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VC0251

Victor ID 2431
Gene Name VC0251
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2614274
NCBI Protein GI 15640281
Locus Tag VC0251
Genbank Accession AE003852
Protein Accession NP_229908
Other Database IDs UniProtKB-ID: Q9KV99_VIBCH
UniRef100: UniRef100_A5F3X2
UniRef90: UniRef90_A5F3X2
UniRef50: UniRef50_A5F3X2
UniParc: UPI00000C2C43
EMBL: AE003852
EMBL-CDS: AAF93427.1
RefSeq_NT: NC_002505.1
GenomeReviews: AE003852_GR
KEGG: vch:VC0251
TIGR: VC_0251
HOGENOM: HBG264485
ProtClustDB: CLSK793544
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 257291
Gene Ending Position 259768
Gene Strand (Orientation) +
Protein Name acyl protein synthase/acyl-CoA reductase RfbN
Protein pI 7.61
Protein Weight 85869.79
Protein Length 825
Protein Note similar to GB:X59554 PID:48393; identified by sequence similarity; putative
DNA Sequence 
>gi|15640032:257291-259768 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
AATGCCTGTAAATAACGAAAATCTGACCAGTGTACTTGATGCTCGCCCTTTTGAATTATCAGAAGAGCAA
AAATCTCCACTATTTAAAGCGAACTTACTTGCAGAGTTAGTACATCATTATCAATGCAACGAGATGTATC
GCAAATTTTGTCAAAAAAACAAATTTGACCCTTTGGTATTTGATGGTGAGGTTGCAGATATTCCACCCAT
ACCTGTGCACATCTTCAAAGCAATAGGACATAAATTATCTTCGGTAAGCGATGATACGATAAAAGCGAAG
CTTCAATCTTCTGCTACCAGTGGCGTACCCAGTACCATATTGTTAGATAAGGTAACCGCTCGTCGACAGA
CTCGAGCAATGGCAAGAGTTATGCAGGAGGTGTTGGGGCCTAAACGTCGCCCGTTTTGCATTATGGATAT
TGATCCGACAAGCCCAAATGCCACTAACCTTGGGGCTCGTATTGCGGCGGTAAAAGGTTACCTAAACTTC
GCCTCAACATCGAAGTATTTTATAGATGCTGATAGCCCAAGTGCTCCACTTGAATTTCTGGAGCAAAAGT
TTGTTGAACATCTGAATTCACTTGCGAGTGAAGAGCCGCTCATAATTTTTGGATTCACGTTTGTACTTTA
TCACACGGTTTTTAAGACCCTTAAAGACAAGGGGATCTCGTTTCAATTGCCTAAAGGTTCTCAGGTTATT
CATATTGGTGGTTGGAAAAAACTTGAGTCAGAGAAGGTGGATAAAATTACCTTTAATCGAGATATCGCCT
CAGTATTGGGTATTTCTCCTGATGATGTTGTGGATATCTATGGTTTCACTGAACAGATGGGGCTTAATTA
CCCAGATTGTAAAGCAGGATGGAAACATATTCATGCCTATTCTGACGTAATTATTCGTGATGAATCGAAC
CTAGAAGTGTGTGGGCCAGGTAAAGTAGGCTTACTTGAGTTTGTAAGCCCACTACCGCATTCATATCCGG
GGAATGTTGTACTTACAGATGACCTTGGTGTGATTGAAGAAAGTCTTTGTGAGTGTGGTAAAGCTGGAAA
AAGATTCAAAGTCATTGGACGAGCAAAAAAAGCAGAAGTAAGAGGCTGTGGTGATGTTATGTCTGAGAAA
TTGACTAAAAAGCCATCGTATAAGCCACTTTCTCAACAAGAAGAGAGGTTGACTATCTACCACTCACCGA
TATTTCTCGATGATACTATGTCCGCATCTCAGCAGCTTGATCAAATCTTTTGTTCTTTAAAGAGGAAGCA
AAAATGGCTGGCTAACCAACCATTAGAAGCTATTCTTGGTTTAATCAATGAAGCGCGCAAAAGCTGGTCG
