| Victors ID |
Gene Name |
Sequence Strain (Species/Organism) |
NCBI Gene ID |
NCBI Nucleotide GI |
NCBI Protein GI |
Locus Tag |
Genbank Accession |
Protein Accession |
Protein Name |
Molecule Role |
Molecule Role Annotation |
PMID |
|
|
yibK |
Actinobacillus pleuropneumoniae L20 |
4848512
|
|
126207549
|
APL_0061 |
CP000569 |
YP_001052774 |
putative tRNA/rRNA methyltransferase |
Virulence factor |
MUTATION: yibK mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
dnaK from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4848587
|
|
126209366
|
APL_1906 |
|
YP_001054591.1 |
molecular chaperone DnaK |
Virulence factor |
MUTATION: dnaK mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
nqrA from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4848604
|
|
126207638
|
APL_0150 |
|
YP_001052863.1 |
Na(+)-translocating NADH-quinone reductase subunit A |
Virulence factor |
MUTATION: ngrA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
aroA from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4848647
|
|
126208179
|
APL_0699 |
|
YP_001053404.1 |
3-phosphoshikimate 1-carboxyvinyltransferase |
Virulence factor |
MUTATION: aroA mutant is attenuated in pigs [Ref6876:Garside et al., 2002]. |
12027598
|
|
|
fur from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4848648
|
|
126208686
|
APL_1218 |
|
YP_001053911.1 |
ferric uptake regulation protein |
Virulence factor |
MUTATION: fur mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
moaA from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4848653
|
|
126208170
|
APL_0690 |
|
YP_001053395.1 |
molybdenum cofactor biosynthesis protein A |
Virulence factor |
MUTATION: moaA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
pntB from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4848714
|
|
126208317
|
APL_0841 |
|
YP_001053542.1 |
pyridine nucleotide transhydrogenase |
Virulence factor |
MUTATION: pntB mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
dksA from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4848733
|
|
126207663
|
APL_0175 |
|
YP_001052888.1 |
DnaK suppressor protein |
Virulence factor |
MUTATION: dksA mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
napB from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4848740
|
|
126208890
|
APL_1426 |
|
YP_001054115.1 |
nitrate reductase cytochrome c-type subunit |
Virulence factor |
MUTATION: napB mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
ilvI from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4848759
|
|
126208207
|
APL_0727 |
|
YP_001053432.1 |
acetolactate synthase 3 catalytic subunit |
Virulence factor |
MUTATION: ilvl mutant is attenuated in pigs [Ref6877:Subashchandrabose et al., 2009]. |
19703979
|
|
|
mrp from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4848795
|
|
126208474
|
APL_1000 |
|
YP_001053699.1 |
putative ATPase |
Virulence factor |
MUTATION: mrp mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
htpG from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4848844
|
|
126208461
|
APL_0987 |
|
YP_001053686.1 |
heat shock protein 90 |
Virulence factor |
MUTATION: htpG mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
thrC from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4848887
|
|
126208963
|
APL_1499 |
|
YP_001054188.1 |
threonine synthase |
Virulence factor |
MUTATION: thrC mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
recR from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4848935
|
|
126207562
|
APL_0074 |
|
YP_001052787.1 |
recombination protein RecR |
Virulence factor |
MUTATION: recR mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
frpB from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4848963
|
|
126207764
|
APL_0276 |
|
YP_001052989.1 |
iron-regulated outer membrane protein B |
Virulence factor |
MUTATION: frpB mutant is avirulent in pigs [Ref6878:Buettner et al., 2009]. |
19343711
|
|
|
cpxD from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849025
|
|
126209046
|
APL_1582 |
|
YP_001054271.1 |
capsule polysaccharide export protein |
Virulence factor |
MUTATION: cpxD mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
cpxC from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849026
|
|
126209047
|
APL_1583 |
|
YP_001054272.1 |
capsule polysaccharide export inner-membrane protein |
Virulence factor |
