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glyA-1

Victor ID 3860
Gene Name glyA-1
Sequence Strain (Species/Organism) Vibrio cholerae M66-2
NCBI Gene ID 7772176
NCBI Protein GI 227081115
Locus Tag VCM66_0897
Protein Accession YP_002809666.1
Other Database IDs UniProtKB-ID: C3LTI9_VIBCM
UniRef100: UniRef100_A5F2X8
UniRef90: UniRef90_Q7MN19
UniRef50: UniRef50_Q214H7
UniParc: UPI0000EF8F7F
EMBL: CP001233
EMBL-CDS: ACP05215.1
RefSeq_NT: NC_012578.1
GenomeReviews: CP001233_GR
KEGG: vcm:VCM66_0897
OMA: NINDEAV
ProtClustDB: PRK00011
Taxonomy ID 579112
Chromosome No I
Gene Starting Position 964243
Gene Ending Position 965550
Gene Strand (Orientation) +
Protein Name serine hydroxymethyltransferase
DNA Sequence 
>gi|227080237:964243-965550 Vibrio cholerae M66-2 chromosome I, complete genome
CGTGGAGTCATTGTGTGGTTTTTTTGCAATTTCAGTCAATCTGAGTCAGGAGATACAGATGCTTAAGCGT
GATATGAACATCGCTGATTACGATCCGGAGCTATACGCTGCCATTCAGGAAGAGACGCTTCGTCAAGAAG
AACATATTGAACTTATTGCTTCAGAAAACTACACCAGCCCGCGTGTAATGCAAGCACAAGGTTCTCAACT
GACCAACAAGTACGCCGAAGGTTATCCAGGTAAGCGTTACTATGGTGGTTGTGAGTACGTGGACAAAGCA
GAAGCTTTAGCGATTGATCGTGCTTGCCAACTGTTTGGCTGTGAATACGCGAACGTTCAGCCGCACTCTG
GATCTCAAGCGAACAGCGCTGTGTACATGGCGCTGCTCAACCCAAGTGACACCGTGCTAGGTATGAGCCT
TGCTCACGGTGGTCATTTGACTCACGGTTCACCGGTTAACTTCTCGGGCAAGCACTACAATGTGATCCCT
TACGGTATCGATGAAGCGGGTCAAATTAACTACGATGAAATGGAAGCCTTAGCACTGGAGCATAAGCCAA
AGATGATCATCGGTGGCTTCTCGGCTTACTCACAAATCGTGGATTGGAAACGCATGCGTGAAATTGCCGA
TAAAGTGGGTGCTTACCTGTTTGTTGACATGGCGCACGTTGCGGGTCTGATTGCGGCGGGTGTTTACCCA
AGCCCAGTGCCTTTTGCACACGTTGTCACGACCACCACGCATAAAACACTGGCAGGTCCACGCGGTGGCT
TGATCTTGTCAAATGCCGGTGAGGAGATGTACAAGAAGCTGAACTCTGCAGTATTCCCTGGCGGCCAAGG
CGGTCCTTTGATGCACGTGATTGCGGCAAAAGCGGTGGCGTTCAAAGAAGCGATGGAGCCTGAGTTTAAA
GAGTATCAAGCGCGTGTGGTGAAAAACGCCAAAGCCATGGTGGCGCAGTTCCAAGAGCGTGGTTACAAGA
TCGTCTCTAACAGCACGGAAAACCATTTGTTCCTTGTTGATCTGATTGATAAAAACATCACAGGTAAAGA
AGCAGATGCCGCTCTGGGCGCTGCCAATATCACGGTTAACAAGAACTCGGTACCAAATGACCCACGCAGC
CCGTTTGTGACTTCAGGTATCCGTGTCGGTACACCTGCAATCACTCGCCGTGGTTTTACTGAGCAAGACG
CAAAAGATCTCGCCAACTGGATGTGTGATGTTCTAGACAACATCAATGATCAAGGTGTGATTGAAGCGAC
GAAACAAAAAGTATTGGCGATCTGTCAACGTCTGCCTGTTTACGCTTA
Protein Sequence 
>gi|227081115|ref|YP_002809666.1| serine hydroxymethyltransferase [Vibrio cholerae M66-2] MESLCGFFAISVNLSQEIQMLKRDMNIADYDPELYAAIQEETLRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDKAEALAIDRACQLFGCEYANVQPHSGSQANSAVYMALLNPSDTVLGMSLAHGGHLTHGSPVNFSGKHYNVIPYGIDEAGQINYDEMEALALEHKPKMIIGGFSAYSQIVDWKRMREIADKVGAYLFVDMAHVAGLIAAGVYPSPVPFAHVVTTTTHKTLAGPRGGLILSNAGEEMYKKLNSAVFPGGQGGPLMHVIAAKAVAFKEAMEPEFKEYQARVVKNAKAMVAQFQERGYKIVSNSTENHLFLVDLIDKNITGKEADAALGAANITVNKNSVPNDPRSPFVTSGIRVGTPAITRRGFTEQDAKDLANWMCDVLDNINDQGVIEATKQKVLAICQRLPVYA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: glyA-1 mutant is attenuated in mice (Merrell et al., 2002).
COG COG0112E, under E: Amino acid transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].