| Victors ID |
Gene Name |
Sequence Strain (Species/Organism) |
NCBI Gene ID |
NCBI Nucleotide GI |
NCBI Protein GI |
Locus Tag |
Genbank Accession |
Protein Accession |
Protein Name |
Molecule Role |
Molecule Role Annotation |
PMID |
|
|
cca |
Pseudomonas aeruginosa PAO1 |
877618
|
|
15595781
|
PA0584 |
|
NP_249275.1 |
multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase |
Virulence factor |
MUTATION: cca mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
modA |
Pseudomonas aeruginosa PAO1 |
877661
|
|
15597060
|
PA1863 |
|
NP_250554.1 |
molybdate-binding periplasmic protein ModA |
Virulence factor |
MUTATION: modA mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
metE |
Pseudomonas aeruginosa PAO1 |
877662
|
|
15597123
|
PA1927 |
|
NP_250617.1 |
5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase |
Virulence factor |
MUTATION: metE mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
algR |
Pseudomonas aeruginosa PAO1 |
877674
|
|
15600454
|
PA5261 |
|
NP_253948.1 |
alginate biosynthesis regulatory protein AlgR |
Virulence factor |
MUTATION: algR mutant is attenuated in mice [Ref6913:Lizewski et al., 2002]. |
12379685
|
|
|
PA5441 |
Pseudomonas aeruginosa |
877847
|
|
15600634
|
PA5441 |
|
NP_254128.1 |
hypothetical protein |
Virulence factor |
MUTATION: PA5441 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
toxA from Pseudomonas aeruginosa PAO1 |
Pseudomonas aeruginosa PAO1 |
877850
|
|
15596345
|
PA1148 |
|
NP_249839.1 |
exotoxin A |
Virulence factor |
TOXIN: toxA (exotoxin A) blocks protein synthesis by ADP ribosylation of elongation factor 2, thereby triggering cell death [Ref6914:Morlon-Guyot et al., 2009]. |
19380469
|
|
|
pilY1 from Pseudomonas aeruginosa PAO1 |
Pseudomonas aeruginosa PAO1 |
877859
|
|
15599750
|
PA4554 |
|
NP_253244.1 |
type 4 fimbrial biogenesis protein PilY1 |
Virulence factor |
MUTATION: pilY1 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
pilD from Pseudomonas aeruginosa PAO1 |
Pseudomonas aeruginosa PAO1 |
877861
|
|
15599724
|
PA4528 |
|
NP_253218.1 |
type 4 prepilin peptidase PilD |
Virulence factor |
MUTATION: pilD mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA5437 |
Pseudomonas aeruginosa |
877878
|
|
15600630
|
PA5437 |
|
NP_254124.1 |
putative transcriptional regulator |
Virulence factor |
MUTATION: PA5437 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA0151 |
Pseudomonas aeruginosa PAO1 |
877893
|
|
15595349
|
PA0151 |
|
NP_248841.1 |
putative TonB-dependent receptor |
Virulence factor |
MUTATION: PA0151 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
mucC |
Pseudomonas aeruginosa PAO1 |
877954
|
|
15595962
|
PA0765 |
|
NP_249456.1 |
positive regulator for alginate biosynthesis MucC |
Virulence factor |
MUTATION: mucC mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA5312 |
Pseudomonas aeruginosa |
877979
|
|
15600505
|
PA5312 |
|
NP_253999.1 |
putative aldehyde dehydrogenase |
Virulence factor |
MUTATION: PA5312 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
wbpX |
Pseudomonas aeruginosa PAO1 |
878014
|
|
15600642
|
PA5449 |
|
NP_254136.1 |
glycosyltransferase WbpX |
Virulence factor |
MUTATION: wbpX mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
