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VC0485

Victor ID 2465
Gene Name VC0485
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2615279
NCBI Protein GI 15640512
Locus Tag VC0485
Genbank Accession AE003852
Protein Accession NP_230139
Other Database IDs UniProtKB-ID: Q9KUN0_VIBCH
UniRef100: UniRef100_A5F9F4
UniRef90: UniRef90_A5F9F4
UniRef50: UniRef50_Q54RF5
UniParc: UPI00000C2CE6
EMBL: AE003852
EMBL-CDS: AAF93658.1
RefSeq_NT: NC_002505.1
HSSP: P14178
GenomeReviews: AE003852_GR
KEGG: vch:VC0485
TIGR: VC_0485
HOGENOM: HBG734376
OMA: TAHNVSK
ProtClustDB: PRK09206
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 514731
Gene Ending Position 516143
Gene Strand (Orientation) -
Protein Name pyruvate kinase
Protein pI 5.85
Protein Weight 45380.16
Protein Length 470
Protein Note catalyzes the formation of phosphoenolpyruvate from pyruvate
DNA Sequence 
>gi|15640032:514731-516143 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
ATTACAGTACGTGTACTGATGCAGTGTTCGTTGTGCCAGAAGCAACCAGTGCGCCTGAAACCATCACTAC
GATGTCGCCTTTCTTGCCAAGGCCAGATTGCAGCGCAATCTCTTTACCTAGGTGGTAGAAAGCGTCAGTG
TTGTCAATCGCGTCAACCACAACTGGCGTTACACCTTTAGAAAGCACTAACTGAGCTGCTGTTTTCTTGT
TGGTGGTGACTGCAATAATGTTAGCCGTTGGGAAGTACTTACGAACTGAACGAGCAGATTTACCCGCTTC
AGTTGCTACGATGATCAGTGGCGCTGCCAGTTTCTCTGCGGTGTCTACTGCACCTTTACATACGGCTTCA
GTGATACGTAGACGTGGGCTGTCTAGGCGTGAACCCAGTTCTGCTTTCAGTACAGGGTCAGTACGCTCAG
CAATTTGCGCCATGATCTTCACCGCTTCAACTGGGTACTTACCTTTTGCTGTTTCGCCAGAAAGCATTAC
AGCATCAGTACCATCCATGATCGCGTTCGCAACGTCGCCCGCTTCTGCGCGAGTTGGACGTGGGTTCTTG
ATCATTGAATCCAGCATTTGCGTCGCCGTGATAACCACTTTACGTGCACGGTTACATTTCTCGATCATCA
TCTTTTGAGCGAAGATAACTTCTTCTGCTGGGATTTCTACACCTAGGTCGCCACGTGCAACCATGATGCC
GTCAGACAGCTCAAGGATCTCATCGAAGTTGTCCAAGCCTTCTTGGTTTTCGATTTTAGAGATGATTTGA
ATGTTTTGACCGCCGTGAGAAGCTAATACTTCACGGATTTCTTTCACGTCAGAACCTTTACGGATGAAAG
AGGCAGCAACGAAATCAACGCCTTGCTCACAACCAAATTTCAGGTCGTTTTTGTCTTTTTCAGACAGCGC
TGGCAGATTGACAGAAACGCCTGGCAGGTTAACACCTTTGTTTTCACCCAGAGCGCCGTTGTTCAGAACT
TTACACTTCACTTCAGTGTCAGTGGTCGCCAGTACTTCCATCTCTATAAGACCGTCGTCAACCAGAATAC
GGTTGCCCACGTTCAGGTCTTTTGCAAAACCAGAGTAAGTGACTGCTACGCGCTCTTTGTTACCAACAAC
TTTCGTGTCAGTTGTGAAAGTGAACTCTTGGCCAGCGACCAGATCCACATCGTCACCGTTTTCCAGCTTG
ATAGTACGGATCTCTGGACCTTTAGTATCCAGTAGGATCGCCAGTTGTTTACCGGTCACTTCCATCACTT
TACGGAAGTTAGTGATACGAGTGCCGTGTTCAACGTAGTCACCGTGAGAGAAGTTGAGACGCATAACATT
CATGCCAGCGTTTACAAGCTCAGTCAGTTTCTCTACAGACTCAGTTTTTGGGCCAATCGTACATACGATT
TTGGTCTTTTTCA
Protein Sequence 
>gi|15640512|ref|NP_230139.1| pyruvate kinase [Vibrio cholerae O1 biovar El Tor str. N16961]
MKKTKIVCTIGPKTESVEKLTELVNAGMNVMRLNFSHGDYVEHGTRITNFRKVMEVTGKQLAILLDTKGP
EIRTIKLENGDDVDLVAGQEFTFTTDTKVVGNKERVAVTYSGFAKDLNVGNRILVDDGLIEMEVLATTDT
EVKCKVLNNGALGENKGVNLPGVSVNLPALSEKDKNDLKFGCEQGVDFVAASFIRKGSDVKEIREVLASH
GGQNIQIISKIENQEGLDNFDEILELSDGIMVARGDLGVEIPAEEVIFAQKMMIEKCNRARKVVITATQM
LDSMIKNPRPTRAEAGDVANAIMDGTDAVMLSGETAKGKYPVEAVKIMAQIAERTDPVLKAELGSRLDSP
RLRITEAVCKGAVDTAEKLAAPLIIVATEAGKSARSVRKYFPTANIIAVTTNKKTAAQLVLSKGVTPVVV
DAIDNTDAFYHLGKEIALQSGLGKKGDIVVMVSGALVASGTTNTASVHVL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC0485 mutant is attenuated in mice (Merrell et al., 2002).
COG COG0469G, under G: Carbohydrate transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].