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VC0249

Victor ID 2432
Gene Name VC0249
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2614277
NCBI Protein GI 15640279
Locus Tag VC0249
Genbank Accession AE003852
Protein Accession NP_229906
Other Database IDs UniProtKB-ID: Q06959_VIBCH
UniRef100: UniRef100_A5F3X0
UniRef90: UniRef90_A5F3X0
UniRef50: UniRef50_A5F3X0
UniParc: UPI00000D470B
EMBL: AE003852
EMBL: X59554
EMBL-CDS: AAF93425.1
EMBL-CDS: CAA42142.1
RefSeq_NT: NC_002505.1
GenomeReviews: AE003852_GR
KEGG: vch:VC0249
TIGR: VC_0249
HOGENOM: HBG264482
OMA: ETSFISW
ProtClustDB: CLSK793542
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 254752
Gene Ending Position 256167
Gene Strand (Orientation) +
Protein Name rfbL protein
Protein pI 5.99
Protein Weight 48107.77
Protein Length 471
Protein Note similar to GB:X59554 PID:48391; identified by sequence similarity; putative
DNA Sequence 
>gi|15640032:254752-256167 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
TATGTCTGTGGTTGAGAGAATATTTAACCATTCCGAGTCAAGACCGGATTGTATAGCGGTCTATGAAAAT
GATCGAACAATTAGTTATGAAAATCTTGCTTCGGATATAAAAAAAACTGCTGCCAAGTTAGTATCCTTAG
GTGTAACATCTGAGGATGCTGTACTTGTAAGATCTAATAATAGCTATAGTTTCATACTGCTTTATTTTTC
TATTCACTATGTCGGTGCTAAATTTGTTAATGTTGCTCCTGACTCAGACGTAAGCTACGTGTCTTTTATT
GAAGATAAAGTAAATCCAAAACTATTTATTGAAAAAAGCCAGGATTTTATTAGAAACATAGATAGTTATA
CATTTGATAATATATTTCCCCCTCAGGCGAGGGGGATCGCAGATATTATGTTCACGAGTGGTACTACTGG
TGAGCCGAAGGGAGTTTTGTTAAGCCATAAAAGTTTAGTGTTAGCAACTGAACACATTATATCTCATGTA
AAAAATACCAATGAAGATGTTGAGCTTTTGTTAATGCCACTAAGCCACTCATTTGCTATGGCTAGAATGA
GGACTAGTTTATTTGCAGGTGGTGCTATCGTAGTTGGCTGCTCTTTTAAGCAATTAAAGTCGGTATTCAA
AGCTATAGAGTTTTACAAAGTTACAGGGCTAGGTCTCGTTCCTTCGGCTTGGTCATATATTACTTTAATG
ACCAAAGACCTCATACGTAAGTATTCAGAACAGCTAAATTTTATAGAGTTCGGAAGTGCACACTTCCCTT
TCGAGGATAAAAAGCAGGTCGCAGAGTGGTTTCCAAACACTAATGTAGTTATGCACTATGGCTTAACGGA
AGTGTCTCGAGCAACTTTCATTGATTTTCATAATGATGATATCAACGCGGTTGGTCATAGATATCGCGGA
GCTGATTTTAAGATCATCGATAATAAAGGAGCGGAAGTAATTGAAGGAGAAGAGGGTGAAATCGTTTTTA
AAGCACCATGGATGTTGGATGGCTATTTTGAGAACAGCCAATTAACGTCAGATTGTTTTGTAGAAGGTTA
CTTTAAAACAGGTGATTTAGGCCGTGTTGTTGGGGACTACCTATTTTTAACAGGCCGCTTAAAAGAAATA
ATTAACGTTGGCGGCAAAAAAGTAAGCCCTGATCAGGTGGAGAAAGTATTATCCGAAGCTCTAGGTGTTC
AAGAATGTGCATGCGCTGCTTTATCAGATGCCAATATGGGTGAAGTGGTTCAAGCCTATATTGTTGTAAA
ATCTGGTTGGGATTGCGAAAATGTAATTTCAAATATAAAAGAGACCATAAATGGCCAGTTGCCGATGCAT
ATGAGGCCTAAAAAATATAGTATAGTCAGTGCTTTGCCAAAGACCGTTTCAGGGAAAGTGCAAAGATACA
AACTGTCTTCTGAATA
Protein Sequence 
>gi|15640279|ref|NP_229906.1| rfbL protein [Vibrio cholerae O1 biovar El Tor str. N16961]
MSVVERIFNHSESRPDCIAVYENDRTISYENLASDIKKTAAKLVSLGVTSEDAVLVRSNNSYSFILLYFS
IHYVGAKFVNVAPDSDVSYVSFIEDKVNPKLFIEKSQDFIRNIDSYTFDNIFPPQARGIADIMFTSGTTG
EPKGVLLSHKSLVLATEHIISHVKNTNEDVELLLMPLSHSFAMARMRTSLFAGGAIVVGCSFKQLKSVFK
AIEFYKVTGLGLVPSAWSYITLMTKDLIRKYSEQLNFIEFGSAHFPFEDKKQVAEWFPNTNVVMHYGLTE
VSRATFIDFHNDDINAVGHRYRGADFKIIDNKGAEVIEGEEGEIVFKAPWMLDGYFENSQLTSDCFVEGY
FKTGDLGRVVGDYLFLTGRLKEIINVGGKKVSPDQVEKVLSEALGVQECACAALSDANMGEVVQAYIVVK
SGWDCENVISNIKETINGQLPMHMRPKKYSIVSALPKTVSGKVQRYKLSSE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: rfbL mutant is attenuated in mice (Merrell et al., 2002).
COG COG0318IQ, under I: Lipid transport and metabolism; Q: Secondary metabolites biosynthesis, transport and catabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].