hfq from Pseudomonas aeruginosa PAO1 |
Pseudomonas aeruginosa PAO1 |
878015
|
|
15600137
|
PA4944 |
|
NP_253631.1 |
RNA-binding protein Hfq |
Virulence factor |
MUTATION: When compared to PAO1 wild-type and the rpoS- mutant, the hfq- mutant decreased virulence in Galleria mellonella by a factor of 1 x 10(4) and 5 x 10(3), respectively. Likewise, when compared to wild-type, the PAO1hfq- mutant was significantly attenuated in virulence when administered intraperitoneally in mice [Ref6915:Sonnleitner et al., 2003]. |
14521880
|
|
|
pgm |
Pseudomonas aeruginosa |
878134
|
|
15600324
|
PA5131 |
|
NP_253818.1 |
phosphoglyceromutase |
Virulence factor |
MUTATION: pgm mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
pilI from Pseudomonas aeruginosa PAO1 |
Pseudomonas aeruginosa PAO1 |
878186
|
|
15595607
|
PA0410 |
|
NP_249101.1 |
twitching motility protein PilI |
Virulence factor |
MUTATION: pilI mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
purD from Pseudomonas aeruginosa PAO1 |
Pseudomonas aeruginosa PAO1 |
878236
|
|
15600048
|
PA4855 |
|
NP_253542.1 |
phosphoribosylamine--glycine ligase |
Virulence factor |
MUTATION: purD mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA5327 |
Pseudomonas aeruginosa |
878250
|
|
15600520
|
PA5327 |
|
NP_254014.1 |
putative oxidoreductase |
Virulence factor |
MUTATION: PA5327 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
exoT from Pseudomonas aeruginosa PAO1 |
Pseudomonas aeruginosa PAO1 |
878350
|
|
15595242
|
PA0044 |
|
NP_248734.1 |
exoenzyme T |
Virulence factor |
TOXIN: exoT interferes with Rho signal transduction pathways, which regulate actin organization, exocytosis, cell cycle progression, and phagocytosis [Ref6916:Krall et al., 2000]. |
10992524
|
|
|
PA0073 |
Pseudomonas aeruginosa PAO1 |
878396
|
|
15595271
|
PA0073 |
|
NP_248763.1 |
ABC transporter ATP-binding protein |
Virulence factor |
MUTATION: PA0073 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA0041 |
Pseudomonas aeruginosa PAO1 |
878601
|
|
15595239
|
PA0041 |
|
NP_248731.1 |
hemagglutinin |
Virulence factor |
MUTATION: PA0041 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
estA |
Pseudomonas aeruginosa PAO1 |
878826
|
|
15600305
|
PA5112 |
|
NP_253799.1 |
esterase EstA |
Virulence factor |
MUTATION: estA mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
rhlB |
Pseudomonas aeruginosa PAO1 |
878954
|
|
15598674
|
PA3478 |
|
NP_252168.1 |
rhamnosyltransferase chain B |
Virulence factor |
MUTATION: rhlB mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA1157 |
Pseudomonas aeruginosa PAO1 |
879028
|
|
15596354
|
PA1157 |
|
NP_249848.1 |
two-component response regulator |
Virulence factor |
MUTATION: PA1157 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
pgk |
Pseudomonas aeruginosa |
879198
|
|
15595749
|
PA0552 |
|
NP_249243.1 |
phosphoglycerate kinase |
Virulence factor |
MUTATION: pgk mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA1009 |
Pseudomonas aeruginosa PAO1 |
879264
|
|
15596206
|
PA1009 |
|
NP_249700.1 |
hypothetical protein |
Virulence factor |
MUTATION: PA1009 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
mucA |
Pseudomonas aeruginosa PAO1 |
879357
|
|
15595960
|
PA0763 |
|
NP_249454.1 |
anti-sigma factor MucA |
