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thrC

Victor ID 4246
Gene Name thrC
Sequence Strain (Species/Organism) Pseudomonas aeruginosa PAO1
NCBI Gene ID 880336
NCBI Protein GI 15598930
Locus Tag PA3735
Protein Accession NP_252424.1
Other Database IDs UniProtKB-ID: THRC_PSEAE
UniRef100: UniRef100_P29363
UniRef90: UniRef90_P29363
UniRef50: UniRef50_P29363
UniParc: UPI0000136EDB
EMBL: X65033
EMBL: AE004091
EMBL-CDS: CAA46168.1
EMBL-CDS: AAG07122.1
RefSeq_NT: NC_002516.2
GenomeReviews: AE004091_GR
KEGG: pae:PA3735
NMPDR: fig|208964.1.peg.3734
PseudoCAP: PA3735
HOGENOM: HBG521025
OMA: YYFTSAV
ProtClustDB: PRK09225
BioCyc: PAER208964:PA3735-MONOMER
Taxonomy ID 208964
Gene Starting Position 4186780
Gene Ending Position 4188189
Gene Strand (Orientation) -
Protein Name threonine synthase
DNA Sequence 
>gi|110645304:4186780-4188189 Pseudomonas aeruginosa PAO1 chromosome, complete genome
CTCAGAGCGGCTTGCCGCGATTGCCGTGCTGGCTGACGAAGGCCTGTACCTTGGCCAGCTCGTTCGGCAA
TACGGTGCAGCGCTCCTCGCGCTCGAACAGGTCGGCGAGGTGCGCAGGCAGCGCCGGTGCCTGGCCGATG
CCGGCCTTCTCCACCGCTTCGGGGAACTTGACCGGATGCGCAGTGCCCAGGGTCACCATCGGCACGCTCA
GGCTGCGCCGGCATTCGCGGGCGGCACGCACGCCAATGGCGGTGTGCGGGTCGAGCAACTCGCCACTGGA
GCGGTATACCTCGGCGATGGTCTCGCAGGTCTGCTCGTCGCTGACCGCCAGGGAGTCGAACAGCTTGCGC
GCCTCGGTCCAGCGCTGGTCTTCCACCGACAGCTTGCCGCTGGCCTTGAAGGCATCCAGCAGTTCGGCGA
CGGCCTTGCCGTTGCGGCCGTGCAGGTCGAACAGCAGGCGTTCGAAGTTGGACGAGACCATGATATCCAT
CGACGGCGACAGCGAGGGATGCAGGGTGTCCTTGTCGTAGCGATTACCGCTCATGAAGCGGTGCAGGATG
TCGTTGCGGTTGGTCGCGACGATCAGCTGGCTGACCGGCAGGCCCATGTTGCGCGCCAGGTAGCCGGCGA
AGATGTCGCCGAAGTTGCCGGTCGGCACCGAGAACGCCACCGAGCGATGCGGCGCGCCGAGCTGCAGCGC
GGCATGGAAGTAGTAGACGATCTGGGCCATGATCCGCGCCCAGTTGATCGAGTTCACCGCTACCAGGCGG
GTACCCTTGAGGAAGCCCTGGTCGGCGAAGCTGGCCTTGACCATCTCCTGGCAGTCGTCGAAGTTGCCTT
CGATGGCGATGTTGTGGATGTTGTCGCCGAGGATGGTGGTCATCTGCCGGCGCTGCACCTCGGACACGCG
GTTGTGCGGGTGCATGATGAAGATGTCGACGTTGTCGCAACGGCGGCAGCCTTCGATGGCCGCGGAGCCG
GTATCGCCGGAGGTGGCCCCCATGATCACCACACGCTCGCCGCGCTTGGCCAGCACATGGTCGAGCAGGC
GGCCGAGCAGTTGCAGGGCGAAATCCTTGAAGGCCAGGGTCGGGCCGTGGAACAGCTCCAGCACCCATTC
GTTGCCGTTCAACTGGCGCAGCGGCGCCACTGCGTCATGGGCGAAGACGCCATAGGTTTCCTCGAGGATC
TTCTTGAAGTCGGCATCGGCGATGCTGCCGGCGACGAACGGGCGCATCACCCGGAAGGCCAGCTCGTGGT
AGGGCAGGCCGACCCAGGAGGCGATCTCCTCGAGGGTGAAGCGTGGCAGGTTTTCCGGGACGTAGAGGCC
GCCGTCGCTGGCCAGGCCGGCGAGGAGGACATCTTCGAAGTTCAGGGCGGGCGCTTGGCCGCGGGTGCTG
ATGTAACGCA
Protein Sequence 
>gi|15598930|ref|NP_252424.1| threonine synthase [Pseudomonas aeruginosa PAO1] MRYISTRGQAPALNFEDVLLAGLASDGGLYVPENLPRFTLEEIASWVGLPYHELAFRVMRPFVAGSIADADFKKILEETYGVFAHDAVAPLRQLNGNEWVLELFHGPTLAFKDFALQLLGRLLDHVLAKRGERVVIMGATSGDTGSAAIEGCRRCDNVDIFIMHPHNRVSEVQRRQMTTILGDNIHNIAIEGNFDDCQEMVKASFADQGFLKGTRLVAVNSINWARIMAQIVYYFHAALQLGAPHRSVAFSVPTGNFGDIFAGYLARNMGLPVSQLIVATNRNDILHRFMSGNRYDKDTLHPSLSPSMDIMVSSNFERLLFDLHGRNGKAVAELLDAFKASGKLSVEDQRWTEARKLFDSLAVSDEQTCETIAEVYRSSGELLDPHTAIGVRAARECRRSLSVPMVTLGTAHPVKFPEAVEKAGIGQAPALPAHLADLFEREERCTVLPNELAKVQAFVSQHGNRGKPL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: thrC mutant is attenuated in rats (Potvin et al., 2003).
COG COG0498E, under E: Amino acid transport and metabolism
References
Potvin et al., 2003: Potvin E, Lehoux DE, Kukavica-Ibrulj I, Richard KL, Sanschagrin F, Lau GW, Levesque RC. In vivo functional genomics of Pseudomonas aeruginosa for high-throughput screening of new virulence factors and antibacterial targets. Environmental microbiology. 2003; 5(12); 1294-1308. [PubMed: 14641575].