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dnaK from Actinobacillus pleuropneumoniae L20

Victor ID 4034
Gene Name dnaK from Actinobacillus pleuropneumoniae L20
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae L20
NCBI Gene ID 4848587
NCBI Protein GI 126209366
Locus Tag APL_1906
Protein Accession YP_001054591.1
Other Database IDs UniProtKB-ID: DNAK_ACTP2
UniRef100: UniRef100_A3N3K0
UniRef90: UniRef90_Q4QJW4
UniRef50: UniRef50_P38646
UniParc: UPI0000397C7E
EMBL: CP000569
EMBL-CDS: ABN74986.1
RefSeq_NT: NC_009053.1
GenomeReviews: CP000569_GR
KEGG: apl:APL_1906
eggNOG: COG0443
HOGENOM: HBG334976
OMA: KANNGDA
ProtClustDB: PRK00290
BioCyc: APLE416269:APL_1906-MONOMER
Taxonomy ID 416269
Gene Starting Position 2136556
Gene Ending Position 2138454
Gene Strand (Orientation) -
Protein Name molecular chaperone DnaK
DNA Sequence 
>gi|126207488:2136556-2138454 Actinobacillus pleuropneumoniae L20, complete genome
ATTATTTATTATCTTTCACTTCTTCAAACTCAGCATCCACTACGCCGTCATCTTTTGCAGATTGTTGCGG
TTGTTCACCTGCTTGCGCTTTAGCTTGAGCCGCTTGCATTAAAGGTTCGGACGCTTTGATTAACGCTTCA
GTTTTCGCATCGATTTCTGCTTTATCATCGCCTTTAGCCGCTTTTTCTAAGTCAGCGATAGCTGCTTCGA
TTTTCGCTTTATCATCTGCATTTAACGCATCACCAGCTTCTTCGATTTGTTTACGAGTTGCATGCGCGAT
ACCGTCCGCTTGGTTACGTGCTTGAACTAACTCTTCGAATTTTTTATCCGCTTCTGCGTTAGCTTCCGCA
TCACGAACCATTTGTTCGATTTCTTCGTCAGATAAACCTGAAGACGCTTGGATACGGATTTGTTGCTCTT
TACCTGTATTTTTATCTTTCGCAGATACGTTGATTACACCGTTCGCATCGATATCGAAAGTTACTTCGAT
TTGCGGCATACCACGTGGTGCTGGGTTAATACCTTCAAGGTTGAATTGACCTAAAGATTTGTTCGCAGAC
GCTTGTTTACGCTCACCTTGTAATACGTGGATCGTTACCGCTGATTGATTGTCTTCCGCGGTTGAGAACA
CTTGTGATTTCTTCGTTGGAATCGTAGTGTTTTTCTCAATTAACACGGTCATCACGCCGCCCATAGTTTC
GATACCTAAAGATAATGGTGTAACGTCTAATAAAAGAACGTCTTTTACATCACCTTTTAATACACCGCCT
TGAACTGCAGCACCGATTGCTACCGCTTCATCCGGATTCACGTCTTTACGAGCTTCTTTACCGAAGAATT
CAGCCACTTTTTGTTGTACTAACGGCATACGTGTTTGACCACCAACGAGGATAATGTCGTTGATTTCATT
CACTGATTTACCTGCGTCTTTTAATACGGTTTTAAGTGACTCGATTGAGCTTGCAACTAAATCTTCTACT
AATGCTTCTAATTTCGCACGGGTTACGTTGATCGCTAAGTGTTTAGGACCTGTCGCATCCGCTGTGATAT
ACGGAAGATTTACTTCGGTAGATTGTGCTGAAGAAAGTTCGATTTTCGCTTTTTCCGCCGCTTCTTTAAC
ACGTTGTAATGCCATTGGGTCGTTGCGTAAATCCACGCCTTGTTCTTTTTTGAACTCGTCAATAATGTAG
TCGATTACACGGTTATCGAAGTCCTCACCACCTAAGTGAGTGTTACCGCCGGTTGCTAATACTTCGAATG
TTTGTTCGCCGTCGAAGTTATCGATTTCGATGATTGAGATATCGAATGTACCACCACCTAAGTCGTAAAC
TGCGATCACTTGGTTTTCTTTAGTTGAACCTAAACCGAACGCTAACGCTGCTGCTGTCGGTTCGTTGATG
ATACGTTTAACATCTAAACCTGCGATACGACCTGCATCGATTGTCGCTTGACGTTGCGCATCGTTAAAGT
ATGCCGGCACAGTGATAACCGCTTCAGTTACCGCTTCACCAAGGAAATCTTCCGCTGTTTTTTTCATTTT
TTTCAACACTTCTGCTGAAATTTGCGGTGGTGCTAACTTATCGCCTTTTACGTTTACCCATGCATCGCCG
TTGTCAGCACGTGTGATTTCGAAAGGCATAATTTTAATATCGCGTTGTACTTCTTCACTTTCAAAACGAC
GACCGATTAAACGTTTGATTGCAAATAATGTATTTTTCGGGTTTGTAATCGCCTGACGTTTTGCCGGTTG
ACCAACTAACGTTTCGTTATCCGTATAAGCAATGATTGACGGAGTTGTACGTGCACCTTCCGCATTCTCG
ATTACACGTGCTTTGTCACCGTCCATTACCGCTACACAAGAGTTTGTTGTACCTAAGTCAATACCAATGA
TTTTACCCA
Protein Sequence 
>gi|126209366|ref|YP_001054591.1| molecular chaperone DnaK [Actinobacillus pleuropneumoniae serovar 5b str. L20] MGKIIGIDLGTTNSCVAVMDGDKARVIENAEGARTTPSIIAYTDNETLVGQPAKRQAITNPKNTLFAIKRLIGRRFESEEVQRDIKIMPFEITRADNGDAWVNVKGDKLAPPQISAEVLKKMKKTAEDFLGEAVTEAVITVPAYFNDAQRQATIDAGRIAGLDVKRIINEPTAAALAFGLGSTKENQVIAVYDLGGGTFDISIIEIDNFDGEQTFEVLATGGNTHLGGEDFDNRVIDYIIDEFKKEQGVDLRNDPMALQRVKEAAEKAKIELSSAQSTEVNLPYITADATGPKHLAINVTRAKLEALVEDLVASSIESLKTVLKDAGKSVNEINDIILVGGQTRMPLVQQKVAEFFGKEARKDVNPDEAVAIGAAVQGGVLKGDVKDVLLLDVTPLSLGIETMGGVMTVLIEKNTTIPTKKSQVFSTAEDNQSAVTIHVLQGERKQASANKSLGQFNLEGINPAPRGMPQIEVTFDIDANGVINVSAKDKNTGKEQQIRIQASSGLSDEEIEQMVRDAEANAEADKKFEELVQARNQADGIAHATRKQIEEAGDALNADDKAKIEAAIADLEKAAKGDDKAEIDAKTEALIKASEPLMQAAQAKAQAGEQPQQSAKDDGVVDAEFEEVKDNK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dnaK mutant is attenuated in porcine model of infection (Fuller et al., 2000).
COG COG0443O, under O: Posttranslational modification, protein turnover, chaperones
References
Fuller et al., 2000: Fuller TE, Martin S, Teel JF, Alaniz GR, Kennedy MJ, Lowery DE. Identification of Actinobacillus pleuropneumoniae virulence genes using signature-tagged mutagenesis in a swine infection model. Microbial pathogenesis. 2000; 29(1); 39-51. [PubMed: 10873489].