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dmsA from Actinobacillus pleuropneumoniae L20

Victor ID 4054
Gene Name dmsA from Actinobacillus pleuropneumoniae L20
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae L20
NCBI Gene ID 4849184
NCBI Protein GI 126209138
Locus Tag APL_1674
Protein Accession YP_001054363.1
Other Database IDs UniProtKB-ID: A3N2X2_ACTP2
UniRef100: UniRef100_A3N2X2
UniRef90: UniRef90_A3N2X2
UniRef50: UniRef50_B3H2R9
UniParc: UPI0000F284DE
EMBL: CP000569
EMBL-CDS: ABN74758.1
RefSeq_NT: NC_009053.1
GenomeReviews: CP000569_GR
KEGG: apl:APL_1674
eggNOG: COG0243
HOGENOM: HBG304064
OMA: FRQQGIF
ProtClustDB: CLSK870600
BioCyc: APLE416269:APL_1674-MONOMER
Taxonomy ID 416269
Gene Starting Position 1900091
Gene Ending Position 1902508
Gene Strand (Orientation) +
Protein Name anaerobic dimethyl sulfoxide reductase chain A precursor
DNA Sequence 
>gi|126207488:1900091-1902508 Actinobacillus pleuropneumoniae L20, complete genome
TATGTCAATTACAAGACGTGGATTCCTAAAAGGAACATCAGCAAGTATGACCGCATTAGCGGCATCCGGC
GGTATCGCTCTCCCTTTTGTTGCTAAAGCTGAAACAAAAGATAATGTTGCCGGACAAGCACAAGATGAAA
AAGTAGTTTGGAGTGCCTGTACAGTAAACTGTGGTAGCCGTTGTCCATTGAGAATGCATGTAAAAGATAA
TCAAATTTTATATGTGGAAACGGATAATACCGGTACGGAAACCTATAATCTTGATCATCAAGTTCGTGCT
TGTTTACGTGGGCGTTCAATGCGCCGTCGTGTTTATAATCCTGATCGTTTGAAATATCCGATGAAACGTG
TAGGTAAGCGTGGCGAGGGTAAATTTAAACGTATTTCTTGGGATGAAGCATTAACGGAAATTGCACAATC
ATTACGTAAAAATATTGAGAAATACGGTAATGAAAGTATTTATCTCAACTATGGTACGGGAACATTAGGT
GGAACCGTAACAAAATCTTGGCCGCCGGGTTCAACTTTAGTTGCACGTTTGATGAATTGTATCGGTGGTT
ATTTAAATCATTATGGCGACTATAGTACCGCTCAAATTGCAGTAGGTTTAGATTACACCTATGGTGGTGG
CTGGGCATTAGGCAATGGCTTAGCTGATATTGAAAACACAAAACTTATCGTACTATTCGGTAATAATCCA
GCGGAAACTCGCATGAGTGGAGGTGGTTTAACCTATTGTTTTGAGCAGGCTAAAGAAAAATCAAATGCCA
AAGTTATCATCATTGATCCACGTTATACGGATACAGGAGTGGGTAAAGAGGATGAATGGATTCCTATTCG
CCCTAGTACTGATGCAGCGTTAGTATCTGCACTTGCTTATGTATTAATCACCGAAAATATGGTCGATCAG
GCGTTTTTAGATAAATATTGTGTTGGCTATGATGAAAAAACATTACCTGCTGATGCACCTAAAAATGGTC
ATTATAAAGCCTATATTTTAGGTCAAGGCGATGATGGCATTGCTAAAACACCTGAATGGGCTTCTAAAAT
TACCGGTATTCCTGTTGAGCGTATTATCAAATTAGCCCGTGAAATTGGTCAAACAAAACCTGCTTATATT
TCACAAGGCTGGGGACCACAACGCCGTAGTAATGGCGAGTTAATTTCTCGTGCGATTGCGATGTTACCGA
TTTTAACCGGCAATGTAGGGATTAGTGGCGGTAATACAGGTGCAAGAGAAAGTGCTTATGGAATACCGTT
TGTAAGAATGCCAACTTTAACCAACCCGGTGCAAGCAAGTATCCCAATGTTCTTATGGACGGATGCGATT
CTTCGTGGTCCAGAGATGACCGCAACCACAGACGGCATTCAAGGTGTTGAAAAATTATCCGCACCAATTA
