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tolB from Vibrio cholerae M66-2

Victor ID 3869
Gene Name tolB from Vibrio cholerae M66-2
Sequence Strain (Species/Organism) Vibrio cholerae M66-2
NCBI Gene ID 7773026
NCBI Protein GI 227081965
Locus Tag VCM66_1759
Protein Accession YP_002810516.1
Other Database IDs UniProtKB-ID: TOLB_VIBCM
UniRef100: UniRef100_A5F753
UniRef90: UniRef90_A5F753
UniRef50: UniRef50_Q3IJ16
UniParc: UPI00000C60B3
EMBL: CP001233
EMBL-CDS: ACP06065.1
RefSeq_NT: NC_012578.1
GenomeReviews: CP001233_GR
KEGG: vcm:VCM66_1759
OMA: RVADYDG
ProtClustDB: PRK04792
Taxonomy ID 579112
Chromosome No I
Gene Starting Position 1913509
Gene Ending Position 1914861
Gene Strand (Orientation) -
Protein Name tolB protein
DNA Sequence 
>gi|227080237:1913509-1914861 Vibrio cholerae M66-2 chromosome I, complete genome
GTTATAAAAACGGTGACCATGCTGGAGCACGAACGCGCCCATTGGTTGCCGGTAATCTTGCTTTAAAGCG
TCCATCAATGGATACCATCGACAAGACGTTGGCCTTATTGTAGATGGAGCTATAAATCACCATACCACCA
TTCGGCGCAATACTTGGGGACTCATCTAACAAGGTTTTTGTCAGAATCTGCATTGCCCCTGTTTCTAAAT
CCTGCTTCGCGAGATTGAAGCCGGAATCACTACGATTCACCATCACCAAGAATTTTCCATCCGGTGTAAT
TTGGCCACCCAAGTTTTGGCTACCTTGCCAAGTTAAACGCTTGGTTTCACCGCCGGATAAATTTACTTGA
TAAATCTGTGGTTTACCACCCCGATCTGAAGTGAAAATTAAAGATTTACCATCTGGATGCCAGAAAGGTT
CGGTGTTGTTGGAACGGCCACTAGTCACCTCTGTTAAGCGACGTGTAGCCAAGTCCATCGTGTAGACCTG
TAAATTACCAGTTTTTGATAAAACCAGCGCTAGCGTTTTACCATCTGGTGAGAATCTGGGTGCACCATTA
TGACGTGGGAATGACGTCAGCTTCTCTCGCTTCCCACTGTAGATGTTCATCATGTAAATTTCGGCTTGTC
CGTTTTGGAAACTCACGTAAGCCAAAGTCTGACCATCAGGTGACCAAGCAGGTGACATAAGCGGCTGCTT
AGAACGAAGTACAAGACGTTCGTTATAGCCGTCATAATCAGCAATTCTCAGTTGATAAGGATACGGATCC
TTATCATTGACCACAACGTAAGCGATGCGCGTTAAGAAGGCGCCGCGTTCACCGGTCAATTCCTCATAAA
CCAAGTCCGCAATACGGTGGGCATATTCACGCATTCTTGATGCAGGAACGGTCGCCACTTTATTAAACAA
AACATGATCTTTAGATAGCACCAATTGACCATCTTGAGACAGAGCTTTGCTTTGGCCTTGAGTCAGTTGT
CCACGCACAATGTCAACCAGTTGATAACTAATTACATAGCTACCTTCCGCATTTTGCGTGATCGTACCCG
TCAATAATGAATCGACCCCCATAGATGTCCATTTGCCAAAGTTAACCTGCTCTTCGCTATAAGGCGTCTG
TGGCATTTTGCTGGTCGGAACTGGGCTAAATTTACCACTGCGCTGTAAGTCAGAGGCAATCACCGCAGAA
ACGTCTTCAGGCAACTTGGTTGCGCCTTCCCATTTGAAAGGAACTATCGCAATCGGACGTGCAGAATCAA
TACCGTCAGTAATAACTAGCTCCAATGCTGCATTCGCAATATTGGAAAAACCGGTACCGATGAGCATCAA
AACAAAAACTAATCGCTTAAACA
Protein Sequence 
>gi|227081965|ref|YP_002810516.1| translocation protein TolB [Vibrio cholerae M66-2] MFKRLVFVLMLIGTGFSNIANAALELVITDGIDSARPIAIVPFKWEGATKLPEDVSAVIASDLQRSGKFSPVPTSKMPQTPYSEEQVNFGKWTSMGVDSLLTGTITQNAEGSYVISYQLVDIVRGQLTQGQSKALSQDGQLVLSKDHVLFNKVATVPASRMREYAHRIADLVYEELTGERGAFLTRIAYVVVNDKDPYPYQLRIADYDGYNERLVLRSKQPLMSPAWSPDGQTLAYVSFQNGQAEIYMMNIYSGKREKLTSFPRHNGAPRFSPDGKTLALVLSKTGNLQVYTMDLATRRLTEVTSGRSNNTEPFWHPDGKSLIFTSDRGGKPQIYQVNLSGGETKRLTWQGSQNLGGQITPDGKFLVMVNRSDSGFNLAKQDLETGAMQILTKTLLDESPSIAPNGGMVIYSSIYNKANVLSMVSIDGRFKARLPATNGRVRAPAWSPFL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: tolB mutant is attenuated in mice (Merrell et al., 2002).
COG COG0823U, under U: Intracellular trafficking, secretion, and vesicular transport
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].