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VC1004

Victor ID 2429
Gene Name VC1004
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2614257
NCBI Protein GI 15641019
Locus Tag VC1004
Genbank Accession AE003852
Protein Accession NP_230650
Other Database IDs UniProtKB-ID: Q9KT99_VIBCH
UniRef100: UniRef100_C3LTQ2
UniRef90: UniRef90_A5F2R9
UniRef50: UniRef50_D7DHN3
UniParc: UPI00000C2E51
EMBL: AE003852
EMBL-CDS: AAF94165.1
RefSeq_NT: NC_002505.1
HSSP: P00496
GenomeReviews: AE003852_GR
KEGG: vch:VC1004
TIGR: VC_1004
HOGENOM: HBG392416
OMA: SYCTACF
ProtClustDB: PRK09246
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 1074352
Gene Ending Position 1075866
Gene Strand (Orientation) +
Protein Name amidophosphoribosyltransferase
Protein pI 6
Protein Weight 51531.85
Protein Length 504
Protein Note Catalyzes first step of the de novo purine nucleotide biosynthetic pathway
DNA Sequence 
>gi|15640032:1074352-1075866 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
CATGTGTGGTATTGTTGGAATCGTGGGTACAACGCCTGTAAACCAGTCAATTTATGACGCTTTGACGGTC
TTGCAGCATCGTGGCCAAGATGCCGCGGGTATTTGTACCATAGAAAGCAATCGTTTTCGTCTGCGTAAGG
CAAACGGATTAGTCAGGGATGTCTTTGAAGCGAAACACATGCAACGCCTGCAAGGCAACGTCGGGATCGG
CCATGTGCGTTACCCCACCGCAGGTAGCTCTAGCGCCTCAGAAGCTCAACCTTTCTATGTCAACTCTCCT
TTCGGTATCACACTTGCTCACAACGGTAATCTGACCAACGCGAACCAAGTGCGTCAAAAGCTGTTTGAAA
AAGACCGTCGTCATGTGAATACCACTTCGGATTCAGAGGTGTTGCTCAACGTACTGGCTCATGAAATTGA
TACCGTAAAGGGCAATGTCACCGCCGACGATGTGTTCCGTGCAATCAGCAATGTTCACCGTACCATTCGA
GGTGCTTATGCGGTGGCGGCGATGATCATTGGTCACGGTATGATTGCGTTTCGTGACCCACACGGTATTC
GACCATTGTGTCTCGGTAAGCGTGAAGTCAATGGTCAGCTCGAATATATGGTCGCCTCCGAATCGGTCGC
ACTGGATGCGGTTGGGTTCGACTTCGTGCGAGATGTCGCGCCCGGTGAAGCGATTTATGCCACTTTCGAC
GGTGAGCTCTACACCAAACAGTGTGCCGATAATCCAGCACTCAACCCATGCATCTTTGAATTTGTCTACT
TTGCGCGCCCTGATTCGTTTATCGACAAGATTTCTGTTTATAGCGCTCGTGTAGAGATGGGTAAGCGTTT
AGGTGAGCGCATCAAAAATGATTACAGCGATCTCGATATCGATGTAGTCATCCCGATTCCTGAAACCTCT
TGTGATATCGCCCTACAAATTGCACAGGCGATTGATAAACCATATCGCCAAGGCTTTGTTAAAAACCGCT
ATGTTGGCCGAACCTTTATCATGCCGGGTCAGCAGCAACGTAAGAAATCGGTACGCCGCAAACTCAATGC
GATTCGCTCAGAGTTTAAAGATAAAAACGTACTACTGGTGGATGATTCTATCGTGCGTGGCACTACCTCA
GAGCAGATCATTGAGATGGCTCGTGATTCTGGGGCGAAGAAAGTCTACATCGTCTCTGCTGCCCCTGAGA
TTCGCTTCCCGAACGTGTATGGTATTGATATGCCAAGTGCCAATGAGCTGATTGCTCATGGTCGTGATAA
CGATGCTATCTGTAAGCAGATTGGTGCCGATGCCTTGATATTCCAAACTTTAGAGGATTTGGTGGAAGCG
GTTCGCTGTGGCAACCCTGATATCGTCAAGTTTGAAGCTTCGGTCTTTAATGGCGAATACGTGACGGGTG
ACATCGATCAGCAGTACTTAGATTTTCTCGAGTCGATGCGCAGTGATGACGCGAAAGTGCAGCGTGAAAT
TCAACAAGATCTGGCTAACCTTGAGCTGCATAACGAAGGCGCTTA
Protein Sequence 
>gi|15641019|ref|NP_230650.1| amidophosphoribosyltransferase [Vibrio cholerae O1 biovar El Tor str. N16961]
MCGIVGIVGTTPVNQSIYDALTVLQHRGQDAAGICTIESNRFRLRKANGLVRDVFEAKHMQRLQGNVGIG
HVRYPTAGSSSASEAQPFYVNSPFGITLAHNGNLTNANQVRQKLFEKDRRHVNTTSDSEVLLNVLAHEID
TVKGNVTADDVFRAISNVHRTIRGAYAVAAMIIGHGMIAFRDPHGIRPLCLGKREVNGQLEYMVASESVA
LDAVGFDFVRDVAPGEAIYATFDGELYTKQCADNPALNPCIFEFVYFARPDSFIDKISVYSARVEMGKRL
GERIKNDYSDLDIDVVIPIPETSCDIALQIAQAIDKPYRQGFVKNRYVGRTFIMPGQQQRKKSVRRKLNA
IRSEFKDKNVLLVDDSIVRGTTSEQIIEMARDSGAKKVYIVSAAPEIRFPNVYGIDMPSANELIAHGRDN
DAICKQIGADALIFQTLEDLVEAVRCGNPDIVKFEASVFNGEYVTGDIDQQYLDFLESMRSDDAKVQREI
QQDLANLELHNEGA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC1004 mutant is attenuated in mice (Merrell et al., 2002).
COG COG0034F, under F: Nucleotide transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].