Virulence factor |
MUTATION: mucA mutant is attenuated in wounded alfalfa seedling infection model [Ref6917:Silo-Suh et al., 2002]. |
12426404
|
|
|
PA0082 |
Pseudomonas aeruginosa PAO1 |
879402
|
|
15595280
|
PA0082 |
|
NP_248772.1 |
hypothetical protein |
Virulence factor |
MUTATION: PA0082 mutant is attenuated in rats [Ref6918:Lehoux et al., 2002]. |
12023080
|
|
|
algC |
Pseudomonas aeruginosa PAO1 |
879406
|
|
15600515
|
PA5322 |
|
NP_254009.1 |
phosphomannomutase AlgC |
Virulence factor |
MUTATION: algC mutant is attenuated in neonatal mouse model of infection [Ref6919:Tang et al., 1996]. |
8557368
|
|
|
exoY from Pseudomonas aeruginosa PAO1 |
Pseudomonas aeruginosa PAO1 |
879421
|
|
15597387
|
PA2191 |
|
NP_250881.1 |
adenylate cyclase ExoY |
Virulence factor |
TOXIN: exoY is an adenylate cyclase that causes actin disruption in epithelial cells [Ref6920:Cowell et al., 2005]. |
16039071
|
|
|
clpV1 |
Pseudomonas aeruginosa PAO1 |
879553
|
|
15595288
|
PA0090 |
|
NP_248780.1 |
ClpV1 |
Virulence factor |
MUTATION: clpV1 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
mdoG |
Pseudomonas aeruginosa PAO1 |
879629
|
|
15600271
|
PA5078 |
|
NP_253765.1 |
glucan biosynthesis protein G |
Virulence factor |
MUTATION: mdoG mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
purL |
Pseudomonas aeruginosa PAO1 |
879752
|
|
15598958
|
PA3763 |
|
NP_252452.1 |
phosphoribosylformylglycinamidine synthase |
Virulence factor |
MUTATION: purL mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA4115 |
Pseudomonas aeruginosa |
879777
|
|
15599310
|
PA4115 |
|
NP_252804.1 |
hypothetical protein |
Virulence factor |
MUTATION: PA4115 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
narK2 |
Pseudomonas aeruginosa PAO1 |
879781
|
|
15599071
|
PA3876 |
|
NP_252565.1 |
nitrite extrusion protein 2 |
Virulence factor |
MUTATION: narK2 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA2972 |
Pseudomonas aeruginosa PAO1 |
879799
|
|
15598168
|
PA2972 |
|
NP_251662.1 |
Maf-like protein |
Virulence factor |
MUTATION: PA2972 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
exoS |
Pseudomonas aeruginosa PAO1 |
879837
|
|
15599036
|
PA3841 |
|
NP_252530.1 |
exoenzyme S |
Virulence factor |
MUTATION: exoS mutant is attenuated in a silk worm oral infection model [Ref6921:Okuda et al., 2010]. |
20805335
|
|
|
pepA |
Pseudomonas aeruginosa |
879865
|
|
15599026
|
PA3831 |
|
NP_252520.1 |
leucyl aminopeptidase |
Virulence factor |
MUTATION: pepA mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA3826 |
Pseudomonas aeruginosa |
879871
|
|
15599021
|
PA3826 |
|
NP_252515.1 |
hypothetical protein |
Virulence factor |
MUTATION: PA3826 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
wzz |
Pseudomonas aeruginosa PAO1 |
879922
|
|
15598356
|
PA3160 |
|
NP_251850.1 |
O-antigen chain length regulator |
Virulence factor |
MUTATION: wzz (wzz1) mutant is attenuated in mouse pneumonia model of infection [Ref6922:Kintz et al., 2008]. |
18065548
|
|
|
galU |
Pseudomonas aeruginosa PAO1 |
879968
|
|
15597219
|
PA2023 |
|
NP_250713.1 |
UTP-glucose-1-phosphate uridylyltransferase |
Virulence factor |
MUTATION: galU mutant is attenuated in corneal mouse model of infection [Ref6923:Priebe et al., 2004]. |
