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cyaA from Vibrio cholerae M66-2

Victor ID 3844
Gene Name cyaA from Vibrio cholerae M66-2
Sequence Strain (Species/Organism) Vibrio cholerae M66-2
NCBI Gene ID 7771419
NCBI Protein GI 227080358
Locus Tag VCM66_0122
Protein Accession YP_002808909.1
Other Database IDs UniProtKB-ID: C3LPW4_VIBCM
UniRef100: UniRef100_A5F4J0
UniRef90: UniRef90_A5F4J0
UniRef50: UniRef50_Q59685
UniParc: UPI00000C2BE0
EMBL: CP001233
EMBL-CDS: ACP04458.1
RefSeq_NT: NC_012578.1
GenomeReviews: CP001233_GR
KEGG: vcm:VCM66_0122
OMA: LWQLYKG
ProtClustDB: PRK09450
Taxonomy ID 579112
Chromosome No I
Gene Starting Position 116017
Gene Ending Position 118548
Gene Strand (Orientation) +
Protein Name adenylate cyclase
DNA Sequence 
>gi|227080237:116017-118548 Vibrio cholerae M66-2 chromosome I, complete genome
CTTGCAGGCTTATACTCAGACCTTAATCCATAGACTTGATAAGCTAAACCGGCAACGTATTGAGCGTGCG
CTGGCTCTTATGGATTTGCAAAGTCAACGTGTTTTCCACCTCATTCCCGCACTATTTCAATTTAATCATC
CTCTGATCCCCGGTTATTTTTCTGCTGATACGCCTTTCGGTATCCATCTGTTTGAAGCCAATCCTATCCA
GCAGCAATTCATCGATGATGCTCAGTTGACGCTCGGCGAGCCGTTAACGCCAGCTGACAATCCGGCGATT
TTAGGCTTGTATACGATGGGCAGTACCTCATCGATCGGTCAAAGCACATCGAGCGATCTGGATATTTGGG
TCTGTGTCTCTGCTCAAATGAGTTGTGAGGCGCGCGACAACCTCTCCAGTAAATGTCTGCTCATTACCGA
TTGGGCGAAAAGTCAGGGTGTTGAAGCCAATTTCTTCATCATGAATGAAGAGCGTTTTCGCCATAACCAT
TCCGAAGCGTTAAGCGGTGAAAACTGTGGTTCATCACAGCACTTATTATTATTGGATGAGTTTTATCGCT
CTGCGGTGCGCTTAGCGGGCAAGCGACTGCTGTGGCAAATCGTGCCACCAGAAATGGAAGAGTGCTACGA
CGAATATGTTCACGAGCTCTGTTCAAATGGGTATTTGAACTGCAATGAATGGATCGATTTTGGCAAGTTA
AACCGCATTCCGGCTGAAGAGTACTTTGGCGCGAACTTGTGGCAACTGTATAAGAGCATTGACTCGCCTT
ATAAATCGGTACTGAAAGCCATTTTGCTTGAAGCCTATTCGTGGGAGTACCCGCACACTCAACTGTTGAG
TATCGACAGCAAACGCCGTTTCTTTGCCGATGAACCGGATCTGTACGGCATGGACTCTTACTATCAGATG
TTAGAGAAAGTGACGCGCTATTTGGTGCGAATTGGTGATAGCACGCGCCTTGATTTAGTGCGCCGCTGTT
TCTATCTCAAAACCCATGAGAAGTTGTCGCGTGAGCCGGGCGTCGGCTCGATGCCTTGGCGTCGTGAAGC
GTTACGGGAACTGACCAGCGAATGGCAATGGAGCGCAGATTTGATTGCCGAGCTCGATAACCGTCGTCAC
TGGAAAGTCGAGCAAGTGAAGGTCGTGCACCACGCACTGCTTGATGCCTTGATGCTCAGCTATCGTAACC
TGATCCAGTTTGCGCGTCGTAATGACATCACCTCGGCCATTAGCCCACAAGATATCTCGATTTTGGCGCG
TAAACTGTACGCGGCGTTTGAAGTGCTGCCGGGGAAAGTCACACTGCTCAACCCACAAATTTCCCCAGAC
CTGCATGAGCCCGATTTAAGTTTTATTGAGGTTTGTGCTGGACGCACCAATAAGCCCGGTTGGTATCTCT