MUTATION: cpxC mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
pnp from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849054
|
|
126208059
|
APL_0577 |
|
YP_001053284.1 |
polynucleotide phosphorylase/polyadenylase |
Virulence factor |
MUTATION: pnp mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
irp from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849145
|
|
126208395
|
APL_0919 |
|
YP_001053620.1 |
iron-regulated outer membrane protein |
Virulence factor |
MUTATION: irp mutant is attenuated in competitive index experiment in pig infection model [Ref6877:Subashchandrabose et al., 2009]. |
19703979
|
|
|
fkpA |
Actinobacillus pleuropneumoniae L20 |
4849158
|
|
126209104
|
APL_1640 |
CP000569 |
YP_001054329 |
putative FKBP-type peptidyl-prolyl cis-trans isomerase |
Virulence factor |
MUTATION: fkpA mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
argG from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849166
|
|
126207906
|
APL_0422 |
|
YP_001053131.1 |
argininosuccinate synthase |
Virulence factor |
MUTATION: argG mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
dmsA from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849184
|
|
126209138
|
APL_1674 |
|
YP_001054363.1 |
anaerobic dimethyl sulfoxide reductase chain A precursor |
Virulence factor |
MUTATION: dmsA mutant is attenuated in pigs [Ref6879:Baltes et al., 2003]. |
14638764
|
|
|
corC from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849211
|
|
126207856
|
APL_0372 |
|
YP_001053081.1 |
magnesium and cobalt efflux protein |
Virulence factor |
MUTATION: corC mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
mglA from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849247
|
|
126208883
|
APL_1419 |
|
YP_001054108.1 |
galactose/methyl galaxtoside transporter ATP-binding protein |
Virulence factor |
MUTATION: mglA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
tbpA |
Actinobacillus pleuropneumoniae L20 |
4849278
|
|
126209031
|
APL_1567 |
CP000569 |
YP_001054256 |
transferrin-binding protein 1 Tbp1 |
Virulence factor |
MUTATION: tbpA mutant is attenuated in pigs [Ref6880:Baltes et al., 2002]. |
12007819
|
|
|
dnaJ from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849429
|
|
126209365
|
APL_1905 |
|
YP_001054590.1 |
chaperone protein DnaJ |
Virulence factor |
MUTATION: dnaJ mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
galU from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849515
|
|
126208131
|
APL_0651 |
|
YP_001053356.1 |
UTP--glucose-1-phosphate uridylyltransferase |
Virulence factor |
MUTATION: galU mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
aroQ from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849643
|
|
126209324
|
APL_1862 |
|
YP_001054549.1 |
3-dehydroquinate dehydratase |
Virulence factor |
MUTATION: aroQ mutant is attenuated in pigs [Ref6881:Ingham et al., 2002]. |
11731178
|
|
|
tig from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849723
|
|
126208971
|
APL_1507 |
|
YP_001054196.1 |
trigger factor |
Virulence factor |
MUTATION: tig mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
lpdA from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849746
|
|
126208249
|
APL_0771 |
|
YP_001053474.1 |
dihydrolipoamide dehydrogenase |
Virulence factor |
MUTATION: lpdA mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
hgbA from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849777
|
|
126208521
|
APL_1047 |
|
YP_001053746.1 |
hemoglobin-binding protein A precursor |
Virulence factor |
MUTATION: hgbA mutant is attenuated in pigs [Ref6882:Shakarji et al., 2006]. |
16699590
|
|
|
exbB |
Actinobacillus pleuropneumoniae L20 |
4849793
|
|
126209034
|
APL_1570 |
CP000569 |
YP_001054259 |
biopolymer transport ExbB protein |
Virulence factor |
MUTATION: exbB mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
hemA from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849853
|
|
126207888
|
APL_0404 |
|
YP_001053113.1 |
glutamyl-tRNA reductase |
Virulence factor |
MUTATION: hemA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
apxIC |
Actinobacillus pleuropneumoniae L20 |
4849898
|
|
126208909
|
APL_1445 |
|
YP_001054134.1 |
RTX-I toxin-activating lysine-acyltransferase ApxIC |
Virulence factor |
MUTATION: apxlC mutant is attenuated in mice [Ref6883:Xu et al., 2007]. |
18062275
|
|
|
