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pnp from Actinobacillus pleuropneumoniae serovar 3 str. JL03

Victor ID 4130
Gene Name pnp from Actinobacillus pleuropneumoniae serovar 3 str. JL03
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae serovar 3 str. JL03
NCBI Gene ID 5851945
NCBI Protein GI 165975991
Locus Tag APJL_0570
Protein Accession YP_001651584.1
Other Database IDs UniProtKB-ID: PNP_ACTPJ
UniRef100: UniRef100_B0BUD5
UniRef90: UniRef90_A3MZU3
UniRef50: UniRef50_A1UU54
UniParc: UPI0001637600
EMBL: CP000687
EMBL-CDS: ABY69140.1
RefSeq_NT: NC_010278.1
GenomeReviews: CP000687_GR
KEGG: apj:APJL_0570
HOGENOM: HBG382411
OMA: YGETVVL
ProtClustDB: PRK11824
BioCyc: APLE434271:APJL_0570-MONOMER
Taxonomy ID 434271
Gene Starting Position 610765
Gene Ending Position 612912
Gene Strand (Orientation) -
Protein Name polynucleotide phosphorylase/polyadenylase
DNA Sequence 
>gi|165975457:610765-612912 Actinobacillus pleuropneumoniae serovar 3 str. JL03, complete genome
TTTAAATCTCAGCTTGTTGTTCTGACGAAACTTCCGCTTCTTCAGTTACATTTTCGGCAACAGGGGTATC
GTTATTAAGATCTTTCATAGTTAAACGGATACGGTTTTGACGATCGATTTCAACTACTTTCACAGTCACT
TCTTGACCTACGGATAAGTAATCCGCAACGCGTTCGACACGCTCATTCGTGATTTGCGAAATATGTACTA
AACCTTCTTTACCACCTAAGATAGAAACGAACGCACCGAAGTCCACAACGCGAGTTACTTTACCTTTGTA
GATCGCGTTCACTTCAACTTCAGCCACGATATCTTCGATACGAGCCATTACCGCTTTCGCCGCATTATTA
TCGGTTGCGGCGATTTTTACGGTACCGTCGTCATCAATATCAATCGAAGTACCGGTTTCTTCGGTTAATG
CGCGAATTACCGCACCGCCTTTACCGATCACGTCTTTGATTTTCTTCGGATCGATCTTCATCGTATGAAT
ACGAGGTGCAAAATCGGAAATATCGGCACGAGGTGCAGGAATCGCTTGTTCCATCACGCTTAAGATGTGC
ATACGCGCACCTTTCGCTTGATTTAATGCGATTTGCATAATTTCAGGCGTGATACCTTCGATTTTAATAT
CCATTTGAAGTGCGGTTACACCTTCACGCGTACCGGCTACTTTGAAGTCCATATCGCCTAAATGGTCTTC
GTCACCTAAGATGTCTGAAAGTACCACAAATTTTTCTTCTTCTTTCACTAAGCCCATTGCGATACCCGCA
ACCGCCGCTTTAATCGGTACGCCTGCGTCCATTAACGCTAAAGATGCGCCGCATACGGAAGCCATTGAAG
AAGAACCGTTTGATTCGGTAATTTCAGATACTACGCGCACTACATACGGGAATTCTTCCGCAGTCGGCAT
TACCGCTAATACACCGCGTTTCGCTAAACGACCGTGGCCGATTTCACGACGTTTCGGCGAACCGATACGA
CCCGTTTCACCGACAGAGTACGGAGGGAAGTTATAGTGGAATAAGAAACGGTCTGATTTCTCGCCGGTTA
ATTCGTCAATAATTTGCGCATCGCGTTCGGTACCTAAAGTCGCAACCGCTAAGGCTTGCGTTTCACCGCG
AGTAAAGATTGCGGAACCGTGCGTACGAGGTAATACGCCGGTGCAAATGTCTAATGCGCGAACGGTATCT
ACCGTACGACCGTCAATACGCGGCTCGCCGGCAATGATACGACCGCGAACAATAGAACTTTCTAATGCGG
