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dnaK from Actinobacillus pleuropneumoniae serovar 7 str. AP76

Victor ID 4176
Gene Name dnaK from Actinobacillus pleuropneumoniae serovar 7 str. AP76
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae serovar 7 str. AP76
NCBI Gene ID 6397101
NCBI Protein GI 190151264
Locus Tag APP7_1995
Protein Accession YP_001969789.1
Other Database IDs UniProtKB-ID: DNAK_ACTP7
UniRef100: UniRef100_B3H2X7
UniRef90: UniRef90_Q4QJW4
UniRef50: UniRef50_P38646
UniParc: UPI0001761B37
EMBL: CP001091
EMBL-CDS: ACE62647.1
RefSeq_NT: NC_010939.1
GenomeReviews: CP001091_GR
KEGG: apa:APP7_1995
HOGENOM: HBG334976
OMA: KANNGDA
ProtClustDB: PRK00290
Taxonomy ID 537457
Gene Starting Position 2198064
Gene Ending Position 2199962
Gene Strand (Orientation) -
Protein Name molecular chaperone DnaK
DNA Sequence 
>gi|190149269:2198064-2199962 Actinobacillus pleuropneumoniae serovar 7 str. AP76, complete genome
ATTATTTATTATCTTTCACTTCTTCAAACTCAGCATCCACTACGCCGTCATCTTTTGCAGATTGTTGCGG
TTGTTCGCCTGCTTGTGCTTTAGCCTGAGCCGCTTGCATTAAAGGTTCGGACGCTTTGATTAACGCTTCA
GTTTTCGCATCGATTTCTGCTTTATCATCGCCTTTAGCCGCTTTTTCTAAGTCAGCGATAGCTGCTTCGA
TTTTCGCTTTATCATCTGCATTTAACGCATCACCAGCTTCTTCGATTTGTTTACGAGTTGCATGTGCGAT
ACCGTCCGCTTGGTTACGTGCTTGAACTAACTCTTCGAATTTTTTATCCGCTTCTGCGTTAGCTTCCGCA
TCACGAACCATTTTTTCGATTTCTTCGTCAGATAAACCTGAAGACGCTTGGATACGAATTTGTTGCTCTT
TACCTGTGTTTTTATCTTTCGCAGATACGTTAATTACACCGTTCGCATCGATATCGAAAGTTACTTCGAT
TTGCGGCATACCACGTGGTGCCGGGTTAATACCTTCAAGGTTGAATTGACCTAAAGATTTATTCGCAGAC
GCTTGTTTACGTTCACCTTGTAATACGTGGATTGTTACCGCTGATTGGTTGTCTTCCGCAGTTGAGAACA
CTTGTGATTTCTTGGTTGGAATCGTAGTGTTTTTCTCAATTAACACGGTCATCACGCCGCCCATAGTTTC
GATACCTAAAGATAATGGCGTAACGTCTAATAAAAGAACGTCTTTTACATCACCTTTTAATACACCACCT
TGAACCGCAGCACCGATTGCTACCGCTTCATCCGGGTTCACGTCTTTACGTGCTTCTTTACCGAAGAATT
CAGCCACTTTTTGTTGTACTAACGGCATACGTGTTTGACCACCAACGAGGATAATGTCGTTGATTTCATT
CACTGATTTACCTGCGTCTTTTAATACGGTTTTAAGTGACTCGATTGAGCTTGCAACTAAATCTTCTACT
AATGCTTCTAATTTCGCACGGGTTACGTTGATCGCTAAGTGTTTAGGACCTGTCGCATCCGCTGTGATAT
ACGGAAGATTTACTTCGGTAGATTGTGCTGAAGAAAGTTCGATTTTCGCTTTTTCCGCCGCTTCTTTAAC
ACGTTGTAATGCCATTGGGTCGTTGCGTAAATCCACGCCTTGTTCTTTTTTGAACTCGTCAATAATGTAG
TCGATTACACGGTTATCGAAGTCCTCACCACCTAAGTGAGTGTTACCGCCGGTTGCTAATACTTCGAATG
TTTGTTCGCCGTCGAAGTTATCGATTTCGATGATTGAGATATCGAATGTACCACCACCTAAGTCGTAAAC
GGCGATCACTTGGTTTTCTTTAGTTGAACCTAAACCGAACGCTAACGCTGCTGCTGTCGGTTCGTTGATG
ATACGTTTAACGTCTAAACCTGCGATACGACCTGCATCGATTGTCGCTTGACGTTGCGCATCGTTAAAGT
ATGCCGGTACAGTGATAACCGCTTCAGTTACCGCTTCGCCAAGGAAATCTTCCGCGGTTTTTTTCATTTT
TTTCAACACTTCTGCTGAAATTTGCGGTGGTGCTAACTTATCGCCTTTTACGTTTACCCATGCATCGCCG
TTGTCGGCACGTGTGATTTCGAAAGGCATAATTTTAATATCGCGTTGTACTTCTTCACTTTCAAAACGAC
GACCGATTAAACGTTTGATTGCAAATAATGTATTTTTCGGGTTTGTAATCGCCTGACGTTTTGCCGGTTG
ACCAACTAACGTTTCGTTATCCGTATAAGCAATGATTGACGGAGTTGTACGTGCGCCTTCCGCATTCTCG
ATTACACGTGCTTTGTCACCGTCCATTACCGCTACACAAGAGTTTGTTGTACCTAAGTCAATACCAATGA
TTTTACCCA
Protein Sequence 
>gi|190151264|ref|YP_001969789.1| chaperone protein DnaK [Actinobacillus pleuropneumoniae serovar 7 str. AP76] MGKIIGIDLGTTNSCVAVMDGDKARVIENAEGARTTPSIIAYTDNETLVGQPAKRQAITNPKNTLFAIKRLIGRRFESEEVQRDIKIMPFEITRADNGDAWVNVKGDKLAPPQISAEVLKKMKKTAEDFLGEAVTEAVITVPAYFNDAQRQATIDAGRIAGLDVKRIINEPTAAALAFGLGSTKENQVIAVYDLGGGTFDISIIEIDNFDGEQTFEVLATGGNTHLGGEDFDNRVIDYIIDEFKKEQGVDLRNDPMALQRVKEAAEKAKIELSSAQSTEVNLPYITADATGPKHLAINVTRAKLEALVEDLVASSIESLKTVLKDAGKSVNEINDIILVGGQTRMPLVQQKVAEFFGKEARKDVNPDEAVAIGAAVQGGVLKGDVKDVLLLDVTPLSLGIETMGGVMTVLIEKNTTIPTKKSQVFSTAEDNQSAVTIHVLQGERKQASANKSLGQFNLEGINPAPRGMPQIEVTFDIDANGVINVSAKDKNTGKEQQIRIQASSGLSDEEIEKMVRDAEANAEADKKFEELVQARNQADGIAHATRKQIEEAGDALNADDKAKIEAAIADLEKAAKGDDKAEIDAKTEALIKASEPLMQAAQAKAQAGEQPQQSAKDDGVVDAEFEEVKDNK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dnaK mutant is attenuated in porcine model of infection (Fuller et al., 2000).
COG COG0443O, under O: Posttranslational modification, protein turnover, chaperones
References
Fuller et al., 2000: Fuller TE, Martin S, Teel JF, Alaniz GR, Kennedy MJ, Lowery DE. Identification of Actinobacillus pleuropneumoniae virulence genes using signature-tagged mutagenesis in a swine infection model. Microbial pathogenesis. 2000; 29(1); 39-51. [PubMed: 10873489].