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VC2320

Victor ID 2407
Gene Name VC2320
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2613116
NCBI Protein GI 15642318
Locus Tag VC2320
Genbank Accession AE003852
Protein Accession NP_231951
Other Database IDs UniProtKB-ID: Q9KPP6_VIBCH
UniRef100: UniRef100_C3LQ92
UniRef90: UniRef90_C3LQ92
UniRef50: UniRef50_A7K3N4
UniParc: UPI00000C3275
EMBL: AE003852
EMBL-CDS: AAF95464.1
RefSeq_NT: NC_002505.1
HSSP: P56255
GenomeReviews: AE003852_GR
KEGG: vch:VC2320
TIGR: VC_2320
HOGENOM: HBG576417
OMA: GANAGSF
ProtClustDB: CLSK874758
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 2468632
Gene Ending Position 2472258
Gene Strand (Orientation) -
Protein Name exodeoxyribonuclease V, 135 kDa subunit
Protein pI 5.21
Protein Weight 130301.88
Protein Length 1208
Protein Note similar to SP:P08394 GB:X04581 GB:X04582 PID:42682 PID:763090; identified by sequence similarity; putative
DNA Sequence 
>gi|15640032:2468632-2472258 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
ATCATAAATCAAGCTCCATCTGCCCAGCTTTACTCGCTCTTTGCGCCAACTCACGCCCTGCAATCAATCC
ATCCAACTCATCTAACAAGGCCAAACTTGGCTTGGTATGGAACACGCCCTGATCGCCGCGGCCATCCATC
CCGCGTAAAAAGAGATAAAACACGCCGCCGAAATGCTGCTCGTAATTGTAATGGGCTAAACGGCTGCGCA
AAAAGCGATGCAGCGCTAATGCATAAATTTGGTATTGCAGATCATAACGGTGCTCGGCCATCGCACTGCC
CAAACGCTGTGGATGATACGCCGCAGGATCGTCACCCAAATGGTTGGATTTCCAGTCCAGCACGTAATAG
CGCCCTTGATATTGAAACACCAGATCGATAAAGCCTTTGAGCATGCCTTGCACCGCATGAAAACCGAGAT
CGCCCGCGTGTGCCGAAAGCGGATCATGACGCTGGGTGATGCGATTCAGGGTTGGCGCATCCAACACTTC
GATCGGCAGTAAAAACTCCAACTCGGTCAGGCGCTGGGCGGCCATAATCTGTTGTAAGCGTAGCGCTTTA
CCATCCAGTGGCGTGCTCAATACGGTGTCAACCAACTGTTGCAACACCGGCAGCCACTCGCTTTCAATCT
GCTCACTTTCCATCAGTTCAAGGATGATTTTAGTATTGGGTTCACTGTGTGCCGATTGCTGGAAATCCAC
CTCTTCAAACAGCGAATGCAAGAACGTGCCGGGGCGTGCGCCACGCGGGAAATTGAAAATCGAGCGCTCG
ACAGATTCCAGCGCCGCTCCATCACGCTCTTGCGCACTATCAAGATCAAAACCGCCCACTTCAAGCAAGG
GCAACTCTTGCAAAGGATCATGGCGAGCATGACTTGATTGCATCACCAAGCCTGAGTAACTGGTCACTCG
CCAGCGGCGATCAATCGCTTGGCTTAACTCACGGGCAGTCAGCTCTCGCTCGTCCAATTGGGGTGGCTGA
TACGCTTGTTCGAAACGCTTCGGTGGCGGGCATTGCACGACATCTGGCAAGTTTTCACACTGCTTAAGCA