TAATAATATCAATAATCGCACCTTCCGAAATAGTTTCGTCTTGTGTGGTCAATTGTGCGATAACATCCGC
TTTAATTGCATCGATTTGTTCGTAACGCGCTTGTTTTTCCGTAATACGATATGCATCGCCGATACGCGCT
TCCGCTAACGCTTTAACTTGGTTGATTAATGCGGTATTCGGTTCCGGCGCAACCCAATCCCAACGCGGTT
TACCCGCTTCTTTTACGAATTCTTTAATATTTTCAATTACAACTTGTTGTTGCTGATGACCGAATACGAC
TGCGGATAACATTTGTTCTTCAGAAAGAATATCCGCTTCCGATTCAACCATTAATACCGCTTTATCCGTC
CCTGCTACTACAAGGTCTAAGCGGCTGATTTTTTGTTCTGAAGTGGTCGGGTTTAATACGAATTGATCAT
TGATAAAACCGACACGCGCCGCACCGATAGGACCGTTGAACGGTACGCCTGATAATGAAAGCGCCGCTGA
AGCACCGATCATCGCCACTAAATCCGGGCTGATTTGCGGGTTCACCGAAACAACCGTAGCAATCACTTGA
ATTTCGTTAAAGAAACCTTCCGGGAAAAGCGGGCGCACAGGGCGGTCAATTAAGCGAGCGATTAAGGTTT
CGCCTTCAGACGGACGACCTTCACGTTTGAAGAAACCGCCGGGAATACGACCGGCTGCATAAGTACGCTC
TTGATAATCTACCGTTAATGGGAAGAAATCTTGACCTTCTTTAACCTCTTTTTTAGCCACAACGGTGACG
AATACGGTAGTATCGTCCATGCTTGCCATAACGGCTGCCGTTGCTTGACGTGCGATAGCACCTGTTTCTA
ACGTTACGGTATGCTGACCGTATTTAAATTGCTTAACAATTGGATTCA
Protein Sequence 
>gi|165975991|ref|YP_001651584.1| polynucleotide phosphorylase/polyadenylase [Actinobacillus pleuropneumoniae serovar 3 str. JL03] MNPIVKQFKYGQHTVTLETGAIARQATAAVMASMDDTTVFVTVVAKKEVKEGQDFFPLTVDYQERTYAAGRIPGGFFKREGRPSEGETLIARLIDRPVRPLFPEGFFNEIQVIATVVSVNPQISPDLVAMIGASAALSLSGVPFNGPIGAARVGFINDQFVLNPTTSEQKISRLDLVVAGTDKAVLMVESEADILSEEQMLSAVVFGHQQQQVVIENIKEFVKEAGKPRWDWVAPEPNTALINQVKALAEARIGDAYRITEKQARYEQIDAIKADVIAQLTTQDETISEGAIIDIITALESSIVRGRIIAGEPRIDGRTVDTVRALDICTGVLPRTHGSAIFTRGETQALAVATLGTERDAQIIDELTGEKSDRFLFHYNFPPYSVGETGRIGSPKRREIGHGRLAKRGVLAVMPTAEEFPYVVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEEEKFVVLSDILGDEDHLGDMDFKVAGTREGVTALQMDIKIEGITPEIMQIALNQAKGARMHILSVMEQAIPAPRADISDFAPRIHTMKIDPKKIKDVIGKGGAVIRALTEETGTSIDIDDDGTVKIAATDNNAAKAVMARIEDIVAEVEVNAIYKGKVTRVVDFGAFVSILGGKEGLVHISQITNERVERVADYLSVGQEVTVKVVEIDRQNRIRLTMKDLNNDTPVAENVTEEAEVSSEQQAEI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pnp mutant is attenuated in porcine model of infection (Fuller et al., 2000).
COG COG1185J, under J: Translation, ribosomal structure and biogenesis
References
Fuller et al., 2000: Fuller TE, Martin S, Teel JF, Alaniz GR, Kennedy MJ, Lowery DE. Identification of Actinobacillus pleuropneumoniae virulence genes using signature-tagged mutagenesis in a swine infection model. Microbial pathogenesis. 2000; 29(1); 39-51. [PubMed: 10873489].