guaA from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849920
|
|
126208074
|
APL_0592 |
|
YP_001053299.1 |
GMP synthase |
Virulence factor |
MUTATION: guaA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
prc from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849922
|
|
126207608
|
APL_0120 |
|
YP_001052833.1 |
carboxy-terminal protease |
Virulence factor |
MUTATION: prc mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
lon from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849930
|
|
126207860
|
APL_0376 |
|
YP_001053085.1 |
ATP-dependent protease La |
Virulence factor |
MUTATION: lon mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
hemE from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849940
|
|
126207600
|
APL_0112 |
|
YP_001052825.1 |
uroporphyrinogen decarboxylase |
Virulence factor |
MUTATION: hemE mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
dsbA from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4849992
|
|
126209330
|
APL_1868 |
|
YP_001054555.1 |
Thiol:disulfide interchange protein dsbA precursor |
Virulence factor |
MUTATION: dsbA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
hupA from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4850001
|
|
126207602
|
APL_0114 |
|
YP_001052827.1 |
DNA-binding protein HU |
Virulence factor |
MUTATION: hupA mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
atpG from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4850085
|
|
126209111
|
APL_1647 |
|
YP_001054336.1 |
F0F1 ATP synthase subunit gamma |
Virulence factor |
MUTATION: atpG mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
rpmF from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4850127
|
|
126208850
|
APL_1386 |
|
YP_001054075.1 |
50S ribosomal protein L32 |
Virulence factor |
MUTATION: rpmF mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
znuA from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4850149
|
|
126208904
|
APL_1440 |
|
YP_001054129.1 |
high-affinity zinc transporter periplasmic component |
Virulence factor |
MUTATION: znuA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
atpA from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4850203
|
|
126209112
|
APL_1648 |
|
YP_001054337.1 |
F0F1 ATP synthase subunit alpha |
Virulence factor |
MUTATION: atpA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
cpxB from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4850217
|
|
126209048
|
APL_1584 |
|
YP_001054273.1 |
capsule polysaccharide export inner-membrane protein |
Virulence factor |
MUTATION: cpxB mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
apxIA |
Actinobacillus pleuropneumoniae L20 |
4850247
|
|
126208908
|
APL_1444 |
|
YP_001054133.1 |
RTX-I toxin determinant A |
Virulence factor |
MUTATION: apxIA mutant is attenuated in mice [Ref6884:Xu et al., 2006]. |
16930871
|
|
|
visC from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4850274
|
|
126207817
|
APL_0333 |
|
YP_001053042.1 |
putative monooxygenase family protein |
Virulence factor |
MUTATION: visC mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
hlyX from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4850318
|
|
126208136
|
APL_0656 |
|
YP_001053361.1 |
fumarate/nitrate reduction transcriptional regulator |
Virulence factor |
MUTATION: hlyX mutant is attenuated in pigs [Ref6885:Baltes et al., 2005]. |
16040973
|
|
|
tbpB |
Actinobacillus pleuropneumoniae L20 |
4850335
|
|
126209032
|
APL_1568 |
CP000569 |
YP_001054257 |
transferrin-binding protein |
Virulence factor |
MUTATION: tbpB mutant is attenuated in pigs [Ref6880:Baltes et al., 2002]. |
12007819
|
|
|
atpH from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4850346
|
|
126209113
|
APL_1649 |
|
YP_001054338.1 |
F0F1 ATP synthase subunit delta |
Virulence factor |
MUTATION: atpH mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
luxS from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4850390
|
|
126208684
|
APL_1216 |
|
YP_001053909.1 |
S-ribosylhomocysteinase |
Virulence factor |
MUTATION: luxS mutant is attenuated in mice [Ref6886:Li et al., 2008]. |
18585450
|
|
|
arcA from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4850431
|
|
126207536
|
APL_0048 |
|
YP_001052761.1 |
two-component response regulator |
Virulence factor |
MUTATION: arcA mutant is attenuated in pigs [Ref6887:Buettner et al., 2008]. |
17881160
|
|
|
