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VC1173

Victor ID 2450
Gene Name VC1173
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2614606
NCBI Protein GI 15641186
Locus Tag VC1173
Genbank Accession AE003852
Protein Accession NP_230818
Other Database IDs UniProtKB-ID: TRPG_VIBCH
UniRef100: UniRef100_Q9KST3
UniRef90: UniRef90_Q9KST3
UniRef50: UniRef50_A6WPW9
UniParc: UPI0000137633
EMBL: AE003852
EMBL-CDS: AAF94332.1
RefSeq_NT: NC_002505.1
GenomeReviews: AE003852_GR
KEGG: vch:VC1173
TIGR: VC_1173
HOGENOM: HBG292341
OMA: YGGKVER
ProtClustDB: PRK05670
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 1246718
Gene Ending Position 1247329
Gene Strand (Orientation) -
Protein Name anthranilate synthase component II
Protein pI 5.78
Protein Weight 19825.09
Protein Length 203
Protein Note TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity
DNA Sequence 
>gi|15640032:1246718-1247329 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
GTTACGCGAATTGAGTCTGCGCTGGCGTTGAAGACAATGCCCAATCAATGGCATTGGCCAGCAAGGTAGC
GCCGTGGGTGGTCATGATCGATTCTGGGTGAAATTGAAAGCCGCAGACTTTGTCAGCCTCATTAACCACC
GACATCACGAGTCCGTTCACTTCTGCCGTCACGGTCAGTGCTGATGGAACTTGCGTGGCGACCAGTGAGT
GGTAACGTGCGATCGCCAACGGTGAAGGGAGACCGCGATAAATCGCGTGGTTTTGGTGCTCCATCATCGA
TACTTTACCGTGGATGATTTCACCCGCGCCAGCAACCACACCGCCGTAGGCTTCCACGATGGCTTGATGC
CCTAAGCAGATACCAATCATTGGCACTTTGCCTTTCAGGCGTTGCAGCAGCTCTGGCATGCAGCCCGTTT
CAGACGGCGCACCTGGCCCGGGGGATAACACGACCACAGGATTATCCAGTTGCAGCAGCGCTTGCTCGAT
AGCATCCGCAGAAAGGTTATTGCGATAAATCGTGACCACGTGACCGAGTGAGCGAAACTGATCCACCAAG
TTATAAGTGAAGGAGTCAAAGTTATCGATAAACAGAATATTGGCCATGATCA
Protein Sequence 
>gi|15641186|ref|NP_230818.1| anthranilate synthase component II [Vibrio cholerae O1 biovar El Tor str. N16961]
MIMANILFIDNFDSFTYNLVDQFRSLGHVVTIYRNNLSADAIEQALLQLDNPVVVLSPGPGAPSETGCMP
ELLQRLKGKVPMIGICLGHQAIVEAYGGVVAGAGEIIHGKVSMMEHQNHAIYRGLPSPLAIARYHSLVAT
QVPSALTVTAEVNGLVMSVVNEADKVCGFQFHPESIMTTHGATLLANAIDWALSSTPAQTQFA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC1173 mutant is attenuated in mice (Merrell et al., 2002).
COG COG0512EH, under E: Amino acid transport and metabolism; H: Coenzyme transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].