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apxIIID

Victor ID 4942
Gene Name apxIIID
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae serovar 2
NCBI Nucleotide GI 470687
Protein Accession AAA21926.1
Other Database IDs CDD:130902
Taxonomy ID 34063
Gene Strand (Orientation) ?
Protein Name RTX toxin
Protein Note type I secretion membrane fusion protein, HlyD family; TIGR01843
DNA Sequence
Protein Sequence 
>gi|470687|gb|AAA21926.1| RTX toxin [Actinobacillus pleuropneumoniae serovar 2]
MKLWILGLGEFFQRYRNIWREIWKIRKQLDTPARQKDENEFLPRHLELIETPISKKPRLIAYLIMLFLFL
AIVISIISKVEIVASATGKLVFSGHSKEIKPIENALVKDIFVKDGQFVEKGQLLLNLTALGCDADKQKTK
VSLGLERLDGYRYKSLLYSIEHNRLPLLDFNQADFDSVQEEDKTGARHLITEQFETWQKQKYQKELAYQR
KQAEKQTVLANIRKYESASRIEKEKLSDLKKLYDVKSISKHELLAQENRYVEASNELSVYQSHLKEVESD
LLKAQEDLKLVTQLFKSDILEKLQQNIQREKQLTLELEKNEQRQLASIIRAPVSGTVQQLKTHTKGGVVT
TAETLMVIAPEDDVLEVSALIQNKDVGFVEIGQEAVIKVETFPYTRYGYLYGKVKTITLDAIEHPQLGLV
FNSIIEINKKTLTDGDKEIQLGSGMSVIAEIKTGERSVISFLLSPLEESITESLRER
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: An apxIIIB mutant, in combination with an apxIIID mutation, is highly attenuated in pigs (Park et al., 2009).
References
Park et al., 2009: Park C, Ha Y, Kim S, Chae C, Ryu DY. Construction and characterization of an Actinobacillus pleuropneumoniae serotype 2 mutant lacking the Apx toxin secretion protein genes apxIIIB and apxIIID. The Journal of veterinary medical science / the Japanese Society of Veterinary Science. 2009; 71(10); 1317-1323. [PubMed: 19887737].