Currently, Vctors includes 5304 Virulence Factors for
127 pathogens. The detailed curated data is shown below:
| Index |
Pathogen Name |
Disease |
No. of Virulence Factors |
| Bacteria |
| G+ Bacteria |
| 1 |
Bacillus anthracis |
Anthrax |
54 |
| 2 |
Clostridium botulinum |
Botulism |
7 |
| 3 |
Clostridium difficile |
antibiotic-associated diarrhoea (AAD) |
4 |
| 4 |
Clostridium perfringens |
Food poisioning, Gas gangrene |
10 |
| 5 |
Clostridium tetani |
Tetanus |
3 |
| 6 |
Corynebacterium diphtheriae |
Diphtheria |
3 |
| 7 |
Enterococcus spp. |
urinary tract infections, bacteremia, bacterial endocarditis, diverticulitis, and meningitis |
42 |
| 8 |
Listeria monocytogenes |
Listeriosis |
106 |
| 9 |
Mycobacterium avium |
|
1 |
| 10 |
Mycobacterium tuberculosis |
Tuberculosis |
360 |
| 11 |
Staphylococcus aureus |
Staph infections |
47 |
| 12 |
Streptococcus agalactiae |
Group B streptococcus (GBS) infection |
30 |
| 13 |
Streptococcus equi |
Strangles (also equine distemper) |
3 |
| 14 |
Streptococcus pneumoniae |
Pneumonia |
413 |
| 15 |
Streptococcus pyogenes |
Group A streptococcal infections, Strep throat, Scarlet fever |
77 |
| Subtotal |
|
|
1160 |
| G- Bacteria |
| 16 |
Acinetobacter baumannii |
|
4 |
| 17 |
Actinobacillus pleuropneumoniae |
porcine pleuropneumonia |
122 |
| 18 |
Aeromonas hydrophila |
|
1 |
| 19 |
Aeromonas salmonicida |
Furunculosis, Bald sea urchin disease |
9 |
| 20 |
Bartonella spp. |
Cat-scratch disease, endocarditis, trench fever |
14 |
| 21 |
Bordetella avium |
Bordetellosis |
6 |
| 22 |
Bordetella bronchiseptica |
Infectious bronchitis, kennel cough |
5 |
| 23 |
Bordetella pertussis |
Whooping Cough |
24 |
| 24 |
Borrelia burgdorferi |
Lyme Disease |
18 |
| 25 |
Brucella spp. |
Brucellosis |
439 |
| 26 |
Burkholderia mallei |
Glanders |
10 |
| 27 |
Burkholderia pseudomallei |
Melioidosis |
61 |
| 28 |
Campylobacter jejuni |
Campylobacterosis |
81 |
| 29 |
Chlamydia trachomatis |
Chlamydia |
2 |
| 30 |
Chlamydophila pneumoniae |
Pneumonia |
3 |
| 31 |
Coxiella burnetii |
Q fever |
1 |
| 32 |
Edwardsiella tarda |
|
1 |
| 33 |
Escherichia coli |
Hemorrhagic colitis |
569 |
| 34 |
Francisella tularensis |
Tularemia |
316 |
| 35 |
Haemophilus influenzae |
Meningitis |
52 |
| 36 |
Helicobacter pylori |
Ulcers |
90 |
| 37 |
Legionella pneumophila |
Legionnaires' disease, Pontiac Fever |
70 |
| 38 |
Leptospira spp. |
Leptospirosis |
3 |
| 39 |
Mannheimia haemolytica |
Bovine Respiratory Disease |
1 |
| 40 |
Mycoplasma gallisepticum |
Chronic respiratory disease |
3 |
| 41 |
Neisseria meningitidis |
Meningitis |
175 |
| 42 |
Pasteurella multocida |
Pasteurellosis, fowl cholera |
36 |
| 43 |
Pseudomonas aeruginosa |
Pseudomonas aeruginosa infection |
105 |
| 44 |
Rickettsia spp. |
|
1 |
| 45 |
Salmonella spp. |
Salmonellosis |
387 |
| 46 |
Shigella |
Shigellosis |
349 |
| 47 |
Vibrio cholerae |
Cholera |
199 |
| 48 |
Yersinia enterocolitica |
|
59 |
| 49 |
Yersinia pestis |
Plague |
238 |
| 50 |
Yersinia pseudotuberculosis |
|
33 |
| 51 |
Yersinia ruckeri |
Enteric redmouth disease |
1 |
| Subtotal |
|
|
3488 |
| Viruses |
| 52 |
porcine respiratory coronavirus |
|
1 |
| 53 |
African swine fever virus |
African swine fever |
5 |
| 54 |
Autographa californica nuclear polyhedrosis virus |
|
4 |
| 55 |
Bombyx mori nucleopolyhedrovirus |
|
2 |
| 56 |
Bovine herpesvirus 1 |
Infectious bovine rhinotracheitis |
7 |
| 57 |
Bovine herpesvirus 5 |
|
2 |
| 58 |
Bovine respiratory syncytial virus |
Respiratory Disease |
3 |
| 59 |
Chicken Anemia Virus |
Chicken infectious anemia, Blue wing disease, Anemia dermatitis syndrome, Hemorrhagic aplastic anemi |
1 |
| 60 |
Classical swine fever virus |
Classical swine fever, hog cholera |
6 |
| 61 |
Ebola virus |
Ebola hemorrhagic fever |
1 |
| 62 |
Ectromelia virus |
|
3 |
| 63 |
