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PA4489

Victor ID 4252
Gene Name PA4489
Sequence Strain (Species/Organism) Pseudomonas aeruginosa
NCBI Gene ID 881072
NCBI Protein GI 15599685
Locus Tag PA4489
Protein Accession NP_253179.1
Other Database IDs UniProtKB-ID: Y4489_PSEAE
UniRef100: UniRef100_Q9HVT2
UniRef90: UniRef90_Q9HVT2
UniRef50: UniRef50_Q8XE35
UniParc: UPI0000139DE5
EMBL: AE004091
EMBL-CDS: AAG07877.1
RefSeq_NT: NC_002516.2
GenomeReviews: AE004091_GR
KEGG: pae:PA4489
NMPDR: fig|208964.1.peg.4489
PseudoCAP: PA4489
HOGENOM: HBG374271
OMA: RWREPAK
ProtClustDB: CLSK868690
BioCyc: PAER208964:PA4489-MONOMER
Taxonomy ID 208964
Gene Starting Position 5020401
Gene Ending Position 5024951
Gene Strand (Orientation) -
Protein Name hypothetical protein
DNA Sequence 
>gi|110645304:5020401-5024951 Pseudomonas aeruginosa PAO1 chromosome, complete genome
ATCACTCGACCTTGACCTTGGCCAGCGCCGGCTTGGCTTCCAGGGCCTGCTGTTCCGGCGCGTAGAGACG
CAGGTAGCGGGCCGGTGGCAGGTTGAAGCTGCCTTTCTGGGAGAAACGCACCAGGTGACGGAAACGCTGC
TCGCCACTCAGGCTGTCCACCGGCACCCCGTAGAACAACTCGCCCGGTTCGTTGCGCGCGCGCTCCAGGG
TGGTCGCTTCGTCGCCGGCCAGGCCGCTGATCTTGATGCCCCAGGTGGTGCGCTCGACATCCGCGCCGGG
CGGCAGCGGCAATTCCAGCATGCCGTAGCGTAGAGCGGTGTCTTCCGGAACGTTCAGGGTCACTTCGTCG
AGATACAGTTCGTCGCTGGAAAGCGGCTTGTCGCCAACCTCCTCGACCTTGAACTCGAACGCCCCCTCAC
CGGGCACCAGGCGCAGCAGACGACGGCTGATCTGCACCGGCAGTTGCCCGCTCGGCGCCTGGGCGCTGCG
GTAGCTGAGCGCAACCGGCAACGGCCGGGCCGGCGCCTCGTCCAGGTCGACCCAGCTCGGAATGCCGCGG
CCGCGCCATTGCCAGTAGGTTTCGCCGCTGGCGCCGCGCTGCGCCTGCCAGTCCTTCGGCGGCTGCGGCA
GCTTGCCCTGCGGCGCCTGGGCCAGGGCGCCCTGCAGCCAGGTCAGGGCCAGGGCGCGTTCCAGGGTCGA
TTGCGCCGGCGCCAGGCGTTGCAGCAGAGCGCTGGCCTGCTGGCCATCCACGGCCGAGCGAGAGGCCAGC
AAGGCATCGGTGAACGGCAAGCCGGCCTCACGCAGGCGCTGCGTCGCCGTCTCGGCCTGGGCGGCCAGCG
GCGCGGGCACCGCGACCCGCAGTTGCCGTGCAAGGTCCACCGCCAGCACTCGCGCCGCGGCCAGGCCGAC
GGCCGAGTCCGGGTCGCCCAGCACCAGGCCGTCGTCGGCCTCCAGCGGCTCCGCGCGCGCCTGCCCTTCG
CCGGCGTTGGCCAGATCGTTGAGCAGGCCGCCGAGCAGGGTGTTCACCGGCAATTGCATGTCGCGGGCGA