GCGCTTGCTGCAGATCCGCGATACCACCTTCTTGACCATCTTGCAGCAGAAACCCCATCGCACTACGATG
CGCCGAGGTCGGCTCTTGGCTCGAATTGCCGTTGCGCAGCGGCGCAATCCCAATAAAACAGCCATACACT
GCGCGAGTGAGCGCCACATACAGCAAGCGTAAATCTTCTGCCAAACGTTCTTGATCGGCTTTAGCTAACG
CCTCTTCATTGCCGGTTAAATCGACCCAAGTGGTGGCCGATTCAGCATCGTAATATTTGCCTTCACTGCT
CTCGCGATAGCTCATCACAAACGGCAAAAACACCAGCGGGTACTCAAGCCCTTTTGATTTGTGGATGGTA
ACAATCTGCACCAAGCGCCGCTCAGATTCGAGGCGCTGGATCTGCTCATCACTGCCCCCCAATCCTTGCG
CAGCATCCGCCATCGCCTGAGTCAGAAAACGCAGTAAGCCCTGATCGCTATCGATCTCACGCGTCGCTTG
CTGCAAGAGTTCGCTGATGTGCAGATAGTCGGTGAGCCAGCGCTCACCTTCACTTTCCGCCAGCCAACGT
TCGGCAATGTGGCGCTGAGTTAATACCGCACGCAGCATCGGCAATACGCCGCGCTCACTCCACAAACGGC
GATATTGGCGAAACTCCGCAATCAACTGTTCCCATTCGTTTTCATCGTTATTCAGCGCATCCAGCTCGCT
GGCGGTTAACGCAAACAGATTCGAAGCAACGGCCGCGCGTAACAAACGTTCATCTTCCGGCTGCCATACC
GCGAGCAGCAAGCGTTCAATATCTTGCGCCACATCGCTGGCAAACACGCTGTCACGGTTGGAAAGATACA
CACTGGCGATACCTTGCTGACTGAGCGCATCGCGCACCATGCGTGCTTCATTACCGGTGCGCACCAGCAC
CGCCAGATCGCCCGCTTCAATCGCCTCGCCGCGATGAAACGTTGCCGCGCCAGAGGCCGAAGCAGTCAAA
ATGTGCTGAATTTGCGCCGCACACGCCTCGGCCATTTGCGCGTAATAATCGGTTTTGCTTTGTGGTTTAT
CGAGATCTTCCGGCCACCAATAGGTCAAAGCTGGTTGTACTTGCCCCTCCAGTGACCAATGGCGTTTATC
AGCACCAGGGCTTGCCGCCACGGGCTGAAAGGGAATGTCATCACTGTAAATAAACGGATGAGTCGCAGAG
CTGAACACTTGGTTCACGGCCGCCACCATCGCTGCGCTGGATCGCCAGTTCGTGCCTAAGGTGTAGTGAG
CGTTCACCTGATTGCGCGCTTTGATGTAAGTGAAAATATCGGCGCCACGGAAAGCGTAAATCGCCTGTTT
CGGGTCGCCGATCATTAGCAAGCCACACTGCGGATAGTCCAGATACAGCCGACTGAAAATGCTGTACTGC
AGTGGGTCGGTATCTTGGAATTCGTCGATCATCGCCACCGGATACAGCGTGCGGATCCGCTCACCCAATA
GCCCTTGCTCATCATTATCGAGCGCAGCGCTGAGTTGAGTCAGCAAGTCATCAAACGAGAGCCAGTGATG
GGTAGATTTGGCTTTCGCCAACCAGTGACGACAGTGATGAATCGCATGCACCAAAAGTGGTGTTTTGAGT
GAAACAGGCTCAGCAAGAAATGCTTCTATTCGTTCAAACAGCGCTAATTGTGGCGGATTGCCTTTCTTTG
ATTTGGCAAGCAATCCGCTTTGGGTGAACTCTTCAAGCTCTGACGGCACGTGCAGATCGTGCGTTTCACT
TTGCGCCCAAGCATCCAGAATCGGCAAACGGCGCAGCAGCGCATTTTGGCTATTTTTGTGCAGGTCAGAG
CCAGTTACGGCGGGCTCAATCTCCTCTCGCTCCACTAACCAGTGCTGCTTAATCTCGCAAATGCGCGCTA
TCTGCGCTTGTTGCAGCGCAGCCAAATCCCCTTCCATTAAAGGCGTAGTCAGTTTGACTGGCGGCCCGGA
AAGATAACCGGCAATCTCAGCCAACAGCGCAGAGGGCGCCGGCCATAAGCGGCGCACTTCGCTCGCGAGG
GAAATGGGCAAGGGGTAGAACTGTCTGCGCCAATAATCGGCCACCACTTGCGCTTTGAGACGACTTTCAT