AGTACGCCGGAGCTTGACCCTTATCGACATACTGGATTGAACTTCCTAGCTGATTGGTGTGAACCCAATC
GTTTGAAAAACCTGCTTGATTCAGCATTGAATGGTCAGCGAGCTTTTTTGGATAATTTTTTACCTCGTAA
AGATATTAGCCATAGCTCTCAAAAAGCAATGCCAAGAGGTATCGTATCTCACTGGCTGTCGGGTAACGTA
CCGTTACTCGGCATGTTTGCGCTGGTACAGAGTATTTTAAGTAAAAATGCCAACATTCTGAAAGTTTCAG
CAAGCGAATCGCAAGCTTTGCCAGTATTATTGGCGACTTTTAAAGGCCTTAGCTACACTACCCCAGGTGG
TTACACTATCCACGGTGATGACTTATTAGGGACTCTCGCTGTTGTATATTTTGATCGACACCAAACTAAA
ATTGCAGAGAAGTTTTCGGCCAATGCTGATGTGCGTATAGCTTGGGGGGGACGAGAGGCAATCGAGTCTG
TAAGTGGCCTTCCAAAGAAATATAATAGTCAAGATATCCTCTTTGGACCTAAGCTTTCTATGATGGTTGT
TGGCAGCGATGCTCTAGACTCTGACAAGGCAATCAGAAAGTTGATTCGTCGGGCTGCAACTGACTCTAGT
GTGTTCGATCAGTTTGCTTGCGCTTCTCCGCACACCATTTTTGTTGAGAAGGGCGGTCTAATAACACCTA
AAGAGTTTGCAGAGAAGCTTGCCTCAGCAATGGATAAGGCTCTTGTACGCTTACCAACTCAAGTACCAGA
CATTGGGCAAGCAAATAAGATTCGCTCAAAGATAGCGGAATATGCATTTATTGGCGAATATTGGCATGAC
AAGCACTTACGTTGGACGGTGTTGTTTGATGAAGGGATAGAGCTTGTTGAGCCGACATATCAACGTGTTA
TTACAGTAAAAGCAGTTGATAATGTATTTGATGTAGTCGACAGTGTACATGAAGATATCCAAACGGTCGG
GTTGGCGATGAATGGTGAAAAGCGTCTTCGTTTTGCTAACGAGATAATGTTAAAAGGTGCGATGCGATGT
CCAGATGTCGGCTACATGACCCATTTTGATTCCCCATGGGATGGGGTTGTAGCGCTAGATAGAATGGTTC
GTTGGGTAACTCTAGGAGGACCGCTGTG
Protein Sequence 
>gi|15640281|ref|NP_229908.1| acyl protein synthase/acyl-CoA reductase RfbN [Vibrio cholerae O1 biovar El Tor str. N16961]
MPVNNENLTSVLDARPFELSEEQKSPLFKANLLAELVHHYQCNEMYRKFCQKNKFDPLVFDGEVADIPPI
PVHIFKAIGHKLSSVSDDTIKAKLQSSATSGVPSTILLDKVTARRQTRAMARVMQEVLGPKRRPFCIMDI
DPTSPNATNLGARIAAVKGYLNFASTSKYFIDADSPSAPLEFLEQKFVEHLNSLASEEPLIIFGFTFVLY
HTVFKTLKDKGISFQLPKGSQVIHIGGWKKLESEKVDKITFNRDIASVLGISPDDVVDIYGFTEQMGLNY
PDCKAGWKHIHAYSDVIIRDESNLEVCGPGKVGLLEFVSPLPHSYPGNVVLTDDLGVIEESLCECGKAGK
RFKVIGRAKKAEVRGCGDVMSEKLTKKPSYKPLSQQEERLTIYHSPIFLDDTMSASQQLDQIFCSLKRKQ
KWLANQPLEAILGLINEARKSWSSTPELDPYRHTGLNFLADWCEPNRLKNLLDSALNGQRAFLDNFLPRK
DISHSSQKAMPRGIVSHWLSGNVPLLGMFALVQSILSKNANILKVSASESQALPVLLATFKGLSYTTPGG
YTIHGDDLLGTLAVVYFDRHQTKIAEKFSANADVRIAWGGREAIESVSGLPKKYNSQDILFGPKLSMMVV
GSDALDSDKAIRKLIRRAATDSSVFDQFACASPHTIFVEKGGLITPKEFAEKLASAMDKALVRLPTQVPD
IGQANKIRSKIAEYAFIGEYWHDKHLRWTVLFDEGIELVEPTYQRVITVKAVDNVFDVVDSVHEDIQTVG
LAMNGEKRLRFANEIMLKGAMRCPDVGYMTHFDSPWDGVVALDRMVRWVTLGGPL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC0251 mutant is attenuated in mice (Merrell et al., 2002).
COG COG1541H, under H: Coenzyme transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].