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exoS

Victor ID 4237
Gene Name exoS
Sequence Strain (Species/Organism) Pseudomonas aeruginosa PAO1
NCBI Gene ID 879837
NCBI Protein GI 15599036
Locus Tag PA3841
Protein Accession NP_252530.1
Other Database IDs UniProtKB-ID: Q51449_PSEAE
UniRef100: UniRef100_B7UVS6
UniRef90: UniRef90_B7UVS6
UniRef50: UniRef50_B7UVS6
UniParc: UPI00000D4767
EMBL: L27629
EMBL: AE004091
EMBL: AY029239
EMBL: AY029247
EMBL: AY029241
EMBL: AY029249
EMBL: AY029240
EMBL: AY029250
EMBL: AY029244
EMBL-CDS: AAA66491.1
EMBL-CDS: AAG07228.1
EMBL-CDS: AAK38417.1
EMBL-CDS: AAK38419.1
EMBL-CDS: AAK38420.1
EMBL-CDS: AAK38436.1
EMBL-CDS: AAK38478.1
EMBL-CDS: AAK38479.1
EMBL-CDS: AAK39624.1
RefSeq_NT: NC_002516.2
HSSP: Q51451
GenomeReview
Taxonomy ID 208964
Gene Starting Position 4303140
Gene Ending Position 4304501
Gene Strand (Orientation) -
Protein Name exoenzyme S
DNA Sequence 
>gi|110645304:4303140-4304501 Pseudomonas aeruginosa PAO1 chromosome, complete genome
GTCAGGCCAGATCAAGGCCGCGCATCCTCAGGCGTACATCCTGTTCCTGGACCTCGCCTGAACGTTCCGG
TTTGCTTGCCAGGTCGAGAGCATCGAGCAGTCCCTGGCTATGGCCACTCTGCTCCCCCAGGGCCGCCTCT
TCGAGGACCCGGCGGGTCACTCCCTGCTCATCGCTGGCGCTCAGCAGCACGCGCATGTCGGTCTCTTTGT
TATAGAGAATCTCTTTTTCATTCTTGTAGTTCGATATCCCGCTGACATCGATTCCGGACCTGCCGAACAC
GGTGGATATCGTGCCCTGCCCGAAGCTCCTCGCGACACCGGGGTTCAGGGAGGTGGAGAGATAGCCGTCG
TCGTGGCCAACCTTGCCCTCTTCCACGGCGTTGAAGGCATCCCCGCCACGGGTGCCACGGAAAGTCTTCA
CTACCTGTTCAGCCTGTCCGCTCTTCTCGAAGGCCGCGGACATACCTTGGTCGATCAGCTTTTGTCCCGC
ATCCAGCTCCTGCCCCTGACGCAGAGCGCGATTCAGGTCCGCGTAGTGAATGCCGGTGTAGAGACCAAGC
GCCATCACTTCGGCGTCACTGTGGATGCCACCAGGCTGTCTGCCCAGGTACTTTTCCGCATCCGCCCCGA
ACCGCTTCACCAGGCCATCCGCCAGCGCCTTGTCGGCCGATACTCTGCTGACCTCGCTCTCTACCGCTTG
GCGCAACAGTGCGACCTCGCTCATTACCTGATGCAACTGGTCGGTGATTTCGCGCCGCAGTTCCGGGCTT
GCGTCGAGCACCAGTTGACTCGCGGCACCGCCGGTGGTGCCCCACTGCTGCAGCGCGATCCCGCCGATGC
TCCGTTCGAGCAGGCGGCCAGCCTGGATACGGGACTCCTCGACCTGGCTGCCGGCACGAATGCCGGCCAA
GGCGGTGCTCAGCGAACGCAGCGCCCCATCTCCGCTGGCCAGGCGGGAGTGCTCCCGGGCCAGTCCTTCC
GGTGTCAGGGTCGCCAGCTCGCTCGCCTTGTCGAGTCCCTTCAAGGTCATGGGCAATGCCTGCTGCAGCA
CCATCTGCTTGAACACGACGGCCGAGGACATGACCGCAGGCTGCGCGTCCTGACTGGGCTGCGGGCCGGT
GCGGGCGTGGGAGCCCAACAGCTTGCCCAGCCAGTCCATGATCGCCACGAAGGGACGCACGAGTGCCGCA
CCCAAGCGAGCGAGCAGCCCCTCACCCTTCGGCGCGTCCTGGCGCTGGGCCAACTGCTGCGCTTCACTGG
GGGTGGCGACCTGGCGGGCCTCAATCTGTCCCAAACGCCCACTGGCGGCCTGGTGCAATTCGACGGCGAA
AGACGGACTCTGCTGAAGCGATTGAATATGCA
Protein Sequence 
>gi|15599036|ref|NP_252530.1| exoenzyme S [Pseudomonas aeruginosa PAO1] MHIQSLQQSPSFAVELHQAASGRLGQIEARQVATPSEAQQLAQRQDAPKGEGLLARLGAALVRPFVAIMDWLGKLLGSHARTGPQPSQDAQPAVMSSAVVFKQMVLQQALPMTLKGLDKASELATLTPEGLAREHSRLASGDGALRSLSTALAGIRAGSQVEESRIQAGRLLERSIGGIALQQWGTTGGAASQLVLDASPELRREITDQLHQVMSEVALLRQAVESEVSRVSADKALADGLVKRFGADAEKYLGRQPGGIHSDAEVMALGLYTGIHYADLNRALRQGQELDAGQKLIDQGMSAAFEKSGQAEQVVKTFRGTRGGDAFNAVEEGKVGHDDGYLSTSLNPGVARSFGQGTISTVFGRSGIDVSGISNYKNEKEILYNKETDMRVLLSASDEQGVTRRVLEEAALGEQSGHSQGLLDALDLASKPERSGEVQEQDVRLRMRGLDLA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: exoS mutant is attenuated in a silk worm oral infection model (Okuda et al., 2010).
COG COG5585T, under T: Signal transduction mechanisms
References
Okuda et al., 2010: Okuda J, Hayashi N, Okamoto M, Sawada S, Minagawa S, Yano Y, Gotoh N. Translocation of Pseudomonas aeruginosa from the intestinal tract is mediated by the binding of ExoS to an Na,K-ATPase regulator, FXYD3. Infection and immunity. 2010; 78(11); 4511-4522. [PubMed: 20805335].