CGGTGACGAATTCATTTTCAAAGCGACTGCCCGATTCAAACGCATTTTGCGTCAGCATGCGTTGGCAAAA
ACCGTGGATGGTGAAAATGGCCGCTTCATCCATCTGTCGCTCGGCACTCAGCAACAAAGAGACGGCTAAG
TTGTGATCGGTAAATTCAGCCAGCAGGGAGCGAAGCAGTGGATCGTCACTCGCGCCGCGAGCAAAGGCGA
GGCGCGCATCGTGCAAGCGGCGACGAATACGGTCACGCAGCTCTGCGGTGGCCGCTTCGGTAAAAGTCAC
CACCAGAATTTGATCAACACTCAGTGGATGCGCGTGGCGAGTTTCCGCGCAGCCATGTCCAAGCACCAGA
CGCAGATACAGCCCTGCGATGGTATAGGTTTTTCCGGTGCCTGCCGAGGCTTCAATCAGCCGCGCTCCAT
GCAAGGGAAAGCGCAACGTATCGAGCGTAACAGCGAGCTTATTTGAATCGGCACTCA
Protein Sequence 
>gi|15642318|ref|NP_231951.1| exodeoxyribonuclease V, 135 kDa subunit [Vibrio cholerae O1 biovar El Tor str. N16961]
MSADSNKLAVTLDTLRFPLHGARLIEASAGTGKTYTIAGLYLRLVLGHGCAETRHAHPLSVDQILVVTFT
EAATAELRDRIRRRLHDARLAFARGASDDPLLRSLLAEFTDHNLAVSLLLSAERQMDEAAIFTIHGFCQR
MLTQNAFESGSRFENEFVTDESRLKAQVVADYWRRQFYPLPISLASEVRRLWPAPSALLAEIAGYLSGPP
VKLTTPLMEGDLAALQQAQIARICEIKQHWLVEREEIEPAVTGSDLHKNSQNALLRRLPILDAWAQSETH
DLHVPSELEEFTQSGLLAKSKKGNPPQLALFERIEAFLAEPVSLKTPLLVHAIHHCRHWLAKAKSTHHWL
SFDDLLTQLSAALDNDEQGLLGERIRTLYPVAMIDEFQDTDPLQYSIFSRLYLDYPQCGLLMIGDPKQAI
YAFRGADIFTYIKARNQVNAHYTLGTNWRSSAAMVAAVNQVFSSATHPFIYSDDIPFQPVAASPGADKRH
WSLEGQVQPALTYWWPEDLDKPQSKTDYYAQMAEACAAQIQHILTASASGAATFHRGEAIEAGDLAVLVR
TGNEARMVRDALSQQGIASVYLSNRDSVFASDVAQDIERLLLAVWQPEDERLLRAAVASNLFALTASELD
ALNNDENEWEQLIAEFRQYRRLWSERGVLPMLRAVLTQRHIAERWLAESEGERWLTDYLHISELLQQATR
EIDSDQGLLRFLTQAMADAAQGLGGSDEQIQRLESERRLVQIVTIHKSKGLEYPLVFLPFVMSYRESSEG
KYYDAESATTWVDLTGNEEALAKADQERLAEDLRLLYVALTRAVYGCFIGIAPLRNGNSSQEPTSAHRSA
MGFLLQDGQEGGIADLQQALLKQCENLPDVVQCPPPKRFEQAYQPPQLDERELTARELSQAIDRRWRVTS
YSGLVMQSSHARHDPLQELPLLEVGGFDLDSAQERDGAALESVERSIFNFPRGARPGTFLHSLFEEVDFQ
QSAHSEPNTKIILELMESEQIESEWLPVLQQLVDTVLSTPLDGKALRLQQIMAAQRLTELEFLLPIEVLD
APTLNRITQRHDPLSAHAGDLGFHAVQGMLKGFIDLVFQYQGRYYVLDWKSNHLGDDPAAYHPQRLGSAM
AEHRYDLQYQIYALALHRFLRSRLAHYNYEQHFGGVFYLFLRGMDGRGDQGVFHTKPSLALLDELDGLIA
GRELAQRASKAGQMELDL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC2320 mutant is attenuated in mice (Merrell et al., 2002).
COG COG1074L, under L: Replication, recombination and repair
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].