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fkpA

Victor ID 4052
Gene Name fkpA
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae L20
NCBI Gene ID 4849158
NCBI Protein GI 126209104
Locus Tag APL_1640
Genbank Accession CP000569
Protein Accession YP_001054329
Other Database IDs UniProtKB-ID: A3N2T8_ACTP2
UniRef100: UniRef100_A3N2T8
UniRef90: UniRef90_A3N2T8
UniRef50: UniRef50_A3N2T8
UniParc: UPI000039781A
EMBL: CP000569
EMBL-CDS: ABN74724.1
RefSeq_NT: NC_009053.1
GenomeReviews: CP000569_GR
KEGG: apl:APL_1640
eggNOG: COG0545
HOGENOM: HBG731200
OMA: SACNKEE
ProtClustDB: CLSK918997
BioCyc: APLE416269:APL_1640-MONOMER
Taxonomy ID 416269
Gene Starting Position 1864838
Gene Ending Position 1865569
Gene Strand (Orientation) +
Protein Name putative FKBP-type peptidyl-prolyl cis-trans isomerase
Protein pI 7.49
Protein Weight 25006.8
Protein Length 243
Protein Note 5.2.1.8
DNA Sequence 
>gi|126207488:1864838-1865569 Actinobacillus pleuropneumoniae L20, complete genome
TATGTTAAAAAATAAACTTTCTGTTCTTGCAATCGTAGCCGGTACGTTCGTTTCAGCTCAAACTGCATTT
GCAGCGGAACAAAAAGCGGATCAAAAATTCATTGACGATTCATCATATGCAGTCGGCGTATTGATGGGTA
AAAATATCGAAGGCGTCGTTGAATCACAAAAAGAAATTTTTTCTTATAACCAAGATAAAATCTTGGCGGG
TGTCCAAGATACCATCAAAAAAACCGGTAAATTAACCGATGAAGATCTACAAAAACAATTAAAATCGCTT
GATACTTATCTTGCAAGCCAAGAAAGCAAAATTGCGGCGGAGAAAAGCAAAGCAACCGTAGAAGCCGGTA
ATAAATTTCGTGCCGACTACGAAAAACAAAGCGGCGTGAAAAAAACCGCTTCCGGTTTACTTTATAAAAT
TGAAAAAGCCGGCACGGGCGAATCGCCTAAAGCGGAAGATACCGTTAAAGTTCACTATAAAGGGACATTA
ACCGATGGTACGGTATTCGATAGCTCATACGATCGCGGTGAGCCGATTGAATTCCAATTAAACCAATTAA
TTCCGGGTTGGATTGAAGCGATTCCAATGTTGAAAAAAGGCGGAAAAATGGAAATCGTCGTTCCGCCTGA
ACTTGGTTACGGCGAACGCCAAGCAGGTAAGATTCCGGCAAGTTCAACCTTAAAATTCGAGATTGAATTG
TTAGATTTCAAAGCGGCCGAAGCGAAAAAATA
Protein Sequence 
>gi|126209104|ref|YP_001054329.1| putative FKBP-type peptidyl-prolyl cis-trans isomerase [Actinobacillus pleuropneumoniae L20]
MLKNKLSVLAIVAGTFVSAQTAFAAEQKADQKFIDDSSYAVGVLMGKNIEGVVESQKEIFSYNQDKILAG
VQDTIKKTGKLTDEDLQKQLKSLDTYLASQESKIAAEKSKATVEAGNKFRADYEKQSGVKKTASGLLYKI
EKAGTGESPKAEDTVKVHYKGTLTDGTVFDSSYDRGEPIEFQLNQLIPGWIEAIPMLKKGGKMEIVVPPE
LGYGERQAGKIPASSTLKFEIELLDFKAAEAKK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: fkpA mutant is attenuated in porcine model of infection (Fuller et al., 2000).
COG COG0545O, under O: Posttranslational modification, protein turnover, chaperones
References
Fuller et al., 2000: Fuller TE, Martin S, Teel JF, Alaniz GR, Kennedy MJ, Lowery DE. Identification of Actinobacillus pleuropneumoniae virulence genes using signature-tagged mutagenesis in a swine infection model. Microbial pathogenesis. 2000; 29(1); 39-51. [PubMed: 10873489].