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Victors Search
Found 6 gene(s).
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| Victors ID |
Gene Name |
Sequence Strain (Species/Organism) |
NCBI Gene ID |
NCBI Nucleotide GI |
NCBI Protein GI |
Locus Tag |
Genbank Accession |
Protein Accession |
Protein Name |
Molecule Role |
Molecule Role Annotation |
PMID |
|
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gE |
Equid herpesvirus 1 |
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330789
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glycoprotein E |
Virulence factor |
MUTATION: A glycoprotein E mutant is attenuated in mice and hamsters [Ref1606:Patel and Heldens, 2005]. |
15993786
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gI |
Equid herpesvirus 1 |
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330788
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glycoprotein I |
Virulence factor |
MUTATION: A glycoprotein I mutant is attenuated in mice and hamsters [Ref1606:Patel and Heldens, 2005]. |
15993786
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TK |
Equid herpesvirus 1 Ab4 |
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59214
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thymidine kinase |
Virulence factor |
MUTATION: A thymidine kinase-deficient mutant (PR1) is attenuated in mice and foals [Ref7380:Slater et al., 1993]. |
8388018
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ORF71 |
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17221115
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17221116
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AAK61485.1 |
glycoprotein gp2 |
Virulence factor |
Irrespective of the reduced pathogenicity of the gene 71 mutant, infected mice were protected against a challenge with wild-type EHV-1. These findings highlight the potential of ED71 as a vaccine candidate. [Ref7474:Marshall et al., 1997] |
9143298
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gC |
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378556085
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378556086
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AFC17871.1 |
glycoprotein C |
Virulence factor |
Infection of mice with L11(delta)gC did not cause EHV-1-related disease, whereas mice infected with either RacL11 or R-L11(delta)gC exhibited massive bodyweight losses, high virus titers in the lungs, and viremia. [Ref7475:Osterrieder, 1999] |
10082388
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EUS8 |
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119926891
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119926892
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BAF43294.1 |
glycoprotein E |
Virulence factor |
Colostrum-deprived Thoroughbred foals inoculated intranasally (i.n.) or intramuscularly (i.m.) with DeltagE did not exhibit any clinical signs of respiratory disease except for a mild nasal discharge in 1 i.n. inoculated foal on Days 1 and 3 post-infection. In contrast, the intranasal inoculation of foals with the revertant of DeltagE resulted in biphasic pyrexia, mucopurulent nasal discharge and swelling of submandibular lymph nodes. [Ref7476:TSUJIMURA et al., 2009] |
19959893
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