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pykF from Vibrio cholerae O395

Victor ID 2329
Gene Name pykF from Vibrio cholerae O395
Sequence Strain (Species/Organism) Vibrio cholerae O395
NCBI Gene ID 5135110
NCBI Protein GI 147674848
Locus Tag VC0395_A0037
Protein Accession YP_001216011.1
Taxonomy ID 345073
Chromosome No 2
Gene Starting Position 32850
Gene Ending Position 34262
Gene Strand (Orientation) -
Protein Name pyruvate kinase
DNA Sequence 
>gi|147673035:32850-34262 Vibrio cholerae O395 chromosome 2, complete sequence
ATTACAGTACGTGTACTGATGCAGTGTTCGTTGTGCCAGAAGCAACCAGTGCGCCTGAAACCATCACTAC
GATGTCGCCTTTCTTGCCAAGGCCAGATTGCAGCGCAATCTCTTTACCTAGGTGGTAGAAAGCGTCAGTG
TTGTCAATCGCGTCAACCACAACTGGCGTTACACCTTTAGAAAGCACTAACTGAGCTGCTGTTTTCTTGT
TGGTGGTGACTGCAATAATGTTAGCCGTTGGGAAGTACTTACGAACTGAACGAGCAGATTTACCCGCTTC
AGTTGCTACGATGATCAGTGGCGCTGCCAGTTTCTCTGCGGTGTCTACTGCACCTTTACATACGGCTTCA
GTGATACGTAGACGTGGGCTGTCTAGGCGTGAACCCAGTTCTGCTTTCAGTACAGGGTCAGTACGCTCAG
CAATTTGCGCCATGATCTTCACCGCTTCAACTGGGTACTTACCTTTTGCTGTTTCGCCAGAAAGCATTAC
AGCATCAGTACCATCCATGATCGCGTTCGCAACGTCGCCCGCTTCTGCGCGAGTTGGACGTGGGTTCTTG
ATCATTGAATCCAGCATTTGCGTCGCCGTGATAACCACTTTACGTGCACGGTTACATTTCTCGATCATCA
TCTTTTGAGCGAAGATAACTTCTTCTGCTGGGATTTCTACACCTAGGTCGCCACGTGCAACCATGATGCC
GTCAGACAGCTCAAGGATCTCATCGAAGTTGTCCAAGCCTTCTTGGTTTTCGATTTTAGAGATGATTTGA
ATGTTTTGACCGCCGTGAGAAGCTAATACTTCACGGATTTCTTTCACGTCAGAACCTTTACGGATGAAAG
AGGCAGCAACGAAATCAACGCCTTGCTCACAACCAAATTTCAGGTCGTTTTTGTCTTTTTCAGACAGCGC
TGGCAGATTGACAGAAACGCCTGGCAGGTTAACACCTTTGTTTTCACCCAGAGCGCCGTTGTTCAGAACT
TTACACTTCACTTCAGTGTCAGTGGTCGCCAGTACTTCCATCTCTATAAGACCGTCGTCAACCAGAATAC
GGTTGCCCACGTTCAGGTCTTTTGCAAAACCAGAGTAAGTGACTGCTACGCGCTCTTTGTTACCAACAAC
TTTCGTGTCAGTTGTGAAAGTGAACTCTTGGCCAGCGACCAGATCCACATCGTCACCGTTTTCCAGCTTG
ATAGTACGGATCTCTGGACCTTTAGTATCCAGTAGGATCGCCAGTTGTTTACCGGTCACTTCCATCACTT
TACGGAAGTTAGTGATACGAGTGCCGTGTTCAACGTAGTCACCGTGAGAGAAGTTGAGACGCATAACATT
CATGCCAGCGTTTACAAGCTCAGTCAGTTTCTCTACAGACTCAGTTTTTGGGCCAATCGTACATACGATT
TTGGTCTTTTTCA
Protein Sequence 
>gi|147674848|ref|YP_001216011.1| pyruvate kinase [Vibrio cholerae O395] MKKTKIVCTIGPKTESVEKLTELVNAGMNVMRLNFSHGDYVEHGTRITNFRKVMEVTGKQLAILLDTKGPEIRTIKLENGDDVDLVAGQEFTFTTDTKVVGNKERVAVTYSGFAKDLNVGNRILVDDGLIEMEVLATTDTEVKCKVLNNGALGENKGVNLPGVSVNLPALSEKDKNDLKFGCEQGVDFVAASFIRKGSDVKEIREVLASHGGQNIQIISKIENQEGLDNFDEILELSDGIMVARGDLGVEIPAEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAIMDGTDAVMLSGETAKGKYPVEAVKIMAQIAERTDPVLKAELGSRLDSPRLRITEAVCKGAVDTAEKLAAPLIIVATEAGKSARSVRKYFPTANIIAVTTNKKTAAQLVLSKGVTPVVVDAIDNTDAFYHLGKEIALQSGLGKKGDIVVMVSGALVASGTTNTASVHVL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pykF mutant is attenuated in mice (Merrell et al., 2002).
COG COG0469G, under G: Carbohydrate transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].