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aprF

Victor ID 4254
Gene Name aprF
Sequence Strain (Species/Organism) Pseudomonas aeruginosa PAO1
NCBI Gene ID 881227
NCBI Protein GI 15596445
Locus Tag PA1248
Protein Accession NP_249939.1
Other Database IDs UniProtKB-ID: APRF_PSEAE
UniRef100: UniRef100_Q03027
UniRef90: UniRef90_Q03027
UniRef50: UniRef50_Q03027
UniParc: UPI0000125CB7
EMBL: X64558
EMBL: AE004091
EMBL-CDS: CAA45857.1
EMBL-CDS: AAG04637.1
RefSeq_NT: NC_002516.2
GenomeReviews: AE004091_GR
KEGG: pae:PA1248
PseudoCAP: PA1248
HOGENOM: HBG647495
OMA: SESEYNY
ProtClustDB: CLSK2392922
BioCyc: PAER208964:PA1248-MONOMER
Taxonomy ID 208964
Gene Starting Position 1353826
Gene Ending Position 1355271
Gene Strand (Orientation) +
Protein Name alkaline protease secretion outer membrane protein AprF
DNA Sequence 
>gi|110645304:1353826-1355271 Pseudomonas aeruginosa PAO1 chromosome, complete genome
GATGACCATGCGCCGCCTGATGACCTGGCTGTTCGGCGCCTTCCTGTTGCTGCTGCGCGAGGACGCCTTC
GCCCTCGGCCTGCTGGACGGCTATCACCTGGCCCTGGAGAACGACCCGCAGTTCCAGGCCGCGATCCAGG
AGCACGAGGCCGGCAGGCAATACCGTGCGCTCGGCCGCGCGGCGCTGCTGCCGCGCCTGGTGTACAGCTA
CAACCGTGGGCGCAGCTGGTCCGATGTGACCCAGACCACCACCCGCGGCGATTTCAAGGAAGACCGCGAC
TACGACAGCTACGTCTCCACCCTCAGCCTGCAACAGCCGTTGTTCGACTACGAGGCCTTCAGCCGCTACC
GCAAGGGCGTGGCCCAGGCGCTGCTGTCCGACGAGCGCTTCCGCAGCCAGAGCCAGGAACTGCTGGTCCG
GGTCCTGGAAGCCTATACCGGCGCGCTGCTGGCCCAGGACCAGATCGAACTGGCGCGGGCGCAGAAACGC
TCCTACCGCGAGCAGTTCCAGCTCAACCAGCGCCAGTTCGAGCGCGGCAACGGCACCCGCACCGACACCC
TGGAGACCCAGGCCCGCTTCAACCTGGCCCAGGCCCAGGAAATCGAGGCGCGGGACAGCCAGGATGCCGC
CCTGCGCGAACTGGAGCGGCTGGTCGGGGCGCCGCTGGAGATCGCCGACCTGGCGCCGCTCGGCGAACGC
TTCCAGGTGCGCCCGCTGAGCCCCGCCAGCTACACCGCCTGGCGCGACCTGGCGCTGGCCGAGAATCCCG
AGCTGGCCTCGCTGCGCCACGCGGTGGACGTGGCCCGCTACGAGGTCGAGCAGAACCGCGCCGACTTCCT
GCCGCGCCTGGGCCTGTACGCCAGCACCGGCAAGTCCAAGTCCGGTTCGGAGAACACCTACAACCAGCGC
TACGAGACCGACAGCGTCGGCATCCAGTTGAGCGTTCCGCTGTTCTCCGGCGGCGAGACCCTGGCGGCGA
CGCGCCAGGCCACGCATCGCATGGAGAAGAGCCATTACGACCTGGACGACAAGGTCCGCGAGACCCTCAA
CCAGGTGCGCAAGATGTACAACCAGAGCAGCAGCAGCGCGGCGAAGATCCGCGCCTACGAGATGACCGTG
GATTCGGCGCGGACGCTGGTGATGGCCACGCGCAAGAGCATCGCCGCCGGGGTGCGGGTCAACCTCGACC
TGCTGAACGCCGAGCAGGCGCTGTACAGCGCGATGAATGAGCTGTCCAAGGCCAAGTACGACTACCTCAC
GGCCTGGGCACGCCTGCGTTTCTACGCCGGGGTGCTGGACGAAGCCGACCTGGAACTGGTGGCGGCGAAC
TTCGTTTCCGGCGAGACGCCGGCGCGCCGCCGCGACTGCGCGACGACGGATTGCCCGGCGCCGCTGCACA
CCCTGTCGAAGACCGATACGGAGGAAAACCGGAGCGCGCTCAATTG
Protein Sequence 
>gi|15596445|ref|NP_249939.1| alkaline protease secretion outer membrane protein AprF [Pseudomonas aeruginosa PAO1] MTMRRLMTWLFGAFLLLLREDAFALGLLDGYHLALENDPQFQAAIQEHEAGRQYRALGRAALLPRLVYSYNRGRSWSDVTQTTTRGDFKEDRDYDSYVSTLSLQQPLFDYEAFSRYRKGVAQALLSDERFRSQSQELLVRVLEAYTGALLAQDQIELARAQKRSYREQFQLNQRQFERGNGTRTDTLETQARFNLAQAQEIEARDSQDAALRELERLVGAPLEIADLAPLGERFQVRPLSPASYTAWRDLALAENPELASLRHAVDVARYEVEQNRADFLPRLGLYASTGKSKSGSENTYNQRYETDSVGIQLSVPLFSGGETLAATRQATHRMEKSHYDLDDKVRETLNQVRKMYNQSSSSAAKIRAYEMTVDSARTLVMATRKSIAAGVRVNLDLLNAEQALYSAMNELSKAKYDYLTAWARLRFYAGVLDEADLELVAANFVSGETPARRRDCATTDCPAPLHTLSKTDTEENRSALN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aprF mutant is attenuated in rats (Potvin et al., 2003).
COG COG1538MU, under M: Cell wall/membrane/envelope biogenesis; U: Intracellular trafficking, secretion, and vesicular transport
References
Potvin et al., 2003: Potvin E, Lehoux DE, Kukavica-Ibrulj I, Richard KL, Sanschagrin F, Lau GW, Levesque RC. In vivo functional genomics of Pseudomonas aeruginosa for high-throughput screening of new virulence factors and antibacterial targets. Environmental microbiology. 2003; 5(12); 1294-1308. [PubMed: 14641575].