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exoU from Pseudomonas aeruginosa UCBPP-PA14

Victor ID 4400
Gene Name exoU from Pseudomonas aeruginosa UCBPP-PA14
Sequence Strain (Species/Organism) Pseudomonas aeruginosa UCBPP-PA14
NCBI Gene ID 4380009
NCBI Protein GI 116048914
Locus Tag PA14_51530
Protein Accession YP_792285.1
Other Database IDs UniProtKB-ID: Q02IF1_PSEAB
UniRef100: UniRef100_Q02IF1
UniRef90: UniRef90_Q02IF1
UniRef50: UniRef50_Q02IF1
UniParc: UPI00000BC38D
EMBL: CP000438
EMBL-CDS: ABJ10150.1
RefSeq_NT: NC_008463.1
GenomeReviews: CP000438_GR
KEGG: pau:PA14_51530
eggNOG: COG1752
HOGENOM: HBG640796
ProtClustDB: CLSK2487124
BioCyc: PAER208963:PA14_51530-MONOMER
Taxonomy ID 208963
Gene Starting Position 4580956
Gene Ending Position 4583019
Gene Strand (Orientation) -
Protein Name ExoU
DNA Sequence 
>gi|116048575:4580956-4583019 Pseudomonas aeruginosa UCBPP-PA14, complete genome
ATCATGTGAACTCCTTATTCCGCCAAGCCTTAGCCATCTCAACGGTAGTCGAACTCAAGGGTTTGCCGAA
ACGCAGGAAGCCTCGTGCCGAGTAGTTGTCGACGATATCGTTCAGCGCTTGATTGATTTCCGCCGGACTG
GTGGCATGCCGTAGCTGCTCCTCCGCCCGACGTAACAGAGCTACGTTGGAATCCGGCTGGCCAGGGCGAT
ACAGAGAGGGGAAGATAACTTCCTTACGAATGTTCTCGGCAATAACCGCCACTTTGCGGCGCTGCGCCTC
TGCTAACGCAGCGGCGAGCACCGGCGACTGCACCGTCTGCCCGCGCATGGCATCGAGTAACTGCTGATGA
TCAACGTTATCAGCATGGTTCAACTCAGCTGCCAACCATGCTAGGCGTTCCGGAGTATCTGCCAGCGCAT
CGAGTCGCTGAAGAGCGGAGCGCATAGCCTCGTCCAACTTGAGCCTACCCGCCAAGCCATTGGCGCTAAC
GATAGCGACAGTCAGCTCGGTGAACGCATCCCGCGCCTTCTGGCGAAAAGCCACCGCCCCGTCTGTGATC
TCCGGGTTCTGTTGAGCAACACTGGTGAGCATACTGTCATCAAGTGCCAGCAGCGCCTCGTCGAGAGAAG
CGAAGGTATGACGCTCTGAAGCCTGAAGACGTTTCTCCAGATGTTCACCGACTCGCTCCTGGAGGCGCTC
CTGAAGATGCGCCTTGATCTCGTCCGGCATGGTGAAGTTCAAGGTGCCACCGAGCATGCCACTGAAATCA
CCGCGCTCGCTCTTCAACGGCACCACAACGGTTTGCTCGCGCAATTCCTCCAGGCCCTCGAGCTGCAGCA
TTTCGCGCGCCTGCAGGGCAGGCACCCCGACGACCCAGCCCTTGAGCGCGCCGCCCCTAGTACCTCGGTC
GGGCGCTACCTCCCCAGCTTCGCCCTCGAACTCAAGGATCAGGTTGTCGTTGCGCCGCAGTGGCCCGCTG
TCAAAATTCTTGTCGATCATCTCAGGGACCGGCACGTTAATCATCACCCCGCCATCCTGGAATTCTGTCC
ACTCTACGCCGGCCTGGTACGGCTGATCACTCAAGCTGACCTTCTGGAACACTCCTGGGAAGGAACCGGA
GATATGTGCCGCCTGGGCGACCTCCAGATCCGGTGTGTGGCTGGCATTGAACACCACTAATTGCGGACGC
CCCTCGAACATGGCCGTACCTGTGATGTTCAGCGTCTTAATCTGGGGAATGTAAGCACTCAACCGATCTA
