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toxA from Pseudomonas aeruginosa UCBPP-PA14

Victor ID 4410
Gene Name toxA from Pseudomonas aeruginosa UCBPP-PA14
Sequence Strain (Species/Organism) Pseudomonas aeruginosa UCBPP-PA14
NCBI Gene ID 4381678
NCBI Protein GI 116049080
Locus Tag PA14_49560
Protein Accession YP_792118.1
Other Database IDs UniProtKB-ID: Q02IW8_PSEAB
UniRef100: UniRef100_Q02IW8
UniRef90: UniRef90_P11439
UniRef50: UniRef50_P11439
UniParc: UPI000045D0C3
EMBL: CP000438
EMBL-CDS: ABJ10316.1
RefSeq_NT: NC_008463.1
GenomeReviews: CP000438_GR
KEGG: pau:PA14_49560
NMPDR: fig|208963.3.peg.2771
HOGENOM: HBG639690
OMA: AHESNEM
ProtClustDB: CLSK545809
BioCyc: PAER208963:PA14_49560-MONOMER
Taxonomy ID 208963
Gene Starting Position 4407440
Gene Ending Position 4409347
Gene Strand (Orientation) +
Protein Name exotoxin A precursor
DNA Sequence 
>gi|116048575:4407440-4409347 Pseudomonas aeruginosa UCBPP-PA14, complete genome
GATGCACCTGATACCCCATTGGATCCCCCTGGTCGCCAGCCTCGGCCTGCTCGCCGGCGGCTCGTTCGCG
TCCGCCGCCGAGGAAGCCTTCGACCTCTGGAACGAATGCGCCAAGGCCTGCGTGCTCGACCTCAAGGACG
GCGTGCGTTCCAGCCGCATGAGCGTCGACCCGGCCATCGCCGACACCAACGGCCAGGGCGTGCTGCACTA
CTCCATGGTCCTGGAGGGCGGCAACGACGCGCTCAAGCTGGCCATCGACAACGCCCTCAGCATCACCAGC
GACGGCCTGACCATCCGCCTCGAAGGCGGCGTCGAGCCGAACAAGCCGGTGCGCTACAGCTACACGCGCC
AGGCGCGCGGCAGTTGGTCGCTGAACTGGCTGGTACCGATCGGCCACGAGAAGCCCTCGAACATCAAGGT
GTTCATCCACGAACTGAACGCCGGTAACCAGCTCAGCCACATGTCGCCGATCTACACCATCGAGATGGGC
GACGAGTTGCTGGCGAAGCTGGCGCGCGATGCCACCTTCTTCGTCAGGGCGCACGAGAGCAACGAGATGC
AGCCGACGCTCGCCATCAGCCATGCCGGGGTCAGCGTGGTCATGGCCCAGACCCAGCCGCGCCGGGAAAA
GCGCTGGAGCGAATGGGCCAGCGGCAAGGTGTTGTGCCTGCTCGACCCGCTGGACGGGGTCTACAACTAC
CTCGCCCAGCAACGCTGCAACCTCGACGATACCTGGGAAGGCAAGATCTACCGGGTGCTCGCCGGCAACC
CGGCGAAGCATGACCTGGACATCAAGCCCACGGTCATCAGTCATCGCCTGCACTTCCCCGAGGGCGGCAG
CCTGGCCGCGCTGACCGCGCACCAGGCTTGCCACCTGCCGCTGGAGACTTTCACCCGTCATCGCCAGCCG
CGCGGCTGGGAACAACTGGAGCAGTGCGGCTATCCGGTGCAGCGGCTGGTCGCCCTCTACCTGGCGGCGC
GGCTGTCGTGGAACCAGGTCGACCAGGTGATCCGCAACGCCCTGGCCAGCCCCGGCAGCGGCGGCGACCT