15213167
|
|
|
PA3498 |
Pseudomonas aeruginosa PAO1 |
880024
|
|
15598694
|
PA3498 |
|
NP_252188.1 |
oxidoreductase |
Virulence factor |
MUTATION: PA3498 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
purH |
Pseudomonas aeruginosa PAO1 |
880046
|
|
15600047
|
PA4854 |
|
NP_253541.1 |
bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase |
Virulence factor |
MUTATION: purH mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
nqrB |
Pseudomonas aeruginosa PAO1 |
880205
|
|
15598194
|
PA2998 |
|
NP_251688.1 |
Na(+)-translocating NADH-quinone reductase subunit B |
Virulence factor |
MUTATION: ngrB mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA3756 |
Pseudomonas aeruginosa PAO1 |
880314
|
|
15598951
|
PA3756 |
AE004091 |
NP_252445 |
hypothetical protein |
Virulence factor |
MUTATION: PA3756 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
thrC |
Pseudomonas aeruginosa PAO1 |
880336
|
|
15598930
|
PA3735 |
|
NP_252424.1 |
threonine synthase |
Virulence factor |
MUTATION: thrC mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA3001 |
Pseudomonas aeruginosa PAO1 |
880414
|
|
15598197
|
PA3001 |
|
NP_251691.1 |
glyceraldehyde-3-phosphate dehydrogenase |
Virulence factor |
MUTATION: PA3001 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
phzM |
Pseudomonas aeruginosa |
880514
|
|
15599404
|
PA4209 |
|
NP_252898.1 |
putative phenazine-specific methyltransferase |
Virulence factor |
MUTATION: phzM mutant is attenuated in mice [Ref6924:Lau et al., 2004]. |
15213173
|
|
|
PA4564 |
Pseudomonas aeruginosa |
880908
|
|
15599760
|
PA4564 |
|
NP_253254.1 |
hypothetical protein |
Virulence factor |
MUTATION: PA4564 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
algW |
Pseudomonas aeruginosa PAO1 |
880976
|
|
15599642
|
PA4446 |
|
NP_253136.1 |
AlgW protein |
Virulence factor |
MUTATION: algW mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA4491 |
Pseudomonas aeruginosa |
881054
|
|
15599687
|
PA4491 |
|
NP_253181.1 |
hypothetical protein |
Virulence factor |
MUTATION: PA4491 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA4489 |
Pseudomonas aeruginosa |
881072
|
|
15599685
|
PA4489 |
|
NP_253179.1 |
hypothetical protein |
Virulence factor |
MUTATION: PA4489 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA4488 |
Pseudomonas aeruginosa |
881219
|
|
15599684
|
PA4488 |
|
NP_253178.1 |
hypothetical protein |
Virulence factor |
MUTATION: PA4488 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
aprF |
Pseudomonas aeruginosa PAO1 |
881227
|
|
15596445
|
PA1248 |
|
NP_249939.1 |
alkaline protease secretion outer membrane protein AprF |
Virulence factor |
MUTATION: aprF mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
relA |
Pseudomonas aeruginosa PAO1 |
881299
|
|
15596131
|
PA0934 |
|
NP_249625.1 |
GTP pyrophosphokinase |
Virulence factor |
MUTATION: relA mutant is attenuated in D. melanogaster [Ref6925:Erickson et al., 2004]. |
15385461
|
|
|
PA4692 |
Pseudomonas aeruginosa |
881475
|
|
15599886
|
PA4692 |
|
NP_253380.1 |
putative sulfite oxidase subunit YedY |
Virulence factor |
MUTATION: PA4692 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
fur from Pseudomonas aeruginosa PAO1 |
Pseudomonas aeruginosa PAO1 |
