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lpdA from Actinobacillus pleuropneumoniae serovar 3 str. JL03

Victor ID 4142
Gene Name lpdA from Actinobacillus pleuropneumoniae serovar 3 str. JL03
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae serovar 3 str. JL03
NCBI Gene ID 5852591
NCBI Protein GI 165976188
Locus Tag APJL_0774
Protein Accession YP_001651781.1
Other Database IDs UniProtKB-ID: B0BP52_ACTPJ
UniRef100: UniRef100_B0BP52
UniRef90: UniRef90_P43784
UniRef50: UniRef50_P0A9P2
UniParc: UPI0001637452
EMBL: CP000687
EMBL-CDS: ABY69337.1
RefSeq_NT: NC_010278.1
GenomeReviews: CP000687_GR
KEGG: apj:APJL_0774
HOGENOM: HBG515043
OMA: TLGEAIM
ProtClustDB: PRK06467
BioCyc: APLE434271:APJL_0774-MONOMER
Taxonomy ID 434271
Gene Starting Position 847457
Gene Ending Position 848881
Gene Strand (Orientation) -
Protein Name dihydrolipoamide dehydrogenase
DNA Sequence 
>gi|165975457:847457-848881 Actinobacillus pleuropneumoniae serovar 3 str. JL03, complete genome
ATTAACGTTTTTTCGCTTTTGCGTTTGGTAAGTCCGTGATAGAACCTTCAAACACTTCCGCAGCTAAACC
TACCGATTCGTGTAATGTAGGGTGAGCATGGATAGTTAAAGCGATATCTTCCGCATCGCAACCCATTTCG
ATTGCAAGACCGATTTCACCTAATAATTCACCGCCGTTGCTACCTACGATTGCACCGCCAAGTAAACGGT
GAGTATCTTTATCGAAGATAAGTTTAGTCATACCTTCCGAACATTCGGAAGCGATCGCACGACCTGATGC
AGCCCAAGGGAATTTAGCCACTTCGTAGTTTAAGCCTTCTTGCTTACACTCTTTCTCCGTTTTACCTACC
CAAGCAACTTCCGGCTCTGTATAAGCGATTGAAGGAATCACTTTAGGATCGAAGTAGTGTTTTTGACCGG
CAATCACTTCTGCCGCTACATGACCTTCGTGAACACCTTTGTGTGCTAACATCGGCTGACCTACGATATC
ACCGATAGCGAAGATATGCGGTACGTTGGTACGCATTTGTTTATCCACTGCGATGAAACCGCGATCATCA
ACATTCACGCCCGCTTTACCCGCATCGATTAATTTACCGTTCGGTACACGACCGATAGCGACTAATACCG
CATCGTAACGTTTAGTATCGTTACATGCTTTACCTTCCATTGAAACATAGATACCGTCATCTTTCGCTTC
AACCGCAGTTACTTTAGTTTCAAGCATTAACTTGAATTTTTTCTCGATTTGTTTGGTGTAGATAGCTACA
ACATCTTTATCTGCTGCAGGAATCACTTGGTCAAACATCTCAACCACTTCAACTTCCGAACCTAAAGCGT
TATACACGGTACCCATTTCTAAACCGATGATACCACCGCCCATAATGAGTAATTTTTTCGGTACTTCTTT
TAATTTAAGTGCATCCGTAGAATCCCACACACGCGGATCTTCGTGTGGAATGAACGGAAGCTGAATCGGA
CGAGAACCGGCTGCAATAATTGCATTATCAAATTTAATCGTTGTCGGATTACCGTCACGGTCACGAGCTA
CTAAAGTATTCGGATCGGTAAACGTCGCTAAACCTTCCACTACTGTTACTTTACGTGCTTTAGCCATACC
CGCTAAACCGCCGGTTAATTTAGAAACAACCGCTTCTTTACCCGCACGCACTTTATCTAAATCAATGTTG
GGCTCACCGAAAGTAATACCGTTTTTCTCTGCGTGTTTTGCTTCTTCGATAACTTTTGCAACGTGTAATA
ATGCTTTAGACGGAATACAACCTACGTTTAAGCATACACCGCCCAAAGTTGAATAACGTTCGACAATTAC
TGTTTCTAAGCCTAAGTCGGCACAACGGAATGCCGCTGAATAACCGGCAGGACCCGCACCAAGTACCACG
ACTTGCGTTTTGATTTCTTTGCTCA
Protein Sequence 
>gi|165976188|ref|YP_001651781.1| dihydrolipoamide dehydrogenase [Actinobacillus pleuropneumoniae serovar 3 str. JL03] MSKEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYSTLGGVCLNVGCIPSKALLHVAKVIEEAKHAEKNGITFGEPNIDLDKVRAGKEAVVSKLTGGLAGMAKARKVTVVEGLATFTDPNTLVARDRDGNPTTIKFDNAIIAAGSRPIQLPFIPHEDPRVWDSTDALKLKEVPKKLLIMGGGIIGLEMGTVYNALGSEVEVVEMFDQVIPAADKDVVAIYTKQIEKKFKLMLETKVTAVEAKDDGIYVSMEGKACNDTKRYDAVLVAIGRVPNGKLIDAGKAGVNVDDRGFIAVDKQMRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEVIAGQKHYFDPKVIPSIAYTEPEVAWVGKTEKECKQEGLNYEVAKFPWAASGRAIASECSEGMTKLIFDKDTHRLLGGAIVGSNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHESVGLAAEVFEGSITDLPNAKAKKR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lpdA mutant is attenuated in porcine model of infection (Fuller et al., 2000).
COG COG1249C, under C: Energy production and conversion
References
Fuller et al., 2000: Fuller TE, Martin S, Teel JF, Alaniz GR, Kennedy MJ, Lowery DE. Identification of Actinobacillus pleuropneumoniae virulence genes using signature-tagged mutagenesis in a swine infection model. Microbial pathogenesis. 2000; 29(1); 39-51. [PubMed: 10873489].