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estA

Victor ID 4222
Gene Name estA
Sequence Strain (Species/Organism) Pseudomonas aeruginosa PAO1
NCBI Gene ID 878826
NCBI Protein GI 15600305
Locus Tag PA5112
Protein Accession NP_253799.1
Other Database IDs UniProtKB-ID: ESTA_PSEAE
UniRef100: UniRef100_O33407
UniRef90: UniRef90_O33407
UniRef50: UniRef50_O33407
UniParc: UPI00000D426D
EMBL: AF005091
EMBL: AJ277638
EMBL: AE004091
EMBL-CDS: AAB61674.1
EMBL-CDS: CAC14200.1
EMBL-CDS: AAG08497.1
RefSeq_NT: NC_002516.2
PDB: 3KVN
TCDB: 1.B.12.8.1
GenomeReviews: AE004091_GR
KEGG: pae:PA5112
PseudoCAP: PA5112
HOGENOM: HBG639316
OMA: WLLPDIG
ProtClustDB: CLSK869124
BioCyc: PAER208964:PA5112-MONOMER
Taxonomy ID 208964
Gene Starting Position 5754297
Gene Ending Position 5756237
Gene Strand (Orientation) -
Protein Name esterase EstA
DNA Sequence 
>gi|110645304:5754297-5756237 Pseudomonas aeruginosa PAO1 chromosome, complete genome
TTCAGAAGTCCAGGCTCAGCGCCAGGCTGACGCTCTGCTGGGTATCGTCCTCGCCCTTGCGCCAGTTGTA
GCCGCCGCGCAGCGACAGCTCCGGCGCCAGCTTCTGGCTGAAGCCGAGTGAGACGCGGTTGAGATGGTCC
TGCGGGGTGTAGCCTTCGAGGGTGAAGCGATTGCCCGGCAGGCTGTTGAGGGACATGGTCAGGTCCTGGG
TGTCGTCCTCGTACTCACGTTCGTGGGCGTACTCGGCGAACAGCTGGGTATCGCTGCCGAACGCGTACTT
GCCTTGCAGGCCGGCGCCCAGGCGCTTCGAGCTGCGCTTCTGGTCGTCGTAGTCGAGCGCGGTGGCGCTG
GCGCCCTTCTCGGAATAGCCGTCGACCTCGACCCGTGCATAGTCGGCGCTGACGAACGGCGACAGGTGCC
AGGGACTGTCGGCCTGCTGGGCGATGTCGTAGCCCAGGCGCGCGCTGAACGCCCACAGGTGGCCGTTGGT
GTCGCCTTTCTCGCTGCGCTCGCCGCCGCCCAGGGCGAACTTGCGCTTCAGGTCGTCGTAGTCGAGGTAG
CCGCCGGTCAACGCCGCGTCGGCCCACCAGCGGTTTTCCTGGTACTGCACGAAGGCGCTGGCCATGTAGC
TGTTCATCCGGTAGTCGGAATCCTTGGCGCCGGCTTCCAGCTTCTGCCGGTAGAAACCGGCGGCGACCCC
GGCGCGCCAGGCCTCGTCGATGCGGTAGCTGCCACCAAGGGTCAGGTTGTAGCCGTTGCCGTCGCCGCTG
GCGGCGCTGTCCTGGGAGTCGAAGTCCAGGCGCTGGCCACCGCCGCCGACGAAGCCGCGCCACTGGCCGA
CGTTCTGCCAGTTCTCCCAGTCCGCCTGCCACTGGCTGCGCAGTTCGTCCTGGTAGGCACGCAGGGTGCC
GTGGGCCATTTCCGGCAGCAGGGTCAGCTCCCAGGGCGCCGACAGCAGCGAATAGGTGTAGTCGGCGATC
AGGCGCTGGCCGGTGATGGTCGGGTGCACGCTGTCGTTGAACAGCAATTTGCTCGGGTCGGGCGTGCTGC
CGTTGATCCCGTAGGTCGGGTTCATGGTGCAGCCGTTGCCGCTGAAACAGGTGCCGATCAGGTTCTGGTC