AAGCCAGGATCAGCGCACGCTGCAGCAGCGGGGTCTGCGTCGCCTGCTTGGCGTAGGGCTCGAGGATGCG
CTGCCAGTGTTCGGCCGGCAGTTGGATCTCCAGTGCGCGGCTGGCGTACCAGTCGGCGTAGTAGGCGTAG
GCGGTGAGGAAAGCGTCGCCATCGACGTCGCCACCCCACCAGGCGAACCAGGCGTCCGGGCCGGCCATCT
GCACCAGGCGCAGGCGACTGTTCTGCATGATCAGGCGCAGGCGGTCGCGAATCCGCGGCTCGCCGCCGGC
CAGCGCCGGATAGGCGATGCTCAGCGGCAGCAGTTGGCTGGCGGTCTGCTCGACGCCGCCGTAGGGATAC
TCCAGCAGATCATCGAGATTGCCCAGGTAGGCAGCGGCCGGGCCATCGGCCAGGCGCAGGCGTACGTCGC
GCGCGTCCGCCGGCAGTTGCAGCGGGTTGCTCGCCGCCGCCAGGCTGAGGTTCTGCATCTGCTCCACCTG
CCAGCCGTCGGCCAGCAGGTTGAAGCGCACCGCCAGGCGGTCGCGGACCTGCCCGTCCTGGCGCAACTCG
GCGCTCCAGTCGCCATCGCTGAGCGGCTGTTGCGCCAGCGGAATGTAGTTGACTCCCTTGGCCAGCTCCA
GGGTCTGGCTGCGCTGGCTGCCAGGCGGCCCGCTGAGCAGCTCGGCCTTGACCGGCTGTTCGCCCTGGTT
GAAGACGAACAGGCCGAGGTCGGGCTGGTCACCCTGGCGGAAGCGAGTCGGCCCGCTCCACTTCAGGTAC
AGCGGCTTCTCCGAGCGAAGGAACTGCTTCTTCTGGCCGACCTGGCCGTTGTCGTCGATGGCCCGCGCGG
TGATCCGCCAGCGGGTCAGCGAGTCGGGCATGCGGAAGCTGAAGCTGGCCTTGCCCTGGGCGTCGGTGAC
CAGCTCCGGCTGCCAGGCGGCGGTGTCGACGTCCTCGCGGCGCGGCCGCTCCAGTACCTTGACGCCGCGC
TCGCTGCGGTTCGCCCGTCCGGGTGCGCTGGTGCTGCCGGGCAACGCCACGTCGTAGCTGATGAAGGCCA
GGCTGGCGCTGGTGCGCACGTTGTTGCGCCGCGGATGGTAGAAGAACTGGTCGATGCCGGGGGCGATCTC
CGCCTGCAGGGCATAGACCATCTCATCCACCACGCTGACGGTCAGGTGGCTGGAAACCGGTTTGCCGGCG
AAGCGCGTGGCCAGGGTCACGGTCACCGTCTCGCCCGGTTCGTAGCGCTCCTTGTCGGTGGCGATGTCGA
TCTCTACCTGGGGCATGCCGACCTTGATCCCGGCGTTCTGGAAGCTGTAGTCGCCGCCCTTGGTGTAGAG
CACCGAGAAGGTCAGGTTCGGCGAGAACTCCTCGCGCACCGGGATCCACACGCGGTACTGGGTCGGATTG
AGCTTTTCCAGGCGCAGCCAGTCGGCGCCCTTGGACAGCAGGGCGGTGGCCTCGACCTTGTCGCGCTCCA
GGGACAACAGCGCATCCTCCACCGGCTCGGGGAAGGTGATCAGTGCGGAGGCTTCCTCGCCGGTGCGGTA
CTCGGGCTTGTCGAACACCACCTCGACGGTGCCCGGCACCGACTTCACGCCCTCGCCGCTCACCGAGTGG
CCGGTAGCGCCAAGGAGCTGGCCCTTGTCGTCGCGCAGCTCCACGGAATAGGTACCGGGGCGCTCGAAGG
TCAGCGCGAAGCGGCCGTCGGCGACCGGACCGCTGTCGGTGGCGCGGTCCTCCAGGCGGATCCACTGGTA
GCTGCTCGGCTTGAGCGGGGTCGGCTGTTCGCTGGCATAGCTGAACTCGACCTTCTCGCCGGCGGCGCTG
