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plcH

Victor ID 4426
Gene Name plcH
Sequence Strain (Species/Organism) Pseudomonas aeruginosa UCBPP-PA14
NCBI Gene ID 4385302
NCBI Protein GI 116048767
Locus Tag PA14_53360
Protein Accession YP_792433.1
Other Database IDs UniProtKB-ID: Q02I03_PSEAB
UniRef100: UniRef100_Q02I03
UniRef90: UniRef90_P06200
UniRef50: UniRef50_P06200
UniParc: UPI000045D054
EMBL: CP000438
EMBL-CDS: ABJ10003.1
RefSeq_NT: NC_008463.1
GenomeReviews: CP000438_GR
KEGG: pau:PA14_53360
NMPDR: fig|208963.3.peg.2476
eggNOG: COG3511
HOGENOM: HBG565180
OMA: EENISPW
ProtClustDB: CLSK866160
BioCyc: PAER208963:PA14_53360-MONOMER
Taxonomy ID 208963
Gene Starting Position 4730155
Gene Ending Position 4732347
Gene Strand (Orientation) +
Protein Name hemolytic phospholipase C precursor
DNA Sequence 
>gi|116048575:4730155-4732347 Pseudomonas aeruginosa UCBPP-PA14, complete genome
GATGACCGAAAACTGGAAATTCCGCCGTCGAACCTTTCTCAAGCACGGCGCCCAGGCCGCTACCCTGGCC
GGCCTTTCCGGGCTGTTCCCGGAGACGCTCCGGCGCGCCCTGGCCATCGAGCCGGACATCCGCACCGGAA
CCATCCAGGACGTCCAGCACGTGGTCATCCTGATGCAGGAGAACCGCAGCTTCGATCACTACTTCGGCCA
CCTCAACGGCGTCCGCGGCTTCAACGATCCTCGCGCGCTCAAGCGCCAGGACGGCAAGCCGGTCTGGTAC
CAGAACTACAAGTACGAGTTCTCCCCCTATCACTGGGATACCAAAGTCACCAGCGCCCAGTGGGTGAGTT
CGCAGAACCATGAATGGTCGGCCTTCCACGCGATCTGGAACCAGGGCCGCAACGACAAGTGGATGGCGGT
GCAGTACCCCGAAGCCATGGGCTACTTCAAGCGCGGCGACATTCCCTACTACTACGCCCTGGCCGACGCC
TTCACCCTGTGCGAGGCCTACCACCAGTCGATGATGGGCCCGACCAATCCGAACCGCCTCTACCACATGA
GCGGACGCGCCGCCCCCAGCGGCGACGGCAAGGACGTACACATCGGCAACGACATGGGCGACGGCACCAT
CGGCGCCAGCGGCACGGTGGACTGGACCACCTATCCCGAGCGGCTAAGCGCCGCTGGCGTGGACTGGCGG
GTCTACCAGGAAGGCGGCTACCGCTCCTCGTCACTCTGGTACCTGTACGTCGACGCCTACTGGAAATACC
GGCTCCAGGAGCAGAACAACTACGACTGCAACGCCCTCGCCTGGTTCAGGAACTTCAAGAACGCTCCGCG
CGATTCGGACCTCTGGCAGCGCGCCATGCTCGCCCGCGGCGTCGACCAGTTGCGCAAGGATGTGCAAGAA
AACACGCTGCCGCAGGTGTCCTGGATCGTCGCGCCCTACTGCTACTGCGAGCATCCCTGGTGGGGCCCCT
CGTTCGGCGAGTACTACGTGACCCGGGTGCTCGACGCGCTGACCAGCAACCCCGAGGTCTGGGCCAGGAC
CGTGTTCATCCTCAACTACGACGAGGGCGACGGCTTCTATGACCACGCCAGCGCCCCGGTGCCGCCGTGG
AAGGATGGCGTCGGCCTTTCCACGGTCAGCACCGCCGGCGAGATCGAGGCATCCAGCGGGCTGCCCATCG
GGCTCGGCCACCGCGTCCCGCTGATCGCCATCTCGCCCTGGTCGAAGGGCGGCAAGGTCAGCGCCGAAGT
