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TK

Victor ID 4962
Gene Name TK
Sequence Strain (Species/Organism) Equid herpesvirus 1 Ab4
NCBI Protein GI 59214
Other Database IDs CDD:177537
GOA:P69185
InterPro: IPR001889
UniProtKB/UniProt: P69185
Taxonomy ID 10326
Gene Strand (Orientation) ?
Protein Name thymidine kinase
Protein Length 352
Protein Note thymidine kinase; Provisional
Protein Sequence 
>gi|59214|emb|CAA48144.1| thymidine kinase [Equid herpesvirus 1]
MAARVPSGEARRSASGAPVRRQVTIVRIYLDGVYGIGKSTTGRVMASAASGGSPTLYFPEPMAYWRTLFE
ADVISGIYDTQNRKQQGDLAADDAASITAHYQSRFTTPYLILHDHTFGLFGGDSLQRGTRPDLTVVFDRH
PVASAVCFPAARYLIGDMSMCALIAMVATLPREPQGGNIVVTTLNVDEHVRRLRTRARIGEQIDMKLIAT
LRNVYSMLANTSNFLRSGRVWRDGWGELPLSCETYKHRATQMDAFQERESPELSDTLFAMFKTPELLDDR
GVILEVHAWALDALMLKLRNLSVFCADLSGTPRQCAATVESLIPLMSSTLSDSESASSLERAARTFNAEM
GV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: A thymidine kinase-deficient mutant (PR1) is attenuated in mice and foals (Slater et al., 1993).
References
Slater et al., 1993: Slater JD, Gibson JS, Field HJ. Pathogenicity of a thymidine kinase-deficient mutant of equine herpesvirus 1 in mice and specific pathogen-free foals. The Journal of general virology. 1993; 74 ( Pt 5); 819-828. [PubMed: 8388018].