GGGCGAAGCGATCCGCGAGCAGCCGGAGCAGGCCCGTCTGGCCCTGACCCTGGCCGCCGCCGAGAGCGAG
CGCTTCGTCCGGCAGGGCACCGGCAACGACGAGGCCAGCGCCGACGTGGTGAGCCTGACCTGCCCGGTCG
CCGCCGGTGAATGCGCGGGCCCGGCGGACAGCGGCGACGCCCTGCTGGAGCGCAACTATCCCACTGGCGC
GGAGTTCCTCGGCGACGGCGGCGACGTCAGCTTCAGCACCCGCGGCACGCAGAACTGGACGGTGGAGCGG
CTGCTCCAGGCGCACCGCCAACTGGAGGAGCGCGGCTATGTGTTCGTCGGCTACCACGGCACCTTCCTCG
AAGCGGCGCAAAGCATCGTCTTCGGCGGGGTGCGCGCGCGCAGCCAGGACCTCGACGCGATCTGGCGCGG
TTTCTATATCGCCGGCGATCCGGCGCTGGCCTACGGCTACGCCCAGGACCAGGAACCCGACGCGCGCGGC
CGGATCCGCAACGGTGCCCTGCTGCGGGTCTATGTGCCGCGCTCGAGTCTGCCGGGCTTCTACCGCACCG
GCCTGACCCTGGCCGCGCCGGAGGCGGCGGGCGAGGTCGAACGGCTGATCGGCCATCCGCTGCCGCTGCG
CCTGGACGCCATCACCGGCCCCGAGGAGGAAGGCGGGCGCCTGGAGACCATTCTCGGCTGGCCGCTGGCC
GAGCGCACCGTGGTGATTCCCTCGGCGATCCCCACCGACCCGCGCAACGTCGGCGGCGACCTCGACCCGT
CCAGCATCCCCGACCAGGAACAGGCGATCAGCGCCCTGCCGGACTACGCCAGCCAGCCCGGCAAACCGTC
GCGCGAGGACCTGAAGTA
Protein Sequence 
>gi|116049080|ref|YP_792118.1| exotoxin A [Pseudomonas aeruginosa UCBPP-PA14] MHLIPHWIPLVASLGLLAGGSFASAAEEAFDLWNECAKACVLDLKDGVRSSRMSVDPAIADTNGQGVLHYSMVLEGGNDALKLAIDNALSITSDGLTIRLEGGVEPNKPVRYSYTRQARGSWSLNWLVPIGHEKPSNIKVFIHELNAGNQLSHMSPIYTIEMGDELLAKLARDATFFVRAHESNEMQPTLAISHAGVSVVMAQTQPRREKRWSEWASGKVLCLLDPLDGVYNYLAQQRCNLDDTWEGKIYRVLAGNPAKHDLDIKPTVISHRLHFPEGGSLAALTAHQACHLPLETFTRHRQPRGWEQLEQCGYPVQRLVALYLAARLSWNQVDQVIRNALASPGSGGDLGEAIREQPEQARLALTLAAAESERFVRQGTGNDEASADVVSLTCPVAAGECAGPADSGDALLERNYPTGAEFLGDGGDVSFSTRGTQNWTVERLLQAHRQLEERGYVFVGYHGTFLEAAQSIVFGGVRARSQDLDAIWRGFYIAGDPALAYGYAQDQEPDARGRIRNGALLRVYVPRSSLPGFYRTGLTLAAPEAAGEVERLIGHPLPLRLDAITGPEEEGGRLETILGWPLAERTVVIPSAIPTDPRNVGGDLDPSSIPDQEQAISALPDYASQPGKPSREDLK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: toxA mutant is attenuated in burned mouse model (Rahme et al., 1995).
References
Rahme et al., 1995: Rahme LG, Stevens EJ, Wolfort SF, Shao J, Tompkins RG, Ausubel FM. Common virulence factors for bacterial pathogenicity in plants and animals. Science (New York, N.Y.). 1995; 268(5219); 1899-1902. [PubMed: 7604262].