AAGCGCTGCGGCGCGCTCAGGCGGTAGCGCGCGGCGCCGCGCTCGATGAGGATCTCCTTGCTGGTCTTGA
CCCGGTAGGCGGCGCCGTCGCTGGCGAAGATGGTCAGCATGTAGCGACTGGGTTTCTCGGCCGGCGGCAA
TTCGATGGCGGCGCGACCCTTGCCGTCGGTGGTCAGTTCGGTGCTGCTCAGTTCCACCGGGAACTGGCCG
AGATACTGCAGTTCGTTGTCCACCATCGACAACTGCTGGGCGCGCAGGCTCAGTTGCAGGCGCGCGTTGG
CCACCGGCTTGCCGTCCGGATAGAGCAGGACGATCTCGCCCTTCACCGGCTCGGCGGTCTTGAAGTCCGG
CTTGGCCAGGTCGAGGGCGACTTCGAAGTGCGGCTTGATGTATTCGGCGACGCGGAAGGCGCTGCTGTAG
GTCTGCCCGCGGTAGTCGAAGCGCAACTCGTAGCCGCCGGCGACGGCGTTCTCCGGCAGTTGGAAGCGGC
CATTGGCGCCGCTCTTCGCGTCGAAGCGGAGGTCCAGGCTTTGCAATACCGTGCCGCTGGCGTCGATCAC
GCTCAGGCGCACCGGCGCGCTGGCGGCGGCCTGGGATTGCCGGGCGTCCTTGAACTCGCGGCCGACCATC
TTCAACGAGACCCAGTCGCCCGGCCGGTACAGCGGGCGGTCGGTGAAGGCGTAGATCTTGGTGTCGTAGA
TCTCGCTGTCGTAATAGAAGTTCTCGGAGACGAAGACCCCGCCCTCGCGGTCCTCGCCGATCACGTAGGA
GCGCTCCGGACTGGCGTGCTTGAGCCGCAGCAGGCCGTCGGCGTCGGTATTGCCGCTGCTCATCACGCCC
AGGCCGTCGGTCCACAGCACCTTGGTGTCGGGCACCGGGGTGCCTTCGTGCTTGCGTGCGGTCCAGACCA
GCAGCTCGTCGCCGGCGACCTTGCTCACCGCCACGCTGTTGGAGACGAACACCACGGTGGTGGCGCGGTA
CTTGCCGACAAGCGCCTCGACCAGGTACAGGCCCGGCTTCAGCTTGCCCAGCGGGATGTAGACATTGCCC
GGCACGACGTTGATGAACTCGCTGGAGGAACCGGCCAGCTTGACGTCCTGCGGCGGCTCGATGGGCTTGG
CGTCCCACAGCGGATAGCGGAACTGGCTGACCAGCGGCAGGCCGGGAATCGGCGCGTATTGCGGCTGCGC
GTCGTAGGGCGTCGGCGCGGTCATGGCGTTGCCCATCTTCAGCTCGGGCACCGCCTCGGTGACCTGTTGC
CGCGACTCGTAGGAGAAGGCGCGCTGCATCACCCGGCGCGACTTGCGATACCAGTTGTCCCAGAGATAGG
CCAGGGTGTTCGACAGGCCTTCGCCCTTGAACTGTCCCTCGGCCAGGACCCGGTGCAGGTTCTTCTGCCG
CTTGAGGAACTCCAGCGGCTGTTCGATCCGGTACAGGCGCACGTCGACCCCGCCATAGGGCTCCATGCGG
TAGCGCCGGTAGTCGCGGCCGGGCGCTTCGAGACGGACCCGCGCTTCCTCGTCGGTGGCGAAGCTGCTGT
CGGCGAGCAGGAAGAAGGATTCGCCGGCCATCGGCGTGTAGCCGCTCGGTTCCACCGTGTCTTCCGCCTG
GACGGCGGCGAACGGCAGCAGGACCAGGGCGGCGACCGCCAGGCTACGGCTGAAACGGCGCAGGTTGCTC
A
Protein Sequence 
