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frpB from Actinobacillus pleuropneumoniae serovar 3 str. JL03

Victor ID 4117
Gene Name frpB from Actinobacillus pleuropneumoniae serovar 3 str. JL03
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae serovar 3 str. JL03
NCBI Gene ID 5851335
NCBI Protein GI 165975732
Locus Tag APJL_0286
Protein Accession YP_001651325.1
Other Database IDs UniProtKB-ID: B0BT24_ACTPJ
UniRef100: UniRef100_A3MYZ8
UniRef90: UniRef90_A3MYZ8
UniRef50: UniRef50_A3MYZ8
UniParc: UPI00003978CA
EMBL: CP000687
EMBL-CDS: ABY68881.1
RefSeq_NT: NC_010278.1
GenomeReviews: CP000687_GR
KEGG: apj:APJL_0286
HOGENOM: HBG296623
OMA: KANGNIY
ProtClustDB: CLSK878324
BioCyc: APLE434271:APJL_0286-MONOMER
Taxonomy ID 434271
Gene Starting Position 305803
Gene Ending Position 307773
Gene Strand (Orientation) +
Protein Name iron-regulated outer membrane protein
DNA Sequence 
>gi|165975457:305803-307773 Actinobacillus pleuropneumoniae serovar 3 str. JL03, complete genome
AATGCATAAAAAAACAATATTTAAATTAAGCTTAATTAGTTTAGCCGTCGCCGGCTATGCGGAAGCTAAT
CAAGCTACACTTGATACGGTGAAGGTTCAAGCTCAACCTACGGTGAATCATACTAGAAATATCAGTAACC
TGCGCGAATTACTGGCTAATCGTACGGACATTAACGTCGGTGGAGGTAGCGTGTCCGCACAATACATTTC
GATTCGCGGATCAGGACAAGATCGTATCGGTATGATTGTCGATAATACTTCGACAAATACTCAACAGTGG
TATCACCAAGGTCGTTTCCAACTGGATCCGTCTATGGTGAAATCGATTAAAATCGATAAGGGCGCCGGTT
CCGCCAGTGCCGGTATCGGTATAACGGACGGTGTAATCCGTGCGGAAACGGTATCGGCAAAAGATTTATT
GAAAGACGGCAGATCATTCGGTGCGCGTATCGGTTCCGAATATAACAGTAATCGCGGCATTAACGATTCG
CTTTCACTCTATGGACAAGCGAATAATCTGGATGTATTGCTATTAGGCAGTTGGGGAGACGATAAAAACT
ATAAGGCGGGTAAAGGTTATTCGGATGCGGTGAATAAAAATAGCCGAGTAGTGAATAATACCGCTCGTCG
TCAAGGTAATTATTTGGCGAAATTCGGCTATGATATTACCGATAAACAGCGTATCGGCTTAAGTTTCCGT
CAAGAGTCGTTTTATGGTGCGGGACAAGATCGTTTCGAGATGATTTTTAATAGCCGCCCGGTAAATGCGA
ACACGACCAAACGTACCTACAACCTTGAGTATGATGCGAAAGACATCGGCTTTGCTCGAGACGTTAAAGC
GAATGTGTTCCATATTTTAGGGACGGATAAGCGAGAAGATTATCAGCAAAATAAATTAACCGGTTATCAA
CGTAGTTCTAAAACCAAAACAACGGGGGCTAATTTAGGCTTTACCAGCGAATTTGGCGGAGAGCATCTGT
TTAAATATGGTGTGAATCTGCGTAAAGAGCAGACAGGTAGTCAGAATTCGTTCGGCAATATTAAAGGCGA
ACAAAAATTCGAATACGGATTATATGCCGAAGGGATTTGGTCTTTAGGTAAAGTGCTGACCTTAACCACA
