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pykF from Vibrio cholerae M66-2

Victor ID 3850
Gene Name pykF from Vibrio cholerae M66-2
Sequence Strain (Species/Organism) Vibrio cholerae M66-2
NCBI Gene ID 7771756
NCBI Protein GI 227080695
Locus Tag VCM66_0470
Protein Accession YP_002809246.1
Other Database IDs UniProtKB-ID: C3LS02_VIBCM
UniRef100: UniRef100_A5F9F4
UniRef90: UniRef90_A5F9F4
UniRef50: UniRef50_Q54RF5
UniParc: UPI00000C2CE6
EMBL: CP001233
EMBL-CDS: ACP04795.1
RefSeq_NT: NC_012578.1
GenomeReviews: CP001233_GR
KEGG: vcm:VCM66_0470
OMA: TAHNVSK
ProtClustDB: PRK09206
Taxonomy ID 579112
Chromosome No I
Gene Starting Position 499500
Gene Ending Position 500912
Gene Strand (Orientation) -
Protein Name pyruvate kinase I
DNA Sequence 
>gi|227080237:499500-500912 Vibrio cholerae M66-2 chromosome I, complete genome
ATTACAGTACGTGTACTGATGCAGTGTTCGTTGTGCCAGAAGCAACCAGTGCGCCTGAAACCATCACTAC
GATGTCGCCTTTCTTGCCAAGGCCAGATTGCAGCGCAATCTCTTTACCTAGGTGGTAGAAAGCGTCAGTG
TTGTCAATCGCGTCAACCACAACTGGCGTTACACCTTTAGAAAGCACTAACTGAGCTGCTGTTTTCTTGT
TGGTGGTGACTGCAATAATGTTAGCCGTTGGGAAGTACTTACGAACTGAACGAGCAGATTTACCCGCTTC
AGTTGCTACGATGATCAGTGGCGCTGCCAGTTTCTCTGCGGTGTCTACTGCACCTTTACATACGGCTTCA
GTGATACGTAGACGTGGGCTGTCTAGGCGTGAACCCAGTTCTGCTTTCAGTACAGGGTCAGTACGCTCAG
CAATTTGCGCCATGATCTTCACCGCTTCAACTGGGTACTTACCTTTTGCTGTTTCGCCAGAAAGCATTAC
AGCATCAGTACCATCCATGATCGCGTTCGCAACGTCGCCCGCTTCTGCGCGAGTTGGACGTGGGTTCTTG
ATCATTGAATCCAGCATTTGCGTCGCCGTGATAACCACTTTACGTGCACGGTTACATTTCTCGATCATCA
TCTTTTGAGCGAAGATAACTTCTTCTGCTGGGATTTCTACACCTAGGTCGCCACGTGCAACCATGATGCC
GTCAGACAGCTCAAGGATCTCATCGAAGTTGTCCAAGCCTTCTTGGTTTTCGATTTTAGAGATGATTTGA
ATGTTTTGACCGCCGTGAGAAGCTAATACTTCACGGATTTCTTTCACGTCAGAACCTTTACGGATGAAAG
AGGCAGCAACGAAATCAACGCCTTGCTCACAACCAAATTTCAGGTCGTTTTTGTCTTTTTCAGACAGCGC
TGGCAGATTGACAGAAACGCCTGGCAGGTTAACACCTTTGTTTTCACCCAGAGCGCCGTTGTTCAGAACT
TTACACTTCACTTCAGTGTCAGTGGTCGCCAGTACTTCCATCTCTATAAGACCGTCGTCAACCAGAATAC
GGTTGCCCACGTTCAGGTCTTTTGCAAAACCAGAGTAAGTGACTGCTACGCGCTCTTTGTTACCAACAAC
TTTCGTGTCAGTTGTGAAAGTGAACTCTTGGCCAGCGACCAGATCCACATCGTCACCGTTTTCCAGCTTG
ATAGTACGGATCTCTGGACCTTTAGTATCCAGTAGGATCGCCAGTTGTTTACCGGTCACTTCCATCACTT
TACGGAAGTTAGTGATACGAGTGCCGTGTTCAACGTAGTCACCGTGAGAGAAGTTGAGACGCATAACATT
CATGCCAGCGTTTACAAGCTCAGTCAGTTTCTCTACAGACTCAGTTTTTGGGCCAATCGTACATACGATT
TTGGTCTTTTTCA
Protein Sequence 
>gi|227080695|ref|YP_002809246.1| pyruvate kinase [Vibrio cholerae M66-2] MKKTKIVCTIGPKTESVEKLTELVNAGMNVMRLNFSHGDYVEHGTRITNFRKVMEVTGKQLAILLDTKGPEIRTIKLENGDDVDLVAGQEFTFTTDTKVVGNKERVAVTYSGFAKDLNVGNRILVDDGLIEMEVLATTDTEVKCKVLNNGALGENKGVNLPGVSVNLPALSEKDKNDLKFGCEQGVDFVAASFIRKGSDVKEIREVLASHGGQNIQIISKIENQEGLDNFDEILELSDGIMVARGDLGVEIPAEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAIMDGTDAVMLSGETAKGKYPVEAVKIMAQIAERTDPVLKAELGSRLDSPRLRITEAVCKGAVDTAEKLAAPLIIVATEAGKSARSVRKYFPTANIIAVTTNKKTAAQLVLSKGVTPVVVDAIDNTDAFYHLGKEIALQSGLGKKGDIVVMVSGALVASGTTNTASVHVL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pykF mutant is attenuated in mice (Merrell et al., 2002).
COG COG0469G, under G: Carbohydrate transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].