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hemA from Actinobacillus pleuropneumoniae serovar 7 str. AP76

Victor ID 4175
Gene Name hemA from Actinobacillus pleuropneumoniae serovar 7 str. AP76
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae serovar 7 str. AP76
NCBI Gene ID 6396804
NCBI Protein GI 190149697
Locus Tag APP7_0428
Protein Accession YP_001968222.1
Other Database IDs UniProtKB-ID: HEM1_ACTP7
UniRef100: UniRef100_B3H0R8
UniRef90: UniRef90_A3MZC2
UniRef50: UniRef50_Q65SX9
UniParc: UPI00016373E9
EMBL: CP001091
EMBL-CDS: ACE61080.1
RefSeq_NT: NC_010939.1
GenomeReviews: CP001091_GR
KEGG: apa:APP7_0428
HOGENOM: HBG732626
OMA: GPILNRL
ProtClustDB: PRK00045
Taxonomy ID 537457
Gene Starting Position 488060
Gene Ending Position 489370
Gene Strand (Orientation) -
Protein Name glutamyl-tRNA reductase
DNA Sequence 
>gi|190149269:488060-489370 Actinobacillus pleuropneumoniae serovar 7 str. AP76, complete genome
ATTATTGTTCTTCTAATTTTAAGGCTTTAGAAAAACTCTGAAGTCCTTGAGAATTTCCGCTCTTCGCCAT
AGCCTGTAACGCTTGGGTCGGCACGTGTAATAAGCTGTTGGTCAGTTTATAACTTAGCTCGTTAAGGACT
TTTTCACTATCTTGTCCACTGGTTAAGGCAACTAATGCTTTCGCTAATAGCTCTTGACGAGTTTGCTCGG
CATCTTGGCGATAACGTTTAATCAAATCGCTGGATTGCTGTTGTTTCAGCCATTCAAAGAACGCTTTACA
TTCTTCATCCACAATTTGTGCCGCTTGTTCTGCAGCTTGTTCTCGTTGCGCCATATTACGTTGAATGATA
TGTTGTAAATCATCTACGCTGTAAGAATATACCGCATCCAATTCGCCGGCATTTTCGTCAATATCGCGAG
GAACGGCAATATCAATCAATAACATCGGATCAAACTGGCGTTGTTTCTGTGCGATTTCCACCATTTCTTT
GCTAATCAGCATATCCGGACTGCCGGTAGAACTGATAACGATATCCGCTTGGTTTAAACCGATTTGCAAT
GCGCTTAATGATAAAATTTGCATCGGCGTGTTTAAACGCTCCGCTAACGTTTCCGCACGTTGCGGCGTAC
GGTTGGCGATCATAATGTTTTTCGCGCCGTGCTGAATTAAATAACGCGCGACTAATTCGATGGTTTCGCC
GGCACCGACCAACAAGAAACGCAATTTACCGAAATTATCGAAAATCTGGCGTGCCAAACCGCAAGCGGCA
TAAGCGACCGATACCGCACTTGAACCGATTTCCGTTTCGGAACGCACACGTTTTGCCGTCGAAAAGGTAC
GTTGGAACAGACGGGATAATTTAGTAGAAATATGGCTGTTCTGCGATTGGTAAAAATTCTCGCTATATTG
ATAAGCTTGTTTTACCTGACCTAGAATTTGCGGCTCGCCCAAGATAAGCGAATCTAAACCGCACGCTACT
CGCATTAAATGACGAGCGGCTTCCATATTTTGTTTGAAATAAATACATTCGCGTAGTTCATTATGTTCAA
GTTGATGAATTTCGGCAAACCATTCAAAACATTGTTCACGCCATGCGATGTTATCTTCATGTTCTTCTCG
CGGCGTAATTTCCGCATTATGAAAATAAAGCTCTGTTCGGTTACACGTTGAAAGAATGACAACGCTTTCA
GCAAGTGCGCGGTGTTGAATTTGCTCAAAAGCAAGCTGACGTTTTTGATCATCAAACGCCACCTTACTTC
GCAAATTTACCGAGGCCGTTTTATGGTTAATACCAAGTGCTAAAATCGTCA
Protein Sequence 
>gi|190149697|ref|YP_001968222.1| glutamyl-tRNA reductase [Actinobacillus pleuropneumoniae serovar 7 str. AP76] MTILALGINHKTASVNLRSKVAFDDQKRQLAFEQIQHRALAESVVILSTCNRTELYFHNAEITPREEHEDNIAWREQCFEWFAEIHQLEHNELRECIYFKQNMEAARHLMRVACGLDSLILGEPQILGQVKQAYQYSENFYQSQNSHISTKLSRLFQRTFSTAKRVRSETEIGSSAVSVAYAACGLARQIFDNFGKLRFLLVGAGETIELVARYLIQHGAKNIMIANRTPQRAETLAERLNTPMQILSLSALQIGLNQADIVISSTGSPDMLISKEMVEIAQKQRQFDPMLLIDIAVPRDIDENAGELDAVYSYSVDDLQHIIQRNMAQREQAAEQAAQIVDEECKAFFEWLKQQQSSDLIKRYRQDAEQTRQELLAKALVALTSGQDSEKVLNELSYKLTNSLLHVPTQALQAMAKSGNSQGLQSFSKALKLEEQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hemA mutant is attenuated in pigs (Sheehan et al., 2003).
COG COG0373H, under H: Coenzyme transport and metabolism
References
Sheehan et al., 2003: Sheehan BJ, Bossé JT, Beddek AJ, Rycroft AN, Kroll JS, Langford PR. Identification of Actinobacillus pleuropneumoniae genes important for survival during infection in its natural host. Infection and immunity. 2003; 71(7); 3960-3970. [PubMed: 12819083].