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VC1595

Victor ID 2426
Gene Name VC1595
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2613849
NCBI Protein GI 15641603
Locus Tag VC1595
Genbank Accession AE003852
Protein Accession NP_231235
Other Database IDs UniProtKB-ID: GAL1_VIBCH
UniRef100: UniRef100_Q9KRP1
UniRef90: UniRef90_Q9KRP1
UniRef50: UniRef50_C4LB24
UniParc: UPI000012B06B
EMBL: AE003852
EMBL-CDS: AAF94749.1
RefSeq_NT: NC_002505.1
GenomeReviews: AE003852_GR
KEGG: vch:VC1595
TIGR: VC_1595
HOGENOM: HBG725121
OMA: YNDGFVM
ProtClustDB: PRK05101
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 1706984
Gene Ending Position 1708201
Gene Strand (Orientation) -
Protein Name galactokinase
Protein pI 5.15
Protein Weight 39947.93
Protein Length 405
Protein Note catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism
DNA Sequence 
>gi|15640032:1706984-1708201 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
CTTATGCAAGCTCAACCAATCCCGCGCCCGAAGTTGCATGGCAGACATAGATCGATGCCTTCAGCCCTGT
CGCAGCTTCATAGTGTTCAGCCACCGCTTGCTGCACCGCTTCTACTTGCTTCGGGTGTACAAGGGCCACC
ACACAACCACCAAAGCCGCCGCCAGTCATCCGCACACCGCCTTGATCGCCAATCACAGATTGAACAATCT
CGACCAGCGTATCTATCTCCTTGACAGTGATTTCAAAATCATCACGCATCGAAGCGTGAGAAGCGGCCAT
TAACTCGCCTAAGCGCGGCATGTTTCCTTCACGCAGGGCCTGAGCGGCATGTAAAGTGCGTTCATTTTCC
GTGATGACATGGCGCGCACGTTTGGCCACCACAGGATCAAGTTCGGCCTGCTTTGCAGTCAATTGCGCCA
AAGTGACATCGCGTAGCGCTTTCACACCAAAAGTTTTGGCTGCGGCTTCGCATTGCTGACGACGGGTATT
GTATTCACTCTCCACCAAGCCGCGTTTTTTATTGGAATTGAGGATCACCACTGCCATCTGCTCTGGCATC
GCAACGGCCTCGGTTTGCAAGCTACGACAATCAAGCAACATGGCATGGTTCGCTTGCCCCTGCGCCGAGA
TCATCTGATCCATAATGCCGCAGTTACAACCGACAAACTGGTTCTCCGCTTGCTGGCCATTGAGGGCGAT
CTCCGCCTGACTGATTTTTAGCTGGTAAAGCTCTTTAAAAGTTTGCCCAATCACGACTTCTAAAGCCGCC
GAGGAACTGAGACCCGCCCCTTGAGGTACGTTACCTGAGACCACAATATCTGCCCCATTAAACTCAAAAC
CACGTTCAATCAAGCACTTGATTACACCGCGAATATAGTTCGACCACATTTTTTTAGGCTGAAAGGCAAT
CTCTTCTCGCAGGTCAAATTCGTCCGTGTCATTGTCGTAATCGACGGCGACCAAACGCACTAGAAAGTCT
TCCCGTTTGGCTGCAGCCACGACGGTTTGGTAGTTAATCGCGCAAGGCAGCACAAAGCCATCGTTGTAGT
CGGTGTGCTCGCCGATCAAATTGACCCGCCCCGGAGCTTGCACAAGGTGCGTAGCATCATAGCCAAAGAG
TTGTGCAAAGGTTGTAGTCACGTTTTGGATTAATTCAGACATAGGGCTTCTCACTTTAAATGGGGAGAGC
GACGCTGGCGTTGGTGCTGCGCCGCTCA
Protein Sequence 
>gi|15641603|ref|NP_231235.1| galactokinase [Vibrio cholerae O1 biovar El Tor str. N16961]
MSGAAPTPASLSPFKVRSPMSELIQNVTTTFAQLFGYDATHLVQAPGRVNLIGEHTDYNDGFVLPCAINY
QTVVAAAKREDFLVRLVAVDYDNDTDEFDLREEIAFQPKKMWSNYIRGVIKCLIERGFEFNGADIVVSGN
VPQGAGLSSSAALEVVIGQTFKELYQLKISQAEIALNGQQAENQFVGCNCGIMDQMISAQGQANHAMLLD
CRSLQTEAVAMPEQMAVVILNSNKKRGLVESEYNTRRQQCEAAAKTFGVKALRDVTLAQLTAKQAELDPV
VAKRARHVITENERTLHAAQALREGNMPRLGELMAASHASMRDDFEITVKEIDTLVEIVQSVIGDQGGVR
MTGGGFGGCVVALVHPKQVEAVQQAVAEHYEAATGLKASIYVCHATSGAGLVELA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC1595 mutant is attenuated in mice (Merrell et al., 2002).
COG COG0153G, under G: Carbohydrate transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].