GGGTTACGTTATGATTACTATGATTTGGATACGGCTGGTAAAGTGGATAAAAACGGTAAACCGCTTGCCG
GTAATAAATCGGTATCCGATAAAAGATTAAATCCGAGTTTCGGATTGATTTGGGACATTACACCGAATTT
TGCTTTGAATGCTAAATTAAATTATGCAAGTCGCAGCCCTATTTTAGCTTCGGCAAATACCATAACCGAT
AACCGCGGTTCATTAGATAAAGCCAGAGGCTTACGTTTTATCGATCCTAAATTGAAAACCGAAGACGTAC
GTTTGGCGGAAGTCGGTTTTGAATGGAAATATGCCGATTTTAATTTAAAAGGCAGCGTGTTCGAGCAAAG
AGTTAAAAACTTCTATCAAACGACCAACAGTATCATTAGCAATGCGGGAACCTTAAAAACGAAAGGTTAT
GAAGCCGAGTTGGATTATCAATGGAACGCATTAAAATTAACCGCCGGTGTGGCGTATGCCGATCCGAAAG
CGGACTTTGCGCTTTCTAATGATCCGCTGAATGTTATTCCGCAAGGTCGTCAATGGAGTACCGGTGTTTC
GTATAAATTTGTTGAACCGAATTTAGAGATCGGTTGGTTAGGTCGCTATGCTCAGTCTAAAGAGTATAAA
ACGGGCGCTGCGCCGAAAGTCGAAACGAGAAGACGTATCGGATACGGCGTACATGATATTTTCGTAAACT
GGCAGCCGCTTAATCAAGACAACTTCAATGTGAATTTCACGGTAAAAAACATCGGTAATAAATTCTATCG
TAGTCACAGCCAAAGAAATCTTGAAGTCACGCCGCCAAGCCCGGGACGTGAGTTTAAAATCGGTATGAAC
TATAGTTTCTA
Protein Sequence 
>gi|165975732|ref|YP_001651325.1| iron-regulated outer membrane protein [Actinobacillus pleuropneumoniae serovar 3 str. JL03] MHKKTIFKLSLISLAVAGYAEANQATLDTVKVQAQPTVNHTRNISNLRELLANRTDINVGGGSVSAQYISIRGSGQDRIGMIVDNTSTNTQQWYHQGRFQLDPSMVKSIKIDKGAGSASAGIGITDGVIRAETVSAKDLLKDGRSFGARIGSEYNSNRGINDSLSLYGQANNLDVLLLGSWGDDKNYKAGKGYSDAVNKNSRVVNNTARRQGNYLAKFGYDITDKQRIGLSFRQESFYGAGQDRFEMIFNSRPVNANTTKRTYNLEYDAKDIGFARDVKANVFHILGTDKREDYQQNKLTGYQRSSKTKTTGANLGFTSEFGGEHLFKYGVNLRKEQTGSQNSFGNIKGEQKFEYGLYAEGIWSLGKVLTLTTGLRYDYYDLDTAGKVDKNGKPLAGNKSVSDKRLNPSFGLIWDITPNFALNAKLNYASRSPILASANTITDNRGSLDKARGLRFIDPKLKTEDVRLAEVGFEWKYADFNLKGSVFEQRVKNFYQTTNSIISNAGTLKTKGYEAELDYQWNALKLTAGVAYADPKADFALSNDPLNVIPQGRQWSTGVSYKFVEPNLEIGWLGRYAQSKEYKTGAAPKVETRRRIGYGVHDIFVNWQPLNQDNFNVNFTVKNIGNKFYRSHSQRNLEVTPPSPGREFKIGMNYSF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: frpB mutant is avirulent in pigs (Buettner et al., 2009).
COG COG1629P, under P: Inorganic ion transport and metabolism
References
Buettner et al., 2009: Buettner FF, Bendalla IM, Bossé JT, Meens J, Nash JH, Härtig E, Langford PR, Gerlach GF. Analysis of the Actinobacillus pleuropneumoniae HlyX (FNR) regulon and identification of iron-regulated protein B as an essential virulence factor. Proteomics. 2009; 9(9); 2383-2398. [PubMed: 19343711].