rpoE from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4850464
|
|
126207878
|
APL_0394 |
|
YP_001053103.1 |
RNA polymerase sigma factor RpoE |
Virulence factor |
MUTATION: rpoE mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
prfC from Actinobacillus pleuropneumoniae L20 |
Actinobacillus pleuropneumoniae L20 |
4850473
|
|
126207518
|
APL_0030 |
|
YP_001052743.1 |
peptide chain release factor 3 |
Virulence factor |
MUTATION: prfC mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
rpmF from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5850734
|
|
165976811
|
APJL_1404 |
|
YP_001652404.1 |
50S ribosomal protein L32 |
Virulence factor |
MUTATION: rpmF mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
thrC from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5850813
|
|
165976927
|
APJL_1524 |
|
YP_001652520.1 |
threonine synthase |
Virulence factor |
MUTATION: thrC mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
znuA from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5850850
|
|
165976875
|
APJL_1472 |
|
YP_001652468.1 |
high-affinity zinc transporter periplasmic component |
Virulence factor |
MUTATION: znuA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
visC from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5850858
|
|
165975791
|
APJL_0349 |
|
YP_001651384.1 |
monoxygenase |
Virulence factor |
MUTATION: visC mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
rpoE from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5850859
|
|
165975855
|
APJL_0415 |
|
YP_001651448.1 |
RNA polymerase sigma factor RpoE |
Virulence factor |
MUTATION: rpoE mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
atpA from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5850894
|
|
165977084
|
APJL_1681 |
|
YP_001652677.1 |
F0F1 ATP synthase subunit alpha |
Virulence factor |
MUTATION: atpA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
atpH from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5850906
|
|
165977085
|
APJL_1682 |
|
YP_001652678.1 |
F0F1 ATP synthase subunit delta |
Virulence factor |
MUTATION: atpH mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
hupA from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5850919
|
|
165975570
|
APJL_0115 |
|
YP_001651163.1 |
DNA-binding protein HU |
Virulence factor |
MUTATION: hupA mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
prc from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5850978
|
|
165975576
|
APJL_0121 |
|
YP_001651169.1 |
carboxy-terminal protease |
Virulence factor |
MUTATION: prc mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
napB from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851075
|
|
165976861
|
APJL_1458 |
|
YP_001652454.1 |
nitrate reductase cytochrome c-type subunit |
Virulence factor |
MUTATION: napB mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
mglA from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851167
|
|
165976854
|
APJL_1451 |
|
YP_001652447.1 |
galactose/methyl galaxtoside transporter ATP-binding protein |
Virulence factor |
MUTATION: mglA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
dksA from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851169
|
|
165975631
|
APJL_0176 |
|
YP_001651224.1 |
dosage-dependent DnaK suppressor protein |
Virulence factor |
MUTATION: dksA mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
dmsA from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851276
|
|
165977108
|
APJL_1705 |
|
YP_001652701.1 |
anaerobic dimethyl sulfoxide reductase chain A precursor |
Virulence factor |
MUTATION: dmsA mutant is attenuated in pigs [Ref6879:Baltes et al., 2003]. |
14638764
|
|
|
frpB from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851335
|
|
165975732
|
APJL_0286 |
|
YP_001651325.1 |
iron-regulated outer membrane protein |
Virulence factor |
MUTATION: frpB mutant is avirulent in pigs [Ref6878:Buettner et al., 2009]. |
19343711
|
|
|
yfeB |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851399
|
|
165975728
|
APJL_0280 |
CP000687 |
YP_001651321 |
iron (chelated) transporter, ATP-binding protein |
Virulence factor |
MUTATION: yfeB mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
lppB |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851473
|
|
165977377
|
APJL_1978 |
CP000687 |
YP_001652970 |
outer membrane antigenic lipoprotein B |