GATCGCCAAAGGTGACTCCGGAGCCGGACTGCAATCTGCTGGCGATGGCGGCAACGGTCGGCTGGCGTGC
AACCTCTGGATGCGTAGCGATCTGTCCGAGCACGGCCTTGCGTGTCTCGTCGCGCAATAGGCGTTCTAGG
GGCTCAGCCCGCGAATCTATGCGTGGGAGTACATTGAGCAGCAACTCAGAGAAGCCGCCGATCTTGTTGC
CCAAGCCCTTTTTCAGCGATGCGCCGATCTCGCTGCTAATGTGTTGGAACAGCTTCAGCTTCTTGTTCGA
GCTGTCGAGCAGCGAAATAAGATCCATCTTGTCGGAAAGGGTCTTGAACGCCGCCGGGCTCATACCTGAG
GCCAAAAGGGCGGCGGTGATGCCGCCAGCGGACGAACCGGACATGCTGCGGATGCCATCGAGCATGCCTT
TCTCTTCTAGCGCCAGCATTGCTCCCGGGTATGCCGCACCTTTGGCACCACCGCCGCTTAGGACCAGACT
GGTCAATGGTGGCCGACTGAGCTGTAGCTCGGTGACTCCGTTCTCAAACTGGCGCAGAGTGATCTGCCGC
GGCCCTGCCGAGTCAGTCAGAGTACGGGACTCCCCTTGCCCTTGGGGACTGCTGAAACGCACGTCGCTAA
CGCTTTCCGGCAACTTCCCGGAAAGTATTCCCGGCGTGCTCTTTAGGGCAACCCCGAGACCTTGCCCTGA
AGGTTCCTGACGCAAGCTGGCGGACTTATGCGCTGCCTGCGACGGGGTTTCGACAGGCTCCTGATTCAGC
GAGGAGGCAGTAGCCCCCAACGATTGGATATGCA
Protein Sequence 
>gi|116048914|ref|YP_792285.1| ExoU [Pseudomonas aeruginosa UCBPP-PA14] MHIQSLGATASSLNQEPVETPSQAAHKSASLRQEPSGQGLGVALKSTPGILSGKLPESVSDVRFSSPQGQGESRTLTDSAGPRQITLRQFENGVTELQLSRPPLTSLVLSGGGAKGAAYPGAMLALEEKGMLDGIRSMSGSSAGGITAALLASGMSPAAFKTLSDKMDLISLLDSSNKKLKLFQHISSEIGASLKKGLGNKIGGFSELLLNVLPRIDSRAEPLERLLRDETRKAVLGQIATHPEVARQPTVAAIASRLQSGSGVTFGDLDRLSAYIPQIKTLNITGTAMFEGRPQLVVFNASHTPDLEVAQAAHISGSFPGVFQKVSLSDQPYQAGVEWTEFQDGGVMINVPVPEMIDKNFDSGPLRRNDNLILEFEGEAGEVAPDRGTRGGALKGWVVGVPALQAREMLQLEGLEELREQTVVVPLKSERGDFSGMLGGTLNFTMPDEIKAHLQERLQERVGEHLEKRLQASERHTFASLDEALLALDDSMLTSVAQQNPEITDGAVAFRQKARDAFTELTVAIVSANGLAGRLKLDEAMRSALQRLDALADTPERLAWLAAELNHADNVDHQQLLDAMRGQTVQSPVLAAALAEAQRRKVAVIAENIRKEVIFPSLYRPGQPDSNVALLRRAEEQLRHATSPAEINQALNDIVDNYSARGFLRFGKPLSSTTVEMAKAWRNKEFT
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: exoU mutant is avirulent in Dictyostelium discoideum, a genetically tractable eukaryotic organism (Pukatzki et al., 2002).
COG COG1752R, under R: General function prediction only
References
Pukatzki et al., 2002: Pukatzki S, Kessin RH, Mekalanos JJ. The human pathogen Pseudomonas aeruginosa utilizes conserved virulence pathways to infect the social amoeba Dictyostelium discoideum. Proceedings of the National Academy of Sciences of the United States of America. 2002; 99(5); 3159-3164. [PubMed: 11867744].