881780
|
|
15599958
|
PA4764 |
|
NP_253452.1 |
ferric uptake regulation protein |
Virulence factor |
MUTATION: fur mutant is attenuated in mouse corneal scratch model [Ref6926:Preston et al., 1995]. |
7642283
|
|
|
lasR from Pseudomonas aeruginosa PAO1 |
Pseudomonas aeruginosa PAO1 |
881789
|
|
15596627
|
PA1430 |
|
NP_250121.1 |
transcriptional regulator LasR |
Virulence factor |
MUTATION: lasR mutant is attenuated in neonatal mouse model of infection [Ref6919:Tang et al., 1996]. |
8557368
|
|
|
phzS |
Pseudomonas aeruginosa |
881836
|
|
15599413
|
PA4217 |
|
NP_252907.1 |
hypothetical protein |
Virulence factor |
MUTATION: phzS mutant is attenuated in mice [Ref6924:Lau et al., 2004]. |
15213173
|
|
|
htpG |
Pseudomonas aeruginosa PAO1 |
881933
|
|
15596793
|
PA1596 |
|
NP_250287.1 |
heat shock protein 90 |
Virulence factor |
MUTATION: htpG mutant is attenuated in rats [Ref6918:Lehoux et al., 2002]. |
12023080
|
|
|
fliC from Pseudomonas aeruginosa PAO1 |
Pseudomonas aeruginosa PAO1 |
882052
|
|
15596289
|
PA1092 |
|
NP_249783.1 |
flagellin type B |
Virulence factor |
MUTATION: fliC mutant is attenuated in mice [Ref6927:Feldman et al., 1998]. |
9423837
|
|
|
algU |
Pseudomonas aeruginosa PAO1 |
882125
|
|
15595959
|
PA0762 |
|
NP_249453.1 |
RNA polymerase sigma factor AlgU |
Virulence factor |
MUTATION: algU mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA0158 |
Pseudomonas aeruginosa PAO1 |
882140
|
|
15595356
|
PA0158 |
|
NP_248848.1 |
resistance-nodulation-cell division family transporter |
Virulence factor |
MUTATION: PA0158 mutant is attenuated in rats [Ref6918:Lehoux et al., 2002]. |
12023080
|
|
|
PA4887 |
Pseudomonas aeruginosa |
882278
|
|
15600080
|
PA4887 |
|
NP_253574.1 |
major facilitator transporter |
Virulence factor |
MUTATION: PA4887 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
nuoD |
Pseudomonas aeruginosa PAO1 |
882346
|
|
15597835
|
PA2639 |
|
NP_251329.1 |
bifunctional NADH:ubiquinone oxidoreductase subunit C/D |
Virulence factor |
MUTATION: nuoD mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA3286 |
Pseudomonas aeruginosa PAO1 |
882449
|
|
15598482
|
PA3286 |
|
NP_251976.1 |
3-oxoacyl-(acyl carrier protein) synthase III |
Virulence factor |
MUTATION: PA3286 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
pyrF |
Pseudomonas aeruginosa PAO1 |
882585
|
|
15598072
|
PA2876 |
|
NP_251566.1 |
OMP decarboxylase; OMPDCase; OMPdecase |
Virulence factor |
MUTATION: pyrF mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA2895 |
Pseudomonas aeruginosa PAO1 |
882601
|
|
15598091
|
PA2895 |
|
NP_251585.1 |
hypothetical protein |
Virulence factor |
MUTATION: PA2895 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA3173 |
Pseudomonas aeruginosa PAO1 |
882633
|
|
15598369
|
PA3173 |
|
NP_251863.1 |
short chain dehydrogenase |
Virulence factor |
MUTATION: PA3173 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
pvdS |
Pseudomonas aeruginosa PAO1 |
882839
|
|
15597622
|
PA2426 |
|
NP_251116.1 |
extracytoplasmic-function sigma-70 factor |
Virulence factor |
MUTATION: pvdS mutant is attenuated in rabbit aortic endocarditis model [Ref6928:Xiong et al., 2000]. |
10720526
|
|
|
mvfR |
Pseudomonas aeruginosa UCBPP-PA14 |
4379987
|
|