Virulence factor |
MUTATION: lppB mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
prfC from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851529
|
|
165975488
|
APJL_0031 |
|
YP_001651081.1 |
peptide chain release factor 3 |
Virulence factor |
MUTATION: prfC mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
hemE from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851531
|
|
165975568
|
APJL_0113 |
|
YP_001651161.1 |
uroporphyrinogen decarboxylase |
Virulence factor |
MUTATION: hemE mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
nqrA from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851670
|
|
165975606
|
APJL_0151 |
|
YP_001651199.1 |
Na(+)-translocating NADH-quinone reductase subunit A |
Virulence factor |
MUTATION: nqrA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
argG from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851696
|
|
165975881
|
APJL_0447 |
|
YP_001651474.1 |
argininosuccinate synthase |
Virulence factor |
MUTATION: argG mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
tig from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851732
|
|
165976936
|
APJL_1533 |
|
YP_001652529.1 |
trigger factor |
Virulence factor |
MUTATION: tig mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
fur from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851786
|
|
165976638
|
APJL_1231 |
|
YP_001652231.1 |
ferric uptake regulation protein |
Virulence factor |
MUTATION: fur mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
luxS from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851794
|
|
165976636
|
APJL_1229 |
|
YP_001652229.1 |
S-ribosylhomocysteinase |
Virulence factor |
MUTATION: luxS mutant is attenuated in mice [Ref6886:Li et al., 2008]. |
18585450
|
|
|
cpxD from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851863
|
|
165977018
|
APJL_1615 |
|
YP_001652611.1 |
HexD, capsule biosynthetic locus protein |
Virulence factor |
MUTATION: cpxD mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
corC from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851868
|
|
165975832
|
APJL_0390 |
|
YP_001651425.1 |
magnesium and cobalt efflux protein |
Virulence factor |
MUTATION: corC mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
cpxB from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851869
|
|
165977020
|
APJL_1617 |
|
YP_001652613.1 |
capsule polysaccharide export transport system permease protein |
Virulence factor |
MUTATION: cpxB mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
pnp from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851945
|
|
165975991
|
APJL_0570 |
|
YP_001651584.1 |
polynucleotide phosphorylase/polyadenylase |
Virulence factor |
MUTATION: pnp mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
cpxC from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851954
|
|
165977019
|
APJL_1616 |
|
YP_001652612.1 |
capsule polysaccharide export transport system permease protein |
Virulence factor |
MUTATION: cpxC mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
guaA from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5851973
|
|
165976006
|
APJL_0585 |
|
YP_001651599.1 |
GMP synthase |
Virulence factor |
MUTATION: guaA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
aroQ from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852036
|
|
165977306
|
APJL_1905 |
|
YP_001652899.1 |
3-dehydroquinate dehydratase |
Virulence factor |
MUTATION: aroQ mutant is attenuated in pigs [Ref6881:Ingham et al., 2002]. |
11731178
|
|
|
hemA from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852041
|
|
165975865
|
APJL_0425 |
|
YP_001651458.1 |
glutamyl-tRNA reductase |
Virulence factor |
MUTATION: hemA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
dsbA from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852086
|
|
165977312
|
APJL_1911 |
|
YP_001652905.1 |
thiol:disulfide interchange protein |
Virulence factor |
MUTATION: dsbA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
hgbA from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852221
|
|
165976472
|
APJL_1065 |
|
YP_001652065.1 |
hemoglobin and hemoglobin-haptoglobin-binding protein 4 precursor |
Virulence factor |
MUTATION: hgbA mutant is attenuated in pigs [Ref6882:Shakarji et al., 2006]. |
16699590
|
|
|
mrp from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852278
|
|