GGCGGCCAGGCCGAAGGAAGCCGGGTTGGCCATGCCTTCCTTGAGCAGCAGCGGGATGTTCAACGGAATG
ACGTTGGCGCCGGCCTGGCTCAACTGGGCGGTCAGCTCGGCGTTGAACGTGCCGCTGAGTTGGCTGGCGA
AAGGCTGCAAGGGACCACCGAAGGTAGCCGGGGTCAGGCCCAGGTCGGGCAACAGCCAGACCACGATGTA
GCGCGCGCCGGCCTGCTGCAGGGCCTGCACGCTATCCACCAGGCGACCGGCGGCCTGTTGGGCCTGGACG
TCGTTGAGGATGCGCCCCTGGAGAAAGTCGTTGCCGCCGCCGGTGATGTAGTACAACGCGTTCGGGTCGG
CACCCAGGCCCTGGCGGGCACGGTCCACCAGGTAGCCATCGCGGCTGCGCAGGAGGGTATTGTCGCGCTC
GATCAGCGAGCCGTTGGCCGCGGTGATCGAGTCGTAGATCTGATCGGTCCGGTAGCCGCCCACCGCCCAG
TTGTTGCCGTCGGCGATGCCCTGCTGGGCGTTGACCGGCGAGGTCGAGGCAGCCAGGTCACCCGGGGCGA
TGCCGAGCTGATTGCCGAGCAGCATGGGCGCGGTCGGTCCGAAGATCTCGCCGCTGCCGTTCTGGTAGGT
CGGGCCGACCCGGTTGGTGAAACGCGAGGTGCTTCCGGCGGGGCCGGCAGGATCGGGGAACTGCCCGGCA
TCGCTGAGGCTGTCGCCGAACACCACCAGCGTCGAATAGGGCGAAGGAGCAGCCTGCGGGGCGGTGGACA
GCGAAGCCAGCAGGCAGGCCGCTACCAGTGGCTTGAGCGCCATTCTGATCA
Protein Sequence 
>gi|15600305|ref|NP_253799.1| esterase [Pseudomonas aeruginosa PAO1] MIRMALKPLVAACLLASLSTAPQAAPSPYSTLVVFGDSLSDAGQFPDPAGPAGSTSRFTNRVGPTYQNGSGEIFGPTAPMLLGNQLGIAPGDLAASTSPVNAQQGIADGNNWAVGGYRTDQIYDSITAANGSLIERDNTLLRSRDGYLVDRARQGLGADPNALYYITGGGNDFLQGRILNDVQAQQAAGRLVDSVQALQQAGARYIVVWLLPDLGLTPATFGGPLQPFASQLSGTFNAELTAQLSQAGANVIPLNIPLLLKEGMANPASFGLAADQNLIGTCFSGNGCTMNPTYGINGSTPDPSKLLFNDSVHPTITGQRLIADYTYSLLSAPWELTLLPEMAHGTLRAYQDELRSQWQADWENWQNVGQWRGFVGGGGQRLDFDSQDSAASGDGNGYNLTLGGSYRIDEAWRAGVAAGFYRQKLEAGAKDSDYRMNSYMASAFVQYQENRWWADAALTGGYLDYDDLKRKFALGGGERSEKGDTNGHLWAFSARLGYDIAQQADSPWHLSPFVSADYARVEVDGYSEKGASATALDYDDQKRSSKRLGAGLQGKYAFGSDTQLFAEYAHEREYEDDTQDLTMSLNSLPGNRFTLEGYTPQDHLNRVSLGFSQKLAPELSLRGGYNWRKGEDDTQQSVSLALSLDF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: estA mutant is attenuated in rats (Potvin et al., 2003).
COG COG3240IR, under I: Lipid transport and metabolism; R: General function prediction only
References
Potvin et al., 2003: Potvin E, Lehoux DE, Kukavica-Ibrulj I, Richard KL, Sanschagrin F, Lau GW, Levesque RC. In vivo functional genomics of Pseudomonas aeruginosa for high-throughput screening of new virulence factors and antibacterial targets. Environmental microbiology. 2003; 5(12); 1294-1308. [PubMed: 14641575].