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VC0212

Victor ID 2452
Gene Name VC0212
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2614702
NCBI Protein GI 15640242
Locus Tag VC0212
Genbank Accession HB970497
Protein Accession NP_229869
Other Database IDs UniProtKB-ID: Q9KVD4_VIBCH
UniRef100: UniRef100_C3NT02
UniRef90: UniRef90_A5F410
UniRef50: UniRef50_A5F410
UniParc: UPI00000C2C28
EMBL: AE003852
EMBL-CDS: AAF93388.1
RefSeq_NT: NC_002505.1
GenomeReviews: AE003852_GR
KEGG: vch:VC0212
TIGR: VC_0212
HOGENOM: HBG730280
OMA: MNEEIES
ProtClustDB: PRK08943
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 219396
Gene Ending Position 220373
Gene Strand (Orientation) -
Protein Name lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase
Protein pI 8.98
Protein Weight 35329.89
Protein Length 325
Protein Note Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA
DNA Sequence 
>gi|15640032:219396-220373 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
CTTAGCTTTGATCGCCATGATGGGAGTTGTCGTAAATTTCACTGCCATCACGCTGAGTTTTCAGCAACGA
CAAGTTCCACATGTACTGCTCCGGCTGTGGCGTGACCAGGGCTTCAATCGCACGGTTCATCGCCAGTGCA
TCGGCTTCTTCATCGCCAGTTGGGAAGTTTTGCAGCGCAGGCAAAATGTGCACTTCATAACGGCCTGAAT
CACTGTTGTAGCATGACATCAAAGGTACTACATGCGCTTTGCACAGCTTAGCCATTTTGCCAAACCCTTT
GAGCGTGGCTTTTTCGGTAGCAAAAAACGGTACAAACACGGAGTTTTGCGGGCCGTGATCTTCATCCGGT
ACCCAGTAGCCAACATAGCCGGATTGAATGGAACGCAAGAAAGGTTTGATGCCCGATTCGCGAGTAAAAA
TACGGCCACCATACTGCATACGTTGGACGTGCATCAGCCAATCGGCAATCGGGTTGCGCTGCGGTTTCAT
GATGTTGGCGACTTTGTAGCCGCGAGCCGCCAGCATAACGGCGGCGTAATCAATGGCCCAAGAGTGCGGG
ACTAACAAAATCACGCGCTCGCCGCTATCTAGCAGCGGCAGCAAGTTCTCTTCGCCAATCAGTTCGCCCC
GTGCGTTGTTGTAGCGGGTCGAGCGCACCAACAGCTCTGAATAACCGAGCATAAACTGCGAGGCTTTCAC
AAACGTATCGTGCAGGATCTGCTCGCGCTCTTGCTCGCTTTTCTCTGGAAAACAGTAGGCGAGGTTAACC
CGAGCGCGGCGGACTACGCGGCCATTTTTCTTGATGATGAGTGGCACCAAAGGTTTCGCCAGTCGATCAC
GCAAGCGCCAAGGAATAAAGGCTAACAGTGCTGCGAAAGCGATGCCAATCCAAGTGCCCCAGTGTTTGGG
GTGCAGAAAGCGCCACTCAAATTGCGGGTTATGTAGATGGCGTGCAATGCCGTTGTCTTGATCGCTCA
Protein Sequence 
>gi|15640242|ref|NP_229869.1| lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase [Vibrio cholerae O1 biovar El Tor str. N16961]
MSDQDNGIARHLHNPQFEWRFLHPKHWGTWIGIAFAALLAFIPWRLRDRLAKPLVPLIIKKNGRVVRRAR
VNLAYCFPEKSEQEREQILHDTFVKASQFMLGYSELLVRSTRYNNARGELIGEENLLPLLDSGERVILLV
PHSWAIDYAAVMLAARGYKVANIMKPQRNPIADWLMHVQRMQYGGRIFTRESGIKPFLRSIQSGYVGYWV
PDEDHGPQNSVFVPFFATEKATLKGFGKMAKLCKAHVVPLMSCYNSDSGRYEVHILPALQNFPTGDEEAD
ALAMNRAIEALVTPQPEQYMWNLSLLKTQRDGSEIYDNSHHGDQS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC0212 mutant is attenuated in mice (Merrell et al., 2002).
COG COG1560M, under M: Cell wall/membrane/envelope biogenesis
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].