165976425
|
APJL_1018 |
|
YP_001652018.1 |
putative ATPase |
Virulence factor |
MUTATION: mrp mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
htpG from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852294
|
|
165976413
|
APJL_1004 |
|
YP_001652006.1 |
heat shock protein 90 |
Virulence factor |
MUTATION: htpG mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
irp from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852390
|
|
165976339
|
APJL_0930 |
|
YP_001651932.1 |
iron-regulated outer membrane protein |
Virulence factor |
MUTATION: irp mutant is attenuated in competitive index experiment in pig infection model [Ref6877:Subashchandrabose et al., 2009]. |
19703979
|
|
|
pntB from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852493
|
|
165976258
|
APJL_0849 |
|
YP_001651851.1 |
pyridine nucleotide transhydrogenase |
Virulence factor |
MUTATION: pntB mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
recR from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852506
|
|
165975531
|
APJL_0074 |
|
YP_001651124.1 |
recombination protein RecR |
Virulence factor |
MUTATION: recR mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
lpdA from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852591
|
|
165976188
|
APJL_0774 |
|
YP_001651781.1 |
dihydrolipoamide dehydrogenase |
Virulence factor |
MUTATION: lpdA mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
dnaK from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852606
|
|
165977352
|
APJL_1953 |
|
YP_001652945.1 |
molecular chaperone DnaK |
Virulence factor |
MUTATION: dnaK mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
ilvI from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852660
|
|
165976143
|
APJL_0729 |
|
YP_001651736.1 |
acetolactate synthase 3 catalytic subunit |
Virulence factor |
MUTATION: ilvI mutant is attenuated in pigs [Ref6877:Subashchandrabose et al., 2009]. |
19703979
|
|
|
aroA from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852699
|
|
165976117
|
APJL_0697 |
|
YP_001651710.1 |
3-phosphoshikimate 1-carboxyvinyltransferase |
Virulence factor |
MUTATION: aroA mutant is attenuated in pigs [Ref6876:Garside et al., 2002]. |
12027598
|
|
|
moaA from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852711
|
|
165976108
|
APJL_0688 |
|
YP_001651701.1 |
molybdenum cofactor biosynthesis protein A |
Virulence factor |
MUTATION: moaA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
dnaJ from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852738
|
|
165977351
|
APJL_1952 |
|
YP_001652944.1 |
chaperone protein DnaJ |
Virulence factor |
MUTATION: dnaJ mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
hlyX from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852761
|
|
165976066
|
APJL_0646 |
|
YP_001651659.1 |
fumarate/nitrate reduction transcriptional regulator |
Virulence factor |
MUTATION: hlyX mutant is attenuated in pigs [Ref6885:Baltes et al., 2005]. |
16040973
|
|
|
galU from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852767
|
|
165976061
|
APJL_0641 |
|
YP_001651654.1 |
UTP-glucose-1-phosphate uridylyltransferase |
Virulence factor |
MUTATION: galU mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
arcA from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852795
|
|
165975506
|
APJL_0049 |
|
YP_001651099.1 |
two-component response regulator |
Virulence factor |
MUTATION: arcA mutant is attenuated in pigs [Ref6887:Buettner et al., 2008]. |
17881160
|
|
|
atpG from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852826
|
|
165977083
|
APJL_1680 |
|
YP_001652676.1 |
F0F1 ATP synthase subunit gamma |
Virulence factor |
MUTATION: atpG mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
lon from Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
Actinobacillus pleuropneumoniae serovar 3 str. JL03 |
5852841
|
|
165975836
|
APJL_0394 |
|
YP_001651429.1 |
ATP-dependent protease LA |
Virulence factor |
MUTATION: lon mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
pntB from Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
6395887
|
|
190150167
|
APP7_0898 |
|
YP_001968692.1 |
pyridine nucleotide transhydrogenase |
Virulence factor |
MUTATION: pntB mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
moaA from Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
6396208
|
|
190150001
|
APP7_0732 |
|
YP_001968526.1 |
