTGGATCGCGCCCAAGTGGCGAATGCACGTTATACGATGATCCGCAGCCGAG
ACGACCTAACCTCAGCCATCGCCGAGATTGGATTGCCTATGGTGCTGAAAAGTGCACTCGGAGGCTACGA
TGGAAAAGGCCAATGGCGCTTGAAAGAACCAACGCAGATCGAATCGGTTTGGCAAGAACTTGCGCAATAT
CTGGCAGCCAACCCCGAACAAGCAATTGTGGCAGAAGAATTTGTCGCTTTTGATCGCGAAGTGTCACTGG
TCGGTGCACGTAACCTAGTCGGCGATGTTGTGGTGTATCCTTTAGCGGAGAACGTTCATACCCAAGGTGT
GTTGAGCCTTTCTACCGCCATTGATGCTCCTGCGCTACAAACTCAAGCGAAAGCCATGTTTAAAGCGGTA
GCCGAGCAGCTCAATTATGTCGGTGTATTAGCGCTGGAGTTTTTTGAAGTACAAGGCCAGTTACTGGTCA
ATGAAATTGCACCACGAGTTCATAACTCCGGTCACTGGACTCAGCAAGGTGCGGAAACCTGTCAGTTCGA
AAACCACTTACGCGCAGTGTGTGGCTTACCGCTGGGTAGCACCAAACTGGTTCGTGAGACCGCGATGATT
AATATTCTTGGTGAAGATCAGCTGCCCGCAGAAGTATTGGCACTGGAAGGCTGCCACGTACATTGGTACG
GCAAGGCCAAGCGCTCAGGACGCAAGATGGGGCATATCAATGTGACCGCCGATTACAGTGGTGAGTTGCA
ACGCAAATTATGCCAATTAGCGACTGTGTTAGATGAAAAGGCTTTTCCTGCCGTACACGCCGTAGCAAAG
GAAATTCAGCCTTA
Protein Sequence 
>gi|147674298|ref|YP_001218361.1| phosphoribosylaminoimidazole carboxylase ATPase subunit [Vibrio cholerae O395] MRVLVLGAGQLARMMSLAGAPLNIETIAFDVGSENIVHPLTQTVLGHGLEQAIEQVDVITAEFEHIPHPILDLCARSGKLYPSAEAIKAGGDRRLEKALLDRAQVANARYTMIRSRDDLTSAIAEIGLPMVLKSALGGYDGKGQWRLKEPTQIESVWQELAQYLAANPEQAIVAEEFVAFDREVSLVGARNLVGDVVVYPLAENVHTQGVLSLSTAIDAPALQTQAKAMFKAVAEQLNYVGVLALEFFEVQGQLLVNEIAPRVHNSGHWTQQGAETCQFENHLRAVCGLPLGSTKLVRETAMINILGEDQLPAEVLALEGCHVHWYGKAKRSGRKMGHINVTADYSGELQRKLCQLATVLDEKAFPAVHAVAKEIQP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: purK mutant is attenuated in mice (Chiang and Mekalanos, 1998).
COG COG0026F, under F: Nucleotide transport and metabolism
References
Chiang and Mekalanos, 1998: Chiang SL, Mekalanos JJ. Use of signature-tagged transposon mutagenesis to identify Vibrio cholerae genes critical for colonization. Molecular microbiology. 1998; 27(4); 797-805. [PubMed: 9515705].