encephalomyocarditis virus |
|
1 |
| 64 |
Equid herpesvirus |
Equine Rhinopneumonitis |
6 |
| 65 |
Feline herpesvirus 1 |
Feline viral rhinotracheitis |
1 |
| 66 |
Feline immunodeficiency virus |
Feline AIDS |
2 |
| 67 |
Feline infectious peritonitis virus |
Feline infectious peritonitis (FIP) |
6 |
| 68 |
frog virus 3 |
|
1 |
| 69 |
Gallid herpesvirus 1 |
Avian infectious laryngotracheitis, Fowl Laryngotracheitis |
3 |
| 70 |
Hantavirus |
Hantavirus Pulmonary Syndrome |
1 |
| 71 |
Herpes simplex virus type 1 |
Herpes |
22 |
| 72 |
Human immunodeficiency virus |
Acquired Immunodeficiency Syndrome (AIDS) |
3 |
| 73 |
Human metapneumovirus |
Respiratory tract infection |
2 |
| 74 |
Human parainfluenza virus type 3 |
human parainfluenza |
1 |
| 75 |
Human Respiratory Syncytial Virus |
Respiratory tract disease |
1 |
| 76 |
Infectious hematopoietic necrosis virus |
Infectious hematopoietic necrosis |
1 |
| 77 |
infectious laryngotracheitis virus |
Infectious laryngotracheitis |
2 |
| 78 |
Influenza virus |
Influenza (flu) |
6 |
| 79 |
La Crosse virus |
La Crosse encephalitis |
1 |
| 80 |
Marek's disease virus |
Marek's disease |
3 |
| 81 |
Measles virus |
Measles |
3 |
| 82 |
murine cytomegalovirus |
|
1 |
| 83 |
Myxoma virus |
myxomatosis |
2 |
| 84 |
Newcastle disease virus |
Newcastle disease |
1 |
| 85 |
Nipah virus |
|
1 |
| 86 |
Orf Virus |
Orf disease, Sore mouth (Ovine Ecthyma) |
1 |
| 87 |
Pneumonia virus of mice |
|
1 |
| 88 |
Porcine circovirus 2 |
Postweaning multisystemic wasting syndrome |
2 |
| 89 |
Porcine respiratory and reproductive syndrome virus |
Porcine Reproductive and Respiratory Syndrome (PRRS), Blue-Ear Pig Disease |
1 |
| 90 |
Pseudorabies virus |
Aujeszky's disease |
12 |
| 91 |
Rabbit fibroma virus |
|
1 |
| 92 |
Rabies virus |
Rabies |
4 |
| 93 |
Rift valley fever virus |
Rift valley fever |
2 |
| 94 |
Ross River virus |
Ross river fever |
2 |
| 95 |
Rotavirus |
Gastroenteritis |
2 |
| 96 |
SARS-related coronavirus |
Severe Acute Respiratory Syndrome (SARS) |
5 |
| 97 |
Sheeppox virus |
Sheeppox |
1 |
| 98 |
Simian immunodeficiency virus |
Simian AIDS |
1 |
| 99 |
Sindbis virus |
sindbis fever |
1 |
| 100 |
Tick-borne Encephalitis Virus (TBEV) |
Tick-borne Encephalitis |
1 |
| 101 |
Vaccinia virus |
|
28 |
| 102 |
VEE Virus |
Venezuelan equine encephalitis |
2 |
| 103 |
West Nile virus |
West Nile fever |
1 |
| 104 |
Western equine encephalomyelitis virus |
Western equine encephalomyelitis (WEE) |
3 |
| 105 |
Yellow fever virus |
Yellow fever |
4 |
| Subtotal |
|
|
181 |
| Parasites |
| 106 |
Babesia bovis |
|
1 |
| 107 |
Cryptosporidium parvum |
Cryptosporidiosis |
1 |
| 108 |
Entamoeba histolytica |
Amoebiasis |
14 |
| 109 |
Fasciola hepatica |
|
2 |
| 110 |
Leishmania donovani |
Visceral leishmaniasis |
9 |
| 111 |
Leishmania infantum |
Infantile visceral leishmaniasis |
2 |
| 112 |
Leishmania major |
Cutaneous leishmaniasis |
11 |
| 113 |
Leishmania mexicana |
Leishmaniasis |
7 |
| 114 |
Plasmodium spp. |
Malaria |
21 |
| 115 |
Schistosoma mansoni |
|
1 |
| 116 |
Toxoplasma gondii |
Toxoplasmosis |
25 |
| 117 |
Trypanosoma brucei |
African trypanosomiasis (African Sleeping Sickness) |
3 |
| 118 |
Trypanosoma cruzi |
Chagas disease |
8 |
| Subtotal |
|
|
105 |
| Fungi |
| 119 |
Aspergillus fumigatus |
|
33 |
| 120 |
Candida albicans |
Thrush, Candidiasis, yeast infection |
120 |
| 121 |
Candida glabrata |
Tortulosis |
9 |
| 122 |
Coccidioides spp. |
Coccidioidomycosis (California disease, Desert rheumatism, San Joaquin valley fever, and Valley fev |
3 |
| 123 |
Cryptococcus neoformans |
|
186 |
| 124 |
Histoplasma capsulatum |
Histoplasmosis |
3 |
| 125 |
Saccharomyces cerevisiae |
|
6 |
| 126 |
Wangiella dermatitidis (Exophiala dermatitidis) |
|
4 |
| Subtotal |
|
|
364 |
| Other diseases |
| Total |
127 |
|
5304 |