molybdenum cofactor biosynthesis protein A |
Virulence factor |
MUTATION: moaA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
guaA from Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
6396394
|
|
190149906
|
APP7_0637 |
|
YP_001968431.1 |
GMP synthase |
Virulence factor |
MUTATION: guaA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
hemA from Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
6396804
|
|
190149697
|
APP7_0428 |
|
YP_001968222.1 |
glutamyl-tRNA reductase |
Virulence factor |
MUTATION: hemA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
dnaK from Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
6397101
|
|
190151264
|
APP7_1995 |
|
YP_001969789.1 |
molecular chaperone DnaK |
Virulence factor |
MUTATION: dnaK mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
hemE from Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
6397393
|
|
190149381
|
APP7_0112 |
|
YP_001967906.1 |
uroporphyrinogen decarboxylase |
Virulence factor |
MUTATION: hemE mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
prfC from Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
6397642
|
|
190149299
|
APP7_0030 |
|
YP_001967824.1 |
peptide chain release factor 3 |
Virulence factor |
MUTATION: prfC mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
znuA from Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
6397685
|
|
190150761
|
APP7_1492 |
|
YP_001969286.1 |
high-affinity zinc transporter periplasmic component |
Virulence factor |
MUTATION: znuA mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
recR from Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
6397705
|
|
190149343
|
APP7_0074 |
|
YP_001967868.1 |
recombination protein RecR |
Virulence factor |
MUTATION: recR mutant is attenuated in pigs [Ref6874:Sheehan et al., 2003]. |
12819083
|
|
|
tig from Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
6397772
|
|
190150836
|
APP7_1567 |
|
YP_001969361.1 |
trigger factor |
Virulence factor |
MUTATION: tig mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
rpmF from Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
Actinobacillus pleuropneumoniae serovar 7 str. AP76 |
6397986
|
|
190150706
|
APP7_1437 |
|
YP_001969231.1 |
50S ribosomal protein L32 |
Virulence factor |
MUTATION: rpmF mutant is attenuated in porcine model of infection [Ref6875:Fuller et al., 2000]. |
10873489
|
|
|
LPS |
Actinobacillus pleuropneumoniae |
|
|
|
|
|
|
|
Virulence factor |
MUTATION: an isogenic LPS mutant (with a mutation in the galU gene) was attenuated in adherence and virulence in pigs [Ref7309:Rioux et al., 1999]. |
10696481
|
|
|
capsule |
Actinobacillus pleuropneumoniae |
|
|
|
|
|
|
|
Virulence factor |
MUTATION: an acapsular cpxC mutant is avirulent in pigs [Ref7310:Jacques, 2004]. |
15188950
|
|
|
apxIIA |
Actinobacillus pleuropneumoniae L20 |
4848738
|
|
126208432
|
APL_0956 |
CP000569 |
YP_001053657 |
RTX-II toxin determinant A |
Virulence factor |
MUTATION: A ΔapxIIA is attenuated in pigs [Ref7360:Boekema et al., 2004].
MUTATION: ureC/apxIIA deletion mutant is attenuated in pigs [Ref7359:Tonpitak et al., 2002].
|
15135509
12438394
|
|
|
apxIIC |
Actinobacillus pleuropneumoniae L25-4 |
|
|
52630373
|
|
AAU84699.1 |
|
ApxIIC |
Virulence factor |
MUTATION: An insertionally inactivated apxIIC mutant is attenuated in pigs [Ref7361:Prideaux et al., 1999]. |
10085043
|
|
|
apxIIIB |
Actinobacillus pleuropneumoniae serovar 2 |
|
470686
|
|
|
AAA21925.1 |
|
RTX toxin |
Virulence factor |
MUTATION: An apxIIIB mutant, in combination with an apxIIID mutation, is highly attenuated in pigs [Ref7362:Park et al., 2009]. |
19887737
|
|
|
apxIIID |
Actinobacillus pleuropneumoniae serovar 2 |
|
470687
|
|
|
|
AAA21926.1 |
RTX toxin |
Virulence factor |
MUTATION: An apxIIIB mutant, in combination with an apxIIID mutation, is highly attenuated in pigs [Ref7362:Park et al., 2009]. |
19887737
|
|
|
apxIVA |
Actinobacillus pleuropneumoniae |
|
|
6671152
|
|
AAF23114.1 |
|
ApxIVA |
Virulence factor |
MUTATION: A precisely defined DeltaapxIICDeltaapxIVA double-deletion mutant of A. pleuropneumoniae is attenuated in pigs [Ref7363:Liu et al., 2007]. |
17767980
|
|
|
ureC |
Actinobacillus pleuropneumoniae |
|
|
2828543
|
|
AAC00060.1 |
|
UreC |
Virulence factor |
MUTATION: ureC/apxIIA deletion mutant is attenuated in pigs [Ref7359:Tonpitak et al., 2002]. |
12438394
|