ACAAGCAGCCGCTGCAGGCGCAGCGCTTGATTGGTCAGCCGTATCTTGAGCACAACGAATACTTGAGTAA
ATTGGTGGCTTGGGCCTTTTTTAATGGCCTGATCACTGAGTCGACTCGTTTGCATGCGGTGGTGCGTGAA
GCGCAGCTGGACATCGACAAGTTCTACCAAATGGTCAGCGATCTGCGTAATACCTTTTCGCTGCGTAAGC
GTCGCCCTACTATGCAAGCGCTGGCCAATCCTTGTGAGATTAGCCAGCTTGCCATGTTCATCAATTTTGA
ACACGACCCAACCAGTGAATTGAGTGGGAAAGCGCTGAAAGTCGACCTGAAAAATATCGATATTTTTAGT
TTTGGTGCTGAGCAGAAATGCTTAGTCGGCAGTGTCGATTTGGTGTATCGCAACTCGTGGCAAGAAGTGC
GTACCCTGCATTTTGAAGGCCAGACGGCCATGCTTGATGCGTTGAAAACCGTGCTTGGAAAAATGCATCA
GGATGCGCTGCCGCCAGAATCGGTGGATGTGTTCTGCTACAGCAAAAACTTGCGCGGCGTGATGCGTAAC
TTGGTTTATCAACTGTTGGCTGAGTGTATCGATTTGCGCCTCAAGCCGATGGAGCAAGAGAAACGTCGTC
GTTTCAAAGCGCTGCGCATGGGCGATCAGATGTATGGTTTGTTCTTTGAACGTCGTGGTGTTTCGGTTCA
GAAGTTGGAGAACTCGGTTGATTTCTATCGCAGCATCTCAACCAATAAGCTCAAGGGCTCGCCTTTACTG
ATGCTCGATCGCGATCAAGATTACCCATTGCCAGCGGTGGTGGATAGTTTTGCCAGTGAAGGTTTGGTGC
AGTTCTTCTTTGAAGATACCGAGAAAGGTTTCAACATCTATGTGCTTGATGAGGCCAACCGCGTTGAAGT
CTATCACCAGTTTAATGGCGAAAAAGACGAAATGATTGCCAGCGTCAACAGCTTCTACACCTCGATGTTG
GATGACAGCAATAAACTCGGCGCGAAAAGCATCAATTTTAACTTGCCGCAGTATTACCAAATCATCCACC
CTGAAGAGGGAGAAACGTACGTGGTGCCGTACCGTAACGACAGCGCTGTGTATTCCAAGCCTTCGCAAGT
GGTCAATGCCTA
Protein Sequence 
>gi|227080358|ref|YP_002808909.1| adenylate cyclase [Vibrio cholerae M66-2] MQAYTQTLIHRLDKLNRQRIERALALMDLQSQRVFHLIPALFQFNHPLIPGYFSADTPFGIHLFEANPIQQQFIDDAQLTLGEPLTPADNPAILGLYTMGSTSSIGQSTSSDLDIWVCVSAQMSCEARDNLSSKCLLITDWAKSQGVEANFFIMNEERFRHNHSEALSGENCGSSQHLLLLDEFYRSAVRLAGKRLLWQIVPPEMEECYDEYVHELCSNGYLNCNEWIDFGKLNRIPAEEYFGANLWQLYKSIDSPYKSVLKAILLEAYSWEYPHTQLLSIDSKRRFFADEPDLYGMDSYYQMLEKVTRYLVRIGDSTRLDLVRRCFYLKTHEKLSREPGVGSMPWRREALRELTSEWQWSADLIAELDNRRHWKVEQVKVVHHALLDALMLSYRNLIQFARRNDITSAISPQDISILARKLYAAFEVLPGKVTLLNPQISPDLHEPDLSFIEVCAGRTNKPGWYLYKQPLQAQRLIGQPYLEHNEYLSKLVAWAFFNGLITESTRLHAVVREAQLDIDKFYQMVSDLRNTFSLRKRRPTMQALANPCEISQLAMFINFEHDPTSELSGKALKVDLKNIDIFSFGAEQKCLVGSVDLVYRNSWQEVRTLHFEGQTAMLDALKTVLGKMHQDALPPESVDVFCYSKNLRGVMRNLVYQLLAECIDLRLKPMEQEKRRRFKALRMGDQMYGLFFERRGVSVQKLENSVDFYRSISTNKLKGSPLLMLDRDQDYPLPAVVDSFASEGLVQFFFEDTEKGFNIYVLDEANRVEVYHQFNGEKDEMIASVNSFYTSMLDDSNKLGAKSINFNLPQYYQIIHPEEGETYVVPYRNDSAVYSKPSQVVNA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: cyaA mutant is attenuated in mice (Merrell et al., 2002).
COG COG3072F, under F: Nucleotide transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].