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VC1098

Victor ID 2436
Gene Name VC1098
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2614368
NCBI Protein GI 15641111
Locus Tag VC1098
Genbank Accession AE003852
Protein Accession NP_230743
Other Database IDs UniProtKB-ID: ACKA1_VIBCH
UniRef100: UniRef100_Q9KT07
UniRef90: UniRef90_Q9KT07
UniRef50: UniRef50_Q65TV4
UniParc: UPI00000C2E9B
EMBL: AE003852
EMBL-CDS: AAF94257.1
RefSeq_NT: NC_002505.1
GenomeReviews: AE003852_GR
KEGG: vch:VC1098
TIGR: VC_1098
HOGENOM: HBG285863
OMA: PHLKDKN
ProtClustDB: PRK00180
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 1167746
Gene Ending Position 1168942
Gene Strand (Orientation) -
Protein Name acetate kinase
Protein pI 5.82
Protein Weight 40560
Protein Length 398
Protein Note AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA
DNA Sequence 
>gi|15640032:1167746-1168942 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
ATTAGATGTTCGTCAGACGAGCTGTATCTTCTGCAATCACTAACTCTTCGTTAGTCGCGATAACCATCGC
TGGGATACGGCTGTCTGCAGTGGTGATCACACCTTCACCGCCGAAACGGGCTTTCAGGTTTGCTGCGCTG
TCAACGGTGATACCGAAAATCGCTAGACGGTTCAGAACCATTTCACGGATTGGCGCAGAGTTTTCACCGA
TACCACCAGTGAAGGTGATCGCGTCCAGACGGCCGTCTAGGCTTGCTGTGTAGCCAGCAACGTATTTCGC
TAGGCGGTGACAGAATACGTCCATTGCGCGAGTTGCTTCTTCTTTTTGGCCGTAGTTGTCTTCAACGAAA
CGGCAGTCAGAAGTCACTTCAGTCAGACCCAACAGACCCGATTCTTTGGTCAGCATGGTGTTGATTTTCT
CAACTGAGTAACCCAGCGTGTCGTGCAGGTGGAAAATGATCGCAGGATCGATATCACCACAACGAGTACC
CATCACCAGACCTTCCAGTGGAGTCAGACCCATAGATGTGTCAACCGATTGGCCGTTTTTGATCGCACAC
ACAGAAGCACCGTTGCCTAGGTGGCAGTTGATGATGTTCAGTTCGTTTGCAGGTTTGCCCAGACGCTCAG
CCGCTTCACGTGCGATGAACAGGTGAGACGTACCGTGCATGCCGTAGCGACGAATACCGTGCTCTTTGTA
CAGGTTGTATGGCAGAGCGTACAGGTACGCTTCTTCTGGCATTGTTTGGTGGAACGCAGTGTCGAATACC
GCAACATTTTTCAGCTCTGGGAACGCTTTTTGCGCCGCTTTGATACCGATGATGTGTGCTGGGTTGTGCA
GTGGAGCGAGTGCTGCACAATCTTCGATGCCTTTCAGTACAGCGTCGTCAATCAGTGCAGATTGAGTGAA
CTGCTCACCACCGTGTACCACGCGGTGACCGATCGCTTTCAGTTGAGCTGCCAGTTCTGGTTTAGAAGCA
AGAATAGTTTCAACGATGAAAGACAGAGCTTCATCGTGTGCAGCGCCTTCGCCCAGTTGAGCTTCGTGCT
TGCCGTCCAATTTCCACTTGATACGAGCTTCAGGAAGGTGTAAACATTCAGCGAGACCTGAAAGATGTTG
TTCACCGCTTTGAGCGTCAACAACTGCGAACTTAAGTGAAGAACTACCGCAGTTTAAAACTAAAACCAGC
TTAGACA
Protein Sequence 
>gi|15641111|ref|NP_230743.1| acetate kinase [Vibrio cholerae O1 biovar El Tor str. N16961]
MSKLVLVLNCGSSSLKFAVVDAQSGEQHLSGLAECLHLPEARIKWKLDGKHEAQLGEGAAHDEALSFIVE
TILASKPELAAQLKAIGHRVVHGGEQFTQSALIDDAVLKGIEDCAALAPLHNPAHIIGIKAAQKAFPELK
NVAVFDTAFHQTMPEEAYLYALPYNLYKEHGIRRYGMHGTSHLFIAREAAERLGKPANELNIINCHLGNG
ASVCAIKNGQSVDTSMGLTPLEGLVMGTRCGDIDPAIIFHLHDTLGYSVEKINTMLTKESGLLGLTEVTS
DCRFVEDNYGQKEEATRAMDVFCHRLAKYVAGYTASLDGRLDAITFTGGIGENSAPIREMVLNRLAIFGI
TVDSAANLKARFGGEGVITTADSRIPAMVIATNEELVIAEDTARLTNI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC1098 mutant is attenuated in mice (Merrell et al., 2002).
COG COG0282C, under C: Energy production and conversion
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].