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VC0250

Victor ID 2433
Gene Name VC0250
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2614278
NCBI Protein GI 15640280
Locus Tag VC0250
Genbank Accession AE003852
Protein Accession NP_229907
Other Database IDs UniProtKB-ID: Q9KVA0_VIBCH
UniRef100: UniRef100_A5F3X1
UniRef90: UniRef90_A5F3X1
UniRef50: UniRef50_A5F3X1
UniParc: UPI00000C2C42
EMBL: AE003852
EMBL-CDS: AAF93426.1
RefSeq_NT: NC_002505.1
GenomeReviews: AE003852_GR
KEGG: vch:VC0250
TIGR: VC_0250
HOGENOM: HBG264484
OMA: PAEANDI
ProtClustDB: CLSK793543
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 256176
Gene Ending Position 257300
Gene Strand (Orientation) +
Protein Name iron-containing alcohol dehydrogenase family protein RfbM
Protein pI 5.62
Protein Weight 38351.75
Protein Length 374
Protein Note similar to GB:M26941 SP:P13604 PID:144714; identified by sequence similarity; putative
DNA Sequence 
>gi|15640032:256176-257300 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
CATGCTAAAACTACGTTTCCCACTACCTGTATTCCGTAACGCCCGAGAAATCGCTAATGGCAGGAATGCC
CGAATGGCGTTAAAAGGTTTAGTAGCTAACCGAGCTGCACTTATTATTAGCCCTTCCTTTGGGAGTTCTC
AGTACTTTGAACAAGTCGTTCGCCTTATTAACGCACAAAGTGTCCGGGTGATAGAGCGCTCTTGGCAAGG
AGAACCAAGTGTAGAGGAACTTTCTGGAGTTATTGGAGAGCTTGAAGATTTTAAGCCAGACTATATTCTT
GCACTTGGCGGCGGTTCTATCATTGATGGAGCTAAGCTCGCTTGGTTATTCTACGAATGCCCAACTCTTG
AATCAGAACTTCTATATCGACCATTTGCATTGCCATCCCTTCGTGGTCGCGCAAAATTTGCTGCAATACC
AACAACGGTAGGGGCTGGCTCTGAAGTTTCATCCGCTGCTGTCATGCTTGATAGTGTTACAAACAGCAAA
AAGGCAGTTGTCACTCATGATTTTTTACCAGACTTAGTGATCCTTGATCCTGACTTGGTTTCAGAAGTTC
CACCTAAGGTATTGAAAACAACTGTGGCCGATGCTCTCTCTCACGCCATTGAAGGTTATGTCTCTTTGAT
TGATAACCCTTTGATGAATACTTTTGCTGAGCAGGCGGTATCAATAATCTACCGCTATCGACATCAATTT
TCCAATGATAATTGGAGCAGCGAAATGCTTTCTGAACTGCAACAAGCTGCTATGTTTGCAGGGTGGGTTC
AAAATCATTGCATAGTTGGTCTTTCACATGCCATTGCTCACCAGCTAGGTACGTTTAATATAGGCCACGG
ATTGGCGAACGGTTTATTAATGCCTGCGGTGATCAACTTTAATTACCGCGAACATACAGCTGCAACTAAG
TATGAACAATTGATCTATAAATCCGGGTTACCTAATAAAGAAGCATTATTAGAACTTTTTGAAGTATTGG
TAGGAGAACAGAAAACTGATATGCATTTTTCAGAACAACAGCTGACAACGATCGCTGAAAATGCTTTACT
TGACCCTGCTGCTAAGTCAAATCCTGTTCGATTTACAGAAAACGATGTGAAAGAGATTGTGAAGCAATGC
CTGTA
Protein Sequence 
>gi|15640280|ref|NP_229907.1| iron-containing alcohol dehydrogenase family protein RfbM [Vibrio cholerae O1 biovar El Tor str. N16961]
MLKLRFPLPVFRNAREIANGRNARMALKGLVANRAALIISPSFGSSQYFEQVVRLINAQSVRVIERSWQG
EPSVEELSGVIGELEDFKPDYILALGGGSIIDGAKLAWLFYECPTLESELLYRPFALPSLRGRAKFAAIP
TTVGAGSEVSSAAVMLDSVTNSKKAVVTHDFLPDLVILDPDLVSEVPPKVLKTTVADALSHAIEGYVSLI
DNPLMNTFAEQAVSIIYRYRHQFSNDNWSSEMLSELQQAAMFAGWVQNHCIVGLSHAIAHQLGTFNIGHG
LANGLLMPAVINFNYREHTAATKYEQLIYKSGLPNKEALLELFEVLVGEQKTDMHFSEQQLTTIAENALL
DPAAKSNPVRFTENDVKEIVKQCL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC0250 mutant is attenuated in mice (Merrell et al., 2002).
COG COG1454C, under C: Energy production and conversion
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].