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toxR

Victor ID 2342
Gene Name toxR
Sequence Strain (Species/Organism) Vibrio cholerae O395
NCBI Gene ID 5136021
NCBI Protein GI 147674563
Locus Tag VC0395_A0505
Protein Accession YP_001216456.1
Taxonomy ID 345073
Chromosome No 2
Gene Starting Position 537864
Gene Ending Position 538748
Gene Strand (Orientation) -
Protein Name cholera toxin transcriptional activator
DNA Sequence 
>gi|147673035:537864-538748 Vibrio cholerae O395 chromosome 2, complete sequence
CCTACTCACACACTTTGATGGCATCGTTAGGGTTAGCAACGATGCGTAAGGTTATGTTTTCCCCTGAAAC
TTCAGGGCTGTGAATGTAATTCAGCGTTAACTGGTTATTTTGTCCACCAGTGGCAATCACTTCTATCGGC
TTGAGTCCACCAGTATGTTTTTCATTGTATTTTTTAACGCACAGTTCGATTGACGGTAGCCAATTTGAAA
GATCAGGGTGGTTATTCGGCATATTGACGGCTACGCCATCGACAACCGTTAGGGGTTTAAAGCTGGATTG
GCTTGGGTTAGTGAGCAGTAATACTGCGAGGGGAAGTAAGACCGCTATCAGAATAAACAGTCGATTCCCC
AAGTTTGGAGCCGATTTATTCGCCACGACATTGGCTGGCTGCGGTGTGTTCACTACAGTGGCTGATGAAG
GCACACTGCTTGATTCTGCGTATTCATTGACAGATTCTGGCTGAGAGATGTCATGAGCAGCTTCGTTTTC
GCGAGCCATCTCTTCTTCAACCGTTTCCACTCGGGCGATCAATTGGTAACCGCGCTTCGGAACCGTTTTG
ACGTATTGTGGGGACTTTGTCGAATCTTTGAGCATTTTGCGCAGAGTCGAAATGGCTTGGGTTAAGCTGG
AATCATCGACTTCAAAACCTTGCTCTCGCCAAACAAAGTCATGCAAATCATTGCGAGAAATCACCTCGTT
TGGACGTTGGGCCAGCAGCCAAAGAATTCGGCTTTCGTTGCTGCCTAATCGAATGATCTCTTCACTATCT
TCTTTGTCAATCAGAGTATTGCTTAGGGGATCGAAGGTAAATTTTTCAGCAAGAATGAATTTAGTACCAA
TATGACTCATCGATATCTCTTTTGAGTTGTGTCCTAATCCGAACA
Protein Sequence 
>gi|147674563|ref|YP_001216456.1| cholera toxin transcriptional activator [Vibrio cholerae O395] MFGLGHNSKEISMSHIGTKFILAEKFTFDPLSNTLIDKEDSEEIIRLGSNESRILWLLAQRPNEVISRNDLHDFVWREQGFEVDDSSLTQAISTLRKMLKDSTKSPQYVKTVPKRGYQLIARVETVEEEMARENEAAHDISQPESVNEYAESSSVPSSATVVNTPQPANVVANKSAPNLGNRLFILIAVLLPLAVLLLTNPSQSSFKPLTVVDGVAVNMPNNHPDLSNWLPSIELCVKKYNEKHTGGLKPIEVIATGGQNNQLTLNYIHSPEVSGENITLRIVANPNDAIKVCE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: toxR mutant is attenuated in mice (Taylor et al., 1987).
COG COG3710K, under K: Transcription
References
Taylor et al., 1987: Taylor RK, Miller VL, Furlong DB, Mekalanos JJ. Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin. Proceedings of the National Academy of Sciences of the United States of America. 1987; 84(9); 2833-2837. [PubMed: 2883655].