GTTCGACCATACCTCGGTGCTGCGCTTCCTCGAACGCCGCTTCGGCGTCGTCGAGGAAAACATCTCGCCC
TGGCGGCGTGCCGTCTGCGGCGACCTGACTTCGCTGTTCGACTTCCAGGACGCAGGCGATACCCAGGTCG
CCCCCGACCTGACCAACGTCCCGCAGAGCGACGCGCGCAAGGAGGACGCCTACTGGCAGCAGTTCTACCG
GCCCAGCCCCAAGTACTGGTCCTACGAGCCCAAGAGCCTGCCCGGCCAGGAAAAGGGCCAGCGCCCTACC
CTCGCGGTGCCCTACCAGTTGCACGCCACGCTGGCCCTCGACATCGCCGCCGGCAAGCTGCGCCTGACCC
TGGGCAACGACGGCATGAGCCTGCCGGGCAATCCGCAGGGACACTCCGCTGCGGTATTCCAGGTGCAGCC
GCGGGAAGTCGGCAATCCGCGTTTCTATACCGTGACCAGCTATCCGGTGGTCCAGGAAAGCGGAGAGGAA
CTGGGCCGGACCCTCAACGACGAACTCGACGACCTGCTCGACGCCAACGGCCGCTACGCCTTCGAGGTGC
ACGGCCCCAACGGCTTCTTCCGCGAGTTCCACGGCAACCTGCATCTCGCCGCGCAGATGGCGCGGCCCGA
GGTATCGGTCACCTATCAACGCAACGGCAACCTGCAGTTGAACATCCGCAATCTCGGCCGCCTGCCGTGC
AGCGTGACGGTGACGCCGAACCCGGCCTATACCCAGGAGGGCAGCCGTCGCTATGAACTCGAACCGAACC
AGGCGATCAGTGAAGTGTGGCTGTTACGCAGCAGCCAGGGCTGGTACGACCTCAGCGTGACCGCCAGCAA
TACGGAAGCCAACTATCTCCGCCGCCTGGCCGGACACGTCGAGACCGGCAAGCCGAGCAGGAGCGATCCA
TTGCTCGACATCGCAGCGACCTG
Protein Sequence 
>gi|116048767|ref|YP_792433.1| hemolytic phospholipase C [Pseudomonas aeruginosa UCBPP-PA14] MTENWKFRRRTFLKHGAQAATLAGLSGLFPETLRRALAIEPDIRTGTIQDVQHVVILMQENRSFDHYFGHLNGVRGFNDPRALKRQDGKPVWYQNYKYEFSPYHWDTKVTSAQWVSSQNHEWSAFHAIWNQGRNDKWMAVQYPEAMGYFKRGDIPYYYALADAFTLCEAYHQSMMGPTNPNRLYHMSGRAAPSGDGKDVHIGNDMGDGTIGASGTVDWTTYPERLSAAGVDWRVYQEGGYRSSSLWYLYVDAYWKYRLQEQNNYDCNALAWFRNFKNAPRDSDLWQRAMLARGVDQLRKDVQENTLPQVSWIVAPYCYCEHPWWGPSFGEYYVTRVLDALTSNPEVWARTVFILNYDEGDGFYDHASAPVPPWKDGVGLSTVSTAGEIEASSGLPIGLGHRVPLIAISPWSKGGKVSAEVFDHTSVLRFLERRFGVVEENISPWRRAVCGDLTSLFDFQDAGDTQVAPDLTNVPQSDARKEDAYWQQFYRPSPKYWSYEPKSLPGQEKGQRPTLAVPYQLHATLALDIAAGKLRLTLGNDGMSLPGNPQGHSAAVFQVQPREVGNPRFYTVTSYPVVQESGEELGRTLNDELDDLLDANGRYAFEVHGPNGFFREFHGNLHLAAQMARPEVSVTYQRNGNLQLNIRNLGRLPCSVTVTPNPAYTQEGSRRYELEPNQAISEVWLLRSSQGWYDLSVTASNTEANYLRRLAGHVETGKPSRSDPLLDIAAT
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: plcH mutant is attenuated in burned mouse model (Rahme et al., 1995).
COG COG3511M, under M: Cell wall/membrane/envelope biogenesis
References
Rahme et al., 1995: Rahme LG, Stevens EJ, Wolfort SF, Shao J, Tompkins RG, Ausubel FM. Common virulence factors for bacterial pathogenicity in plants and animals. Science (New York, N.Y.). 1995; 268(5219); 1899-1902. [PubMed: 7604262].