116048931
|
PA14_51340 |
|
YP_792268.1 |
transcriptional regulator MvfR |
Virulence factor |
MUTATION: mvfR (pho34B12) mutant is attenuated in burned mouse model [Ref6979:Rahme et al., 1997]. |
9371831
|
|
|
exoU from Pseudomonas aeruginosa UCBPP-PA14 |
Pseudomonas aeruginosa UCBPP-PA14 |
4380009
|
|
116048914
|
PA14_51530 |
|
YP_792285.1 |
ExoU |
Virulence factor |
MUTATION: exoU mutant is avirulent in Dictyostelium discoideum, a genetically tractable eukaryotic organism [Ref6980:Pukatzki et al., 2002]. |
11867744
|
|
|
fliC from Pseudomonas aeruginosa UCBPP-PA14 |
Pseudomonas aeruginosa UCBPP-PA14 |
4380057
|
|
116049021
|
PA14_50290 |
|
YP_792177.1 |
flagellin type B |
Virulence factor |
MUTATION: fliC mutant is attenuated in mice [Ref6927:Feldman et al., 1998]. |
9423837
|
|
|
flhB from Pseudomonas aeruginosa UCBPP-PA14 |
Pseudomonas aeruginosa UCBPP-PA14 |
4380176
|
|
116049394
|
PA14_45720 |
|
YP_791803.1 |
flagellar biosynthesis protein FlhB |
Virulence factor |
MUTATION: flhB mutant is attenuated in Drosophila melanogaster and in mice [Ref6981:Kim et al., 2008]. |
18591226
|
|
|
PA14_38610 |
Pseudomonas aeruginosa UCBPP-PA14 |
4380287
|
|
116049953
|
PA14_38610 |
|
YP_791237.1 |
hypothetical protein |
Virulence factor |
MUTATION: PA14_38610 mutant is attenuated in Drosophila melanogaster and in mice [Ref6981:Kim et al., 2008]. |
18591226
|
|
|
PA14_37650 |
Pseudomonas aeruginosa UCBPP-PA14 |
4380319
|
|
116050024
|
PA14_37650 |
|
YP_791162.1 |
hypothetical protein |
Virulence factor |
MUTATION: PA14_37650 mutant is attenuated in Drosophila melanogaster and in mice [Ref6981:Kim et al., 2008]. |
18591226
|
|
|
pscJ |
Pseudomonas aeruginosa UCBPP-PA14 |
4380359
|
|
116049673
|
PA14_42270 |
|
YP_791522.1 |
pscJ type III export protein |
Virulence factor |
MUTATION: pscJ mutant is attenuated in Dictyostelium discoideum, a genetically tractable eukaryotic organism [Ref6980:Pukatzki et al., 2002]. |
11867744
|
|
|
PA14_33610 |
Pseudomonas aeruginosa UCBPP-PA14 |
4380463
|
|
116050342
|
PA14_33610 |
|
YP_790841.1 |
peptide synthase |
Virulence factor |
MUTATION: PA14_33610 (pvdI) mutant is attenuated in Drosophila melanogaster and in mice [Ref6981:Kim et al., 2008]. |
18591226
|
|
|
gacA |
Pseudomonas aeruginosa UCBPP-PA14 |
4380617
|
|
116050573
|
PA14_30650 |
|
YP_790608.1 |
response regulator GacA |
Virulence factor |
MUTATION: gacA mutant is attenuated in burned mouse model [Ref6979:Rahme et al., 1997]. |
9371831
|
|
|
PA14_41070 |
Pseudomonas aeruginosa UCBPP-PA14 |
4381036
|
|
116049764
|
PA14_41070 |
|
YP_791429.1 |
hypothetical protein |
Virulence factor |
MUTATION: kerV (PA14_41070) mutant is attenuated in mice [Ref6982:An et al., 2009]. |
19779606
|
|
|
prpR |
Pseudomonas aeruginosa UCBPP-PA14 |
4381387
|
|
116050154
|
PA14_36000 |
|
YP_791029.1 |
propionate catabolism operon regulator |
Virulence factor |
MUTATION: prpR mutant is attenuated in mice and Drosophila melanogaster [Ref6981:Kim et al., 2008]. |
18591226
|
|
|
toxA from Pseudomonas aeruginosa UCBPP-PA14 |
Pseudomonas aeruginosa UCBPP-PA14 |
4381678
|
|
116049080
|
PA14_49560 |
|
YP_792118.1 |
exotoxin A precursor |
Virulence factor |
MUTATION: toxA mutant is attenuated in burned mouse model [Ref6983:Rahme et al., 1995]. |
