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VC2042

Victor ID 2414
Gene Name VC2042
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2613423
NCBI Protein GI 15642044
Locus Tag VC2042
Genbank Accession AE003852
Protein Accession NP_231676
Other Database IDs UniProtKB-ID: Q9KQF6_VIBCH
UniRef100: UniRef100_C3LNZ3
UniRef90: UniRef90_C3LNZ3
UniRef50: UniRef50_Q7MMB6
UniParc: UPI00000C31B2
EMBL: AE003852
EMBL-CDS: AAF95190.1
RefSeq_NT: NC_002505.1
GenomeReviews: AE003852_GR
KEGG: vch:VC2042
TIGR: VC_2042
HOGENOM: HBG290975
OMA: CHLAGGT
ProtClustDB: CLSK874650
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 2199636
Gene Ending Position 2200556
Gene Strand (Orientation) -
Protein Name histone deacetylase/AcuC/AphA family protein
Protein pI 5.63
Protein Weight 32337.32
Protein Length 306
Protein Note similar to SP:P28606 PID:580726 PID:669044 PID:669045; identified by sequence similarity; putative
DNA Sequence 
>gi|15640032:2199636-2200556 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
TTCAATACCCTGCGCTTAACGCCGCTTTCAGTAACTCAAGATGCAATGGCACGAGTGCCGTATGGTCTTC
GCGATACCCACCGCCTATGACACAAGCGATTGGAATGCTCTCCTGCTTTGCCAAACCCAACATAAAACGA
TCTCGTTGCGCGATAGCGGCCTGTGAAATGGATAAATAACCTAGCTCATCATCGTTATGAATATCCACAC
CGGCGTCATAGAGGATCAGATCAGGTCGATGGAGATTGACCGCCATTTCCACCACTTGGATGAAAGTGGA
CAAAAACTCTTCATCGCCCGTCTGGTTAGCATATCCGACATCCATACTAGAAGCAGGCTTACGCGCCGGA
AAATTCTTATCACAGTGAAAAGAGAGCGTAATGATCTCGTCACGTTCCGCGCACAAGGTTGCCGTGCCGT
CACCATGATGTACATCACTGTCAATGATCAGAACTTTATCAACACTAGGCAAAGAGAGTGCGAAGTGCGC
GGCTATCGCCAGATCATTGAACAGACAGAAACCGCTACCAAAATCGGCGTGAGCATGGTGATAACCCCCA
CTGAGATGAATTGCCACCCCTGATTGCAACGCTTGCTCAACCGTGAGGCAGGTTCCTCCCACCGAGTACA
AAGTACGCTCAATCAGTGGTTTGCTCCAAGGAAATCCGATTCGACGCATCTTGGCCGCGGATAGCGTCCC
CTCGAGCAAAGCTTGCACATAATCTGGGTCATGCAATCGCGTGATGCGTGAAAGCTCGGCCGCAATGGGG
GTATGAAACTCGAAGCTCGCTTGCCATGCTTCACTTTGCTCTCTTTGACGCACAATCTCTTCGTAAAGCA
GGCGATACTTATTGATCGGATAACGATGCCCCACAGGCAAATCCAGTTGTGAATAAATAGGATGGTAAAT
CAGTGGGATCA
Protein Sequence 
>gi|15642044|ref|NP_231676.1| histone deacetylase/AcuC/AphA family protein [Vibrio cholerae O1 biovar El Tor str. N16961]
MIPLIYHPIYSQLDLPVGHRYPINKYRLLYEEIVRQREQSEAWQASFEFHTPIAAELSRITRLHDPDYVQ
ALLEGTLSAAKMRRIGFPWSKPLIERTLYSVGGTCLTVEQALQSGVAIHLSGGYHHAHADFGSGFCLFND
LAIAAHFALSLPSVDKVLIIDSDVHHGDGTATLCAERDEIITLSFHCDKNFPARKPASSMDVGYANQTGD
EEFLSTFIQVVEMAVNLHRPDLILYDAGVDIHNDDELGYLSISQAAIAQRDRFMLGLAKQESIPIACVIG
GGYREDHTALVPLHLELLKAALSAGY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aphA mutant is attenuated in mice (Kovacikova and Skorupski, 2001).
COG COG0123BQ, under B: Chromatin structure and dynamics; Q: Secondary metabolites biosynthesis, transport and catabolism
References
Kovacikova and Skorupski, 2001: Kovacikova G, Skorupski K. Overlapping binding sites for the virulence gene regulators AphA, AphB and cAMP-CRP at the Vibrio cholerae tcpPH promoter. Molecular microbiology. 2001; 41(2); 393-407. [PubMed: 11489126].