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hfq from Pseudomonas aeruginosa PAO1

Victor ID 4214
Gene Name hfq from Pseudomonas aeruginosa PAO1
Sequence Strain (Species/Organism) Pseudomonas aeruginosa PAO1
NCBI Gene ID 878015
NCBI Protein GI 15600137
Locus Tag PA4944
Protein Accession NP_253631.1
Other Database IDs UniProtKB-ID: HFQ_PSEAE
UniRef100: UniRef100_A6VD57
UniRef90: UniRef90_A4XPY7
UniRef50: UniRef50_A4W5R3
UniParc: UPI000012C6A3
EMBL: AE004091
EMBL-CDS: AAG08329.1
RefSeq_NT: NC_002516.2
PDB: 1U1S
PDB: 1U1T
PDB: 3INZ
PDB: 3M4G
GenomeReviews: AE004091_GR
KEGG: pae:PA4944
PseudoCAP: PA4944
HOGENOM: HBG645207
OMA: PYLNVLR
ProtClustDB: PRK00395
BioCyc: PAER208964:PA4944-MONOMER
Taxonomy ID 208964
Gene Starting Position 5548396
Gene Ending Position 5548644
Gene Strand (Orientation) -
Protein Name RNA-binding protein Hfq
DNA Sequence 
>gi|110645304:5548396-5548644 Pseudomonas aeruginosa PAO1 chromosome, complete genome
GTCAAGCGTTGCCCGGCTCGGCCGGCTGGTCACCGCTCGGCAGACGCACCGGACGGCTCGGTACCACGGT
GGAGATCGCGTGCTTGTAAACCATCTGGCTGACGGTGTTCTTCAGCAGGATGACAAACTGGTCGAAAGAC
TCGATCTGGCCTTGCAGCTTGATGCCGTTGACCAGATAGATGGAAACCGGGACGCGTTCTTTCCGCAGGG
TATTGAGGTAAGGGTCTTGTAGCGAATGCCCTTTTGACA
Protein Sequence 
>gi|15600137|ref|NP_253631.1| RNA-binding protein Hfq [Pseudomonas aeruginosa PAO1] MSKGHSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRLPSGDQPAEPGNA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: When compared to PAO1 wild-type and the rpoS- mutant, the hfq- mutant decreased virulence in Galleria mellonella by a factor of 1 x 10(4) and 5 x 10(3), respectively. Likewise, when compared to wild-type, the PAO1hfq- mutant was significantly attenuated in virulence when administered intraperitoneally in mice (Sonnleitner et al., 2003).
COG COG1923R, under R: General function prediction only
References
Sonnleitner et al., 2003: Sonnleitner E, Hagens S, Rosenau F, Wilhelm S, Habel A, Jäger KE, Bläsi U. Reduced virulence of a hfq mutant of Pseudomonas aeruginosa O1. Microbial pathogenesis. 2003; 35(5); 217-228. [PubMed: 14521880].