7604262
|
|
|
exoT from Pseudomonas aeruginosa UCBPP-PA14 |
Pseudomonas aeruginosa UCBPP-PA14 |
4381738
|
|
116053766
|
PA14_00560 |
|
YP_788201.1 |
exoenzyme T |
Virulence factor |
TOXIN: exoT interferes with Rho signal transduction pathways, which regulate actin organization, exocytosis, cell cycle progression, and phagocytosis [Ref6916:Krall et al., 2000]. |
10992524
|
|
|
pilF |
Pseudomonas aeruginosa |
4381875
|
|
116051830
|
PA14_14850 |
|
YP_789327.1 |
type 4 fimbrial biogenesis protein PilF |
Virulence factor |
MUTATION: pilF mutant is attenuated in Drosophila melanogaster and in mice [Ref6981:Kim et al., 2008]. |
18591226
|
|
|
PA14_35740 |
Pseudomonas aeruginosa UCBPP-PA14 |
4382109
|
|
116050177
|
PA14_35740 |
|
YP_791006.1 |
putative transposase |
Virulence factor |
MUTATION: tpnA mutant is attenuated in Drosophila melanogaster and in mice [Ref6981:Kim et al., 2008]. |
18591226
|
|
|
prpL |
Pseudomonas aeruginosa UCBPP-PA14 |
4382190
|
|
116052217
|
PA14_09900 |
|
YP_788939.1 |
Pvds-regulated endoprotease, lysyl class |
Virulence factor |
MUTATION: prpL mutant is attenuated in rats [Ref6984:Wilderman et al., 2001]. |
11500408
|
|
|
pilD from Pseudomonas aeruginosa UCBPP-PA14 |
Pseudomonas aeruginosa UCBPP-PA14 |
4382650
|
|
116052560
|
PA14_58770 |
|
YP_792875.1 |
type 4 prepilin peptidase PilD |
Virulence factor |
MUTATION: pilD mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
lasR from Pseudomonas aeruginosa UCBPP-PA14 |
Pseudomonas aeruginosa UCBPP-PA14 |
4382864
|
|
116049375
|
PA14_45960 |
|
YP_791822.1 |
transcriptional regulator LasR |
Virulence factor |
MUTATION: lasR mutant is avirulent in Dictyostelium discoideum [Ref6980:Pukatzki et al., 2002]. |
11867744
|
|
|
katA |
Pseudomonas aeruginosa UCBPP-PA14 |
4382943
|
|
116052272
|
PA14_09150 |
|
YP_788883.1 |
catalase |
Virulence factor |
MUTATION: katA mutant is attenuated in Drosophila melanogaster and in mice [Ref6985:Lee et al., 2005]. |
15972537
|
|
|
PA14_03120 |
Pseudomonas aeruginosa UCBPP-PA14 |
4383664
|
|
116053966
|
PA14_03120 |
|
YP_788404.1 |
putative transcriptional regulator |
Virulence factor |
MUTATION: PA14_03120 (hudR) mutant is attenuated in Drosophila melanogaster and in mice [Ref6981:Kim et al., 2008]. |
18591226
|
|
|
PA14_03530 |
Pseudomonas aeruginosa UCBPP-PA14 |
4383677
|
|
116053999
|
PA14_03530 |
|
YP_788441.1 |
transcriptional regulator |
Virulence factor |
MUTATION: PA14_03530 mutant is attenuated in Drosophila melanogaster and in mice [Ref6981:Kim et al., 2008]. |
18591226
|
|
|
PA14_04850 |
Pseudomonas aeruginosa UCBPP-PA14 |
4383758
|
|
116054099
|
PA14_04850 |
|
YP_788542.1 |
hypothetical protein |
Virulence factor |
MUTATION: PA14_04850 mutant is attenuated in Drosophila melanogaster and in mice [Ref6981:Kim et al., 2008]. |
18591226
|
|
|
pilI from Pseudomonas aeruginosa UCBPP-PA14 |
Pseudomonas aeruginosa UCBPP-PA14 |
4383800
|
|
116054141
|
PA14_05340 |
|
YP_788584.1 |
twitching motility protein PilI |
Virulence factor |
MUTATION: pilI mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
exoY from Pseudomonas aeruginosa UCBPP-PA14 |
Pseudomonas aeruginosa UCBPP-PA14 |
4384258
|
|
116054461
|
PA14_36345 |
|
YP_791058.1 |
adenylate cyclase ExoY |
