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aroA from Actinobacillus pleuropneumoniae serovar 3 str. JL03

Victor ID 4145
Gene Name aroA from Actinobacillus pleuropneumoniae serovar 3 str. JL03
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae serovar 3 str. JL03
NCBI Gene ID 5852699
NCBI Protein GI 165976117
Locus Tag APJL_0697
Protein Accession YP_001651710.1
Other Database IDs UniProtKB-ID: AROA_ACTPJ
UniRef100: UniRef100_B3GXD4
UniRef90: UniRef90_A3N063
UniRef50: UniRef50_B1JXR9
UniParc: UPI00016372DF
EMBL: CP000687
EMBL-CDS: ABY69266.1
RefSeq_NT: NC_010278.1
GenomeReviews: CP000687_GR
KEGG: apj:APJL_0697
HOGENOM: HBG646626
OMA: GADIEWG
ProtClustDB: PRK02427
BioCyc: APLE434271:APJL_0697-MONOMER
Taxonomy ID 434271
Gene Starting Position 765659
Gene Ending Position 766957
Gene Strand (Orientation) -
Protein Name 3-phosphoshikimate 1-carboxyvinyltransferase
DNA Sequence 
>gi|165975457:765659-766957 Actinobacillus pleuropneumoniae serovar 3 str. JL03, complete genome
GTTATGTTCTTTCCGACAACTTCTCAAATTCGGTGAAATAAGTCGGGAAGGTTTTTGCCGTACATTTTGG
ATCTAAAATCGTCACCGGTGTATCAGACAATGCAATCAACGAAAAACACATCGCCATACGGTGATCATTA
TAAGTGGCAATTTCTGCATGTTGGAATTGTGTGAGTGGCAAAGGCTGAATGCGAATAAAATCTTCGCCTT
CCTCAACGGTTGCACCGACTTTACGCAATTCGGTCGCCATCGCCGTTAAACGATCGGTTTCTTTGACACG
CCAGTTATAAATATTGCGAATCACCGTTTCCCCTTCGGCAAATAATGCGGCGGTTGCAATCGTCATCGCT
GCATCCGGAATATGGTTCATATCCATATCCACACCTTTAAGCTTACCCTGTTCCGCTTGGATAAAATCGT
CACCCCAAGTGATTTTCGCGCCCATCGCTTCCAGCACATTGGCAAACAAGCGGTCGCCTTGGATCGAATT
TTTACCAATACCGGTTACCTTTACTTTACCTTTAATCGCACCGGCTGCTAAGAAATAAGAAGCGGATGAC
GCATCGCCTTCTACCAAATATTTTTCCGGTGAGAGATAACTTTGATTACCTTTAACCACAAAGGTCTGGT
AATTTCGATTCTCAACTTTTACTCCAAAATCTTTCATCATCGCCAAGGTAATATCAATATAAGGTTTTGA
TACCAGTTCACCGATAATTTCAATTTCCATATCGCCTTCGGCAAGCGGTGCCGCCATCAGTAAAGCGGTT
AAGAATTGGCTGGAAATTGAGCCGTCAATTTGTACTTTTCCGCCTTTTAGACCGCTATTGCGGATTGCTA
CTGGCGGATAACCTTCATTTTCCAAATATTGAACGCTTGCACCCGCTTGACGAAGGGCATCAACTAAGTG
TTTGATCGGGCGTTCTTTCATACGAGGCTCGCCGGTTAAAACCACTTCCGCTTCAGTTGCGCCTTTTAAA
CATAATGCTGCGGTTAACGGACGCATTGCCGTACCGGCATTACCTAAAAATAACGCCAAACCGTTTTTCC
AATTAAACGCACCGCCGACACCTTCAACGGTACAAACGGTTTTATCTTCCGATAATGAATAATTAACGCC
TAATGCTTTTAACGCATTGAGCATATGGCGAATATCGTCACTGTCTAATAAATTGGTAACCTTAGTCGTC
CCTTTCGCTAAAGCGGCTAATAATAACGCACGATTTGAAAGGCTTTTTGAGCCGGGTAAATTAATCTCGC
CCTCAACACGGCTGATCGGTGCTAATGTAATTTTTTCCA
Protein Sequence 
>gi|165976117|ref|YP_001651710.1| 3-phosphoshikimate 1-carboxyvinyltransferase [Actinobacillus pleuropneumoniae serovar 3 str. JL03] MEKITLAPISRVEGEINLPGSKSLSNRALLLAALAKGTTKVTNLLDSDDIRHMLNALKALGVNYSLSEDKTVCTVEGVGGAFNWKNGLALFLGNAGTAMRPLTAALCLKGATEAEVVLTGEPRMKERPIKHLVDALRQAGASVQYLENEGYPPVAIRNSGLKGGKVQIDGSISSQFLTALLMAAPLAEGDMEIEIIGELVSKPYIDITLAMMKDFGVKVENRNYQTFVVKGNQSYLSPEKYLVEGDASSASYFLAAGAIKGKVKVTGIGKNSIQGDRLFANVLEAMGAKITWGDDFIQAEQGKLKGVDMDMNHIPDAAMTIATAALFAEGETVIRNIYNWRVKETDRLTAMATELRKVGATVEEGEDFIRIQPLPLTQFQHAEIATYNDHRMAMCFSLIALSDTPVTILDPKCTAKTFPTYFTEFEKLSERT
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aroA mutant is attenuated in pigs (Garside et al., 2002).
COG COG0128E, under E: Amino acid transport and metabolism
References
Garside et al., 2002: Garside LH, Collins M, Langford PR, Rycroft AN. Actinobacillus pleuropneumoniae serotype 1 carrying the defined aroA mutation is fully avirulent in the pig. Research in veterinary science. 2002; 72(2); 163-167. [PubMed: 12027598].