>gi|15599685|ref|NP_253179.1| hypothetical protein PA4489 [Pseudomonas aeruginosa PAO1] MSNLRRFSRSLAVAALVLLPFAAVQAEDTVEPSGYTPMAGESFFLLADSSFATDEEARVRLEAPGRDYRRYRMEPYGGVDVRLYRIEQPLEFLKRQKNLHRVLAEGQFKGEGLSNTLAYLWDNWYRKSRRVMQRAFSYESRQQVTEAVPELKMGNAMTAPTPYDAQPQYAPIPGLPLVSQFRYPLWDAKPIEPPQDVKLAGSSSEFINVVPGNVYIPLGKLKPGLYLVEALVGKYRATTVVFVSNSVAVSKVAGDELLVWTARKHEGTPVPDTKVLWTDGLGVMSSGNTDADGLLRLKHASPERSYVIGEDREGGVFVSENFYYDSEIYDTKIYAFTDRPLYRPGDWVSLKMVGREFKDARQSQAAASAPVRLSVIDASGTVLQSLDLRFDAKSGANGRFQLPENAVAGGYELRFDYRGQTYSSAFRVAEYIKPHFEVALDLAKPDFKTAEPVKGEIVLLYPDGKPVANARLQLSLRAQQLSMVDNELQYLGQFPVELSSTELTTDGKGRAAIELPPAEKPSRYMLTIFASDGAAYRVKTSKEILIERGAARYRLSAPQRFSAAGEKVEFSYASEQPTPLKPSSYQWIRLEDRATDSGPVADGRFALTFERPGTYSVELRDDKGQLLGATGHSVSGEGVKSVPGTVEVVFDKPEYRTGEEASALITFPEPVEDALLSLERDKVEATALLSKGADWLRLEKLNPTQYRVWIPVREEFSPNLTFSVLYTKGGDYSFQNAGIKVGMPQVEIDIATDKERYEPGETVTVTLATRFAGKPVSSHLTVSVVDEMVYALQAEIAPGIDQFFYHPRRNNVRTSASLAFISYDVALPGSTSAPGRANRSERGVKVLERPRREDVDTAAWQPELVTDAQGKASFSFRMPDSLTRWRITARAIDDNGQVGQKKQFLRSEKPLYLKWSGPTRFRQGDQPDLGLFVFNQGEQPVKAELLSGPPGSQRSQTLELAKGVNYIPLAQQPLSDGDWSAELRQDGQVRDRLAVRFNLLADGWQVEQMQNLSLAAASNPLQLPADARDVRLRLADGPAAAYLGNLDDLLEYPYGGVEQTASQLLPLSIAYPALAGGEPRIRDRLRLIMQNSRLRLVQMAGPDAWFAWWGGDVDGDAFLTAYAYYADWYASRALEIQLPAEHWQRILEPYAKQATQTPLLQRALILAFARDMQLPVNTLLGGLLNDLANAGEGQARAEPLEADDGLVLGDPDSAVGLAAARVLAVDLARQLRVAVPAPLAAQAETATQRLREAGLPFTDALLASRSAVDGQQASALLQRLAPAQSTLERALALTWLQGALAQAPQGKLPQPPKDWQAQRGASGETYWQWRGRGIPSWVDLDEAPARPLPVALSYRSAQAPSGQLPVQISRRLLRLVPGEGAFEFKVEEVGDKPLSSDELYLDEVTLNVPEDTALRYGMLELPLPPGADVERTTWGIKISGLAGDEATTLERARNEPGELFYGVPVDSLSGEQRFRHLVRFSQKGSFNLPPARYLRLYAPEQQALEAKPALAKVKVE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: PA4489 mutant is attenuated in rats (Potvin et al., 2003).
COG COG2373R, under R: General function prediction only
References
Potvin et al., 2003: Potvin E, Lehoux DE, Kukavica-Ibrulj I, Richard KL, Sanschagrin F, Lau GW, Levesque RC. In vivo functional genomics of Pseudomonas aeruginosa for high-throughput screening of new virulence factors and antibacterial targets. Environmental microbiology. 2003; 5(12); 1294-1308. [PubMed: 14641575].