Virulence factor |
TOXIN: exoY is an adenylate cyclase that causes actin disruption in epithelial cells [Ref6920:Cowell et al., 2005]. |
16039071
|
|
|
fabF1 |
Pseudomonas aeruginosa UCBPP-PA14 |
4384346
|
|
116050967
|
PA14_25690 |
|
YP_790208.1 |
3-oxoacyl-(acyl carrier protein) synthase II |
Virulence factor |
MUTATION: fabF1 mutant is attenuated in Drosophila melanogaster and in mice [Ref6981:Kim et al., 2008]. |
18591226
|
|
|
wspF |
Pseudomonas aeruginosa UCBPP-PA14 |
4384652
|
|
116051700
|
PA14_16480 |
|
YP_789461.1 |
chemotaxis-specific methylesterase |
Virulence factor |
MUTATION: wspF mutant is attenuated in Drosophila melanogaster [Ref6981:Kim et al., 2008]. |
18591226
|
|
|
dsbA |
Pseudomonas aeruginosa UCBPP-PA14 |
4385158
|
|
116053639
|
PA14_72450 |
|
YP_793966.1 |
thiol:disulfide interchange protein DsbA |
Virulence factor |
MUTATION: dsbA mutant is attenuated in Drosophila melanogaster and in mice [Ref6981:Kim et al., 2008]. |
18591226
|
|
|
plcH |
Pseudomonas aeruginosa UCBPP-PA14 |
4385302
|
|
116048767
|
PA14_53360 |
|
YP_792433.1 |
hemolytic phospholipase C precursor |
Virulence factor |
MUTATION: plcH mutant is attenuated in burned mouse model [Ref6983:Rahme et al., 1995]. |
7604262
|
|
|
pilY1 from Pseudomonas aeruginosa UCBPP-PA14 |
Pseudomonas aeruginosa UCBPP-PA14 |
4385727
|
|
116052698
|
PA14_60310 |
|
YP_793014.1 |
type 4 fimbrial biogenesis protein PilY1 |
Virulence factor |
MUTATION: pilY1 mutant is attenuated in rats [Ref6912:Potvin et al., 2003]. |
14641575
|
|
|
PA14_37260 |
Pseudomonas aeruginosa UCBPP-PA14 |
4385800
|
|
116050053
|
PA14_37260 |
|
YP_791133.1 |
putative porin |
Virulence factor |
MUTATION: opdO mutant is attenuated in Drosophila melanogaster and in mice [Ref6981:Kim et al., 2008]. |
18591226
|
|
|
exoT from Pseudomonas aeruginosa LESB58 |
Pseudomonas aeruginosa LESB58 |
7175181
|
|
218888792
|
PLES_00451 |
|
YP_002437656.1 |
exoenzyme T |
Virulence factor |
TOXIN: exoT interferes with Rho signal transduction pathways, which regulate actin organization, exocytosis, cell cycle progression, and phagocytosis [Ref6916:Krall et al., 2000]. |
10992524
|
|
|
exoY from Pseudomonas aeruginosa LESB58 |
Pseudomonas aeruginosa LESB58 |
7177486
|
|
218891856
|
PLES_31341 |
|
YP_002440723.1 |
adenylate cyclase ExoY |
Virulence factor |
TOXIN: exoY is an adenylate cyclase that causes actin disruption in epithelial cells [Ref6920:Cowell et al., 2005]. |
16039071
|
|
|
toxA from Pseudomonas aeruginosa LESB58 |
Pseudomonas aeruginosa LESB58 |
7178280
|
|
218892886
|
PLES_41711 |
|
YP_002441755.1 |
exotoxin A precursor |
Virulence factor |
TOXIN: toxA (exotoxin A) blocks protein synthesis by ADP ribosylation of elongation factor 2, thereby triggering cell death [Ref6914:Morlon-Guyot et al., 2009]. |
19380469
|
|
|
fliC from Pseudomonas aeruginosa LESB58 |
Pseudomonas aeruginosa LESB58 |
7178326
|
|
218892944
|
PLES_42291 |
|
YP_002441813.1 |
flagellin type B |
Virulence factor |
MUTATION: fliC mutant is attenuated in mice [Ref6927:Feldman et al., 1998]. |
9423837
|
|
|
LPS |
Pseudomonas aeruginosa |
|
|
|
|
|
|
|
Virulence factor |
MUTATION: an LPS mutant was nonvirulent in a burned mouse model of infection [Ref7283:Cryz et al., 1984]. |
6425224
|
