Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

purH

Victor ID 4243
Gene Name purH
Sequence Strain (Species/Organism) Pseudomonas aeruginosa PAO1
NCBI Gene ID 880046
NCBI Protein GI 15600047
Locus Tag PA4854
Protein Accession NP_253541.1
Other Database IDs UniProtKB-ID: PUR9_PSEAE
UniRef100: UniRef100_B7V1R6
UniRef90: UniRef90_A6VCW0
UniRef50: UniRef50_B7V1R6
UniParc: UPI00000C5E3D
EMBL: AE004091
EMBL-CDS: AAG08239.1
RefSeq_NT: NC_002516.2
GenomeReviews: AE004091_GR
KEGG: pae:PA4854
PseudoCAP: PA4854
HOGENOM: HBG498048
OMA: ASDGFFP
ProtClustDB: PRK00881
BioCyc: PAER208964:PA4854-MONOMER
Taxonomy ID 208964
Gene Starting Position 5449045
Gene Ending Position 5450652
Gene Strand (Orientation) +
Protein Name bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
DNA Sequence 
>gi|110645304:5449045-5450652 Pseudomonas aeruginosa PAO1 chromosome, complete genome
AATGACCGACCAAACCACCCGCCTGCCCATCCGCCGCGCGCTGATCAGCGTTTCCGACAAGACCGGCGTC
GTCGACTTCGCCCGTGAGCTGGTCGCCCTCGGCGTGGAAATCCTTTCCACCGGCGGCACCTACAAGCTGC
TCCGGGACAACGGCATCTCTGCCGTGGAAGTGGCCGACTACACCGGCTTCCCGGAAATGATGGACGGTCG
GGTGAAGACCCTGCACCCGAAGGTGCATGGCGGTATCCTCGGTCGCCGCGACCTGGACGGCGCGGTCATG
GAGCAGCACGGCATCAAGCCGATCGACCTGGTGGCGGTCAACCTGTATCCCTTCGAGGCCACGGTGGCCA
GGCCCGACTGCGACCTGCCTACCGCCATCGAGAACATCGATATCGGCGGGCCGACCATGGTCCGTTCGGC
GGCGAAGAACCACAAGGATGTCGCCATCGTGGTCAATGCCGGCGACTACGCCGCCGTGATCGAATCCCTC
AAGGCCGGCGGCCTGACCTACGCCCAGCGTTTCGACCTGGCCCTCAAGGCGTTCGAGCACACCTCCGCCT
ACGACGGCATGATCGCCAACTACCTGGGTACCATCGACCAGACCCGCGATACCCTAGGCACCGCCGACCG
CGGCGCCTTCCCGCGCACCTTCAACAGTCAGTTCGTCAAGGCCCAGGAAATGCGCTACGGCGAGAACCCG
CACCAGAGCGCGGCGTTCTACGTCGAGGCGAAGAAGGGCGAGGCCAGCGTCTCCACCGCCATCCAGTTGC
AGGGCAAGGAACTGTCGTTCAACAACGTCGCCGACACCGACGCCGCCCTGGAATGCGTGAAGAGCTTCCT
CAAGCCGGCCTGCGTGATCGTCAAGCATGCCAACCCCTGCGGCGTCGCCGTGGTGCCGGAAGACGAAGGC
GGCATCCGCAAGGCCTACGACCTGGCCTACGCCACCGATAGCGAATCGGCGTTCGGCGGCATCATCGCCT
TCAACCGCGAGCTGGACGGCGAAACCGCCAAGGCCATCGTCGAGCGCCAGTTCGTCGAGGTGATCATCGC
GCCGAAGATTTCCGCCGCCGCCCGCGAGGTGGTCGCCGCCAAGGCCAACGTACGCCTGCTCGAATGCGGC
GAATGGCCAGCCGAGCGCGCCCCGGGCTGGGACTTCAAGCGGGTCAACGGCGGCCTGCTGGTACAGAGCC
GCGACATCGGCATGATCAAGGCCGAGGACCTGAAGATCGTCACTCGCCGCGCGCCCACCGAGCAGGAGAT
CCACGACCTGATCTTCGCCTGGAAGGTGGCCAAGTTCGTCAAGTCCAACGCCATCGTCTACGCCAGGAAC
CGCCAGACCGTCGGCGTCGGCGCCGGCCAGATGAGCCGGGTCAACTCCGCACGGATCGCCGCGATCAAGG
CCGAGCACGCCGGCCTGGAAGTGAAAGGCGCGGTGATGGCTTCCGACGCCTTCTTCCCGTTCCGCGACGG
CATCGACAACGCGGCCAAGGCCGGCATCACCGCGGTGATCCAGCCGGGCGGCTCGATGCGCGACAACGAA
GTGATCGCGGCGGCCGACGAGGCGGATATCGCGATGGTGTTCACTGGCATGCGCCATTTCCGCCATTG
Protein Sequence 
>gi|15600047|ref|NP_253541.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Pseudomonas aeruginosa PAO1] MTDQTTRLPIRRALISVSDKTGVVDFARELVALGVEILSTGGTYKLLRDNGISAVEVADYTGFPEMMDGRVKTLHPKVHGGILGRRDLDGAVMEQHGIKPIDLVAVNLYPFEATVARPDCDLPTAIENIDIGGPTMVRSAAKNHKDVAIVVNAGDYAAVIESLKAGGLTYAQRFDLALKAFEHTSAYDGMIANYLGTIDQTRDTLGTADRGAFPRTFNSQFVKAQEMRYGENPHQSAAFYVEAKKGEASVSTAIQLQGKELSFNNVADTDAALECVKSFLKPACVIVKHANPCGVAVVPEDEGGIRKAYDLAYATDSESAFGGIIAFNRELDGETAKAIVERQFVEVIIAPKISAAAREVVAAKANVRLLECGEWPAERAPGWDFKRVNGGLLVQSRDIGMIKAEDLKIVTRRAPTEQEIHDLIFAWKVAKFVKSNAIVYARNRQTVGVGAGQMSRVNSARIAAIKAEHAGLEVKGAVMASDAFFPFRDGIDNAAKAGITAVIQPGGSMRDNEVIAAADEADIAMVFTGMRHFRH
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: purH mutant is attenuated in rats (Potvin et al., 2003).
COG COG0138F, under F: Nucleotide transport and metabolism
References
Potvin et al., 2003: Potvin E, Lehoux DE, Kukavica-Ibrulj I, Richard KL, Sanschagrin F, Lau GW, Levesque RC. In vivo functional genomics of Pseudomonas aeruginosa for high-throughput screening of new virulence factors and antibacterial targets. Environmental microbiology. 2003; 5(12); 1294-1308. [PubMed: 14641575].