AAGTAATTTGGAATTATGCAAGTAACTGTTTGATTAACCAACATGCAGAAATTAACCGCACTCATGAAAT
TCTACAAGATGAGTCTAAATGTGAATTGATCATTACCATTGATAACCATATGACTTCAACTGCGAAATAT
AGTGATATTTTGTTACCGGATTGTATGACTTCAGAACAGATGGATTTCTGTTTAGATGCTTATGTTGCCA
ATATGAACTATGTTATTTTTGCTGATCAAGTGGTTAAACCTTCATTTGAGTGTCGTAATATCTACGATAT
GTTAAGTGATTTGGCTGAAAAATTAGGTGTAAAAGAACAATTTACGGAAGGCAGAACCCAAGAACAATGG
TTACGCCATATTTATGAGCAATCTCGCCAAAAATTACCTGAGCTTCCAACGTTTGAAGAATTTAGACAAC
AAGGTATTTTCAAAAAAGTCGATCCAAAAGGTTTCTTTATCGCTTATAAAGATTTCAGAGAAAACCCTGA
AGCGAATCCATTAAAAACACCGTCAGGTAAAATTGAAATCTATTCATCTCGTTTAGCGGAAATTGCACGT
ACTTGGAAATTGGAAAAAGATGAAGTGATTCATCCGTTACCAATTCATACCGATAGCTTTGAGCATTACG
GCGACCCATTAATGCAAAAATATCCGTTACAACTTTCCGGTTTCCATTATAAAGCGCGTACTCACTCAAC
TTACGGTAATGTTGATGTGATTAAAGAAGCTAATCCTCAAGAGATTTGGATTAATCCGATTGATGCACAA
ACGAGAGGAATTCAAAACGGGGAATTGGTTCGTATCTTTAATGATCGTGGGGAAGTGCGTATTAATGCTA
AGGTTACACCTCGTATTATTCCGGGTGTTGTAGCATTGAGTGAAGGGGCTTGGTATGCACCGGATAAAAA
TGGTGTGGATTATTCAGGTTGTATTAATGTGCTTACTACCCAACGCCCATCTCCACTAGCGAAAGGCAAT
CCGCAACATTCTAACTTAGTGCAAATTGAGAAATTATA
Protein Sequence 
>gi|126209138|ref|YP_001054363.1| anaerobic dimethyl sulfoxide reductase subunit A [Actinobacillus pleuropneumoniae serovar 5b str. L20] MSITRRGFLKGTSASMTALAASGGIALPFVAKAETKDNVAGQAQDEKVVWSACTVNCGSRCPLRMHVKDNQILYVETDNTGTETYNLDHQVRACLRGRSMRRRVYNPDRLKYPMKRVGKRGEGKFKRISWDEALTEIAQSLRKNIEKYGNESIYLNYGTGTLGGTVTKSWPPGSTLVARLMNCIGGYLNHYGDYSTAQIAVGLDYTYGGGWALGNGLADIENTKLIVLFGNNPAETRMSGGGLTYCFEQAKEKSNAKVIIIDPRYTDTGVGKEDEWIPIRPSTDAALVSALAYVLITENMVDQAFLDKYCVGYDEKTLPADAPKNGHYKAYILGQGDDGIAKTPEWASKITGIPVERIIKLAREIGQTKPAYISQGWGPQRRSNGELISRAIAMLPILTGNVGISGGNTGARESAYGIPFVRMPTLTNPVQASIPMFLWTDAILRGPEMTATTDGIQGVEKLSAPIKVIWNYASNCLINQHAEINRTHEILQDESKCELIITIDNHMTSTAKYSDILLPDCMTSEQMDFCLDAYVANMNYVIFADQVVKPSFECRNIYDMLSDLAEKLGVKEQFTEGRTQEQWLRHIYEQSRQKLPELPTFEEFRQQGIFKKVDPKGFFIAYKDFRENPEANPLKTPSGKIEIYSSRLAEIARTWKLEKDEVIHPLPIHTDSFEHYGDPLMQKYPLQLSGFHYKARTHSTYGNVDVIKEANPQEIWINPIDAQTRGIQNGELVRIFNDRGEVRINAKVTPRIIPGVVALSEGAWYAPDKNGVDYSGCINVLTTQRPSPLAKGNPQHSNLVQIEKL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dmsA mutant is attenuated in pigs (Baltes et al., 2003).
COG COG0243C, under C: Energy production and conversion
References
Baltes et al., 2003: Baltes N, Hennig-Pauka I, Jacobsen I, Gruber AD, Gerlach GF. Identification of dimethyl sulfoxide reductase in Actinobacillus pleuropneumoniae and its role in infection. Infection and immunity. 2003; 71(12); 